Search Results - "Christensen, Robbin"
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Phase I Pharmacokinetic and Pharmacodynamic Study of the Multikinase Inhibitor Sorafenib in Combination With Clofarabine and Cytarabine in Pediatric Relapsed/Refractory Leukemia
Published in Journal of clinical oncology (20-08-2011)“…To assess the toxicity, pharmacokinetics, and pharmacodynamics of multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in children…”
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Long-Term Efficacy of Methylphenidate in Enhancing Attention Regulation, Social Skills, and Academic Abilities of Childhood Cancer Survivors
Published in Journal of clinical oncology (10-10-2010)“…Methylphenidate (MPH) ameliorates attention problems experienced by some cancer survivors in the short term, but its long-term efficacy is unproven. This study…”
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Octreotide Therapy of Pediatric Hypothalamic Obesity: A Double-Blind, Placebo-Controlled Trial
Published in The journal of clinical endocrinology and metabolism (01-06-2003)“…Hypothalamic obesity is a devastating complication in children surviving brain tumors and/or cranial irradiation. These subjects are thought to exhibit…”
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Short-Term Efficacy of Methylphenidate: A Randomized, Double-Blind, Placebo-Controlled Trial Among Survivors of Childhood Cancer
Published in Journal of clinical oncology (01-12-2004)“…Children surviving acute lymphoblastic leukemia (ALL) and malignant brain tumors (BTs) have a higher incidence of attention and learning problems in school…”
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Alternative formulations of sorafenib for use in children
Published in Pediatric blood & cancer (01-10-2013)“…Background Sorafenib is an oral multikinase inhibitor with antiangiogenic and antitumor activity. In most cases, the commercially available 200 mg tablet is…”
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Immediate Neurocognitive Effects of Methylphenidate on Learning-Impaired Survivors of Childhood Cancer
Published in Journal of clinical oncology (15-03-2001)“…To test if methylphenidate (MPH) has an objective beneficial effect on immediate performance on tests of neurocognitive functions among learning-impaired…”
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Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial
Published in The Lancet infectious diseases (01-08-2020)“…(+)-SJ000557733 (SJ733) is a novel, orally bioavailable inhibitor of Plasmodium falciparum ATP4. In this first-in-human and induced blood-stage malaria phase…”
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A randomized double‐blind placebo‐controlled trial of the effectiveness of melatonin on neurocognition and sleep in survivors of childhood cancer
Published in Pediatric blood & cancer (01-01-2022)“…Background Adult survivors of childhood cancer are at risk of developing sleep and neurocognitive problems, yet few efficacious interventions exist targeting…”
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Efficacy of Glucarpidase (Carboxypeptidase G2) in Patients with Acute Kidney Injury After High-Dose Methotrexate Therapy
Published in Pharmacotherapy (01-05-2014)“…Study Objective Because the incidence rate of renal impairment is 2–10% for patients treated with high‐dose methotrexate and renal impairment develops in…”
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Smaller white‐matter volumes are associated with larger deficits in attention and learning among long‐term survivors of acute lymphoblastic leukemia
Published in Cancer (15-02-2006)“…BACKGROUND The primary objective of this study was to test the hypothesis that survivors of childhood acute lymphoblastic leukemia (ALL) have deficits in…”
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Acute Neurocognitive Response to Methylphenidate Among Survivors of Childhood Cancer: A Randomized, Double-Blind, Cross-Over Trial
Published in Journal of pediatric psychology (01-10-2007)“…Objective To investigate the acute efficacy and adverse side effects of methylphenidate (MPH) among survivors of childhood cancer [acute lymphoblastic leukemia…”
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Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study
Published in Clinical trials (London, England) (01-08-2016)“…Background/aims: Neuropathic pain is a known component of vaso-occlusive pain in sickle cell disease; however, drugs targeting neuropathic pain have not been…”
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Stability of Cyclophosphamide in Extemporaneous Oral Suspensions
Published in The Annals of pharmacotherapy (01-02-2010)“…Background: Cyclophosphamide, an alkylating agent, is widely used for the treatment of many adult and pediatric malignancies. The stability of cyclophosphamide…”
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Stability of Sunitinib in Oral Suspension
Published in The Annals of pharmacotherapy (01-07-2008)“…Background: Sunitinib Is a novel, oral, multitargeted tyrosine kinase Inhibitor with antiangiogenic and antitumor activity. No liquid formulation of sunitinib…”
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