Search Results - "Christensen, Niels J"

Stability mechanisms of a thermophilic laccase probed by molecular dynamics by Christensen, Niels J, Kepp, Kasper P

“…Laccases are highly stable, industrially important enzymes capable of oxidizing a large range of substrates. Causes for their stability are, as for other…”
Get full text

Cutaneous noradrenaline measured by microdialysis in complex regional pain syndrome during whole-body cooling and heating by Terkelsen, Astrid J., Gierthmühlen, Janne, Petersen, Lars J., Knudsen, Lone, Christensen, Niels J., Kehr, Jan, Yoshitake, Takashi, Madsen, Caspar S., Wasner, Gunnar, Baron, Ralf, Jensen, Troels S.

“…Complex regional pain syndrome (CRPS) is characterised by autonomic, sensory, and motor disturbances. The underlying mechanisms of the autonomic changes in…”
Get full text

Accurate Stabilities of Laccase Mutants Predicted with a Modified FoldX Protocol by Christensen, Niels J, Kepp, Kasper P

“…Fungal laccases are multicopper enzymes of industrial importance due to their high stability, multifunctionality, and oxidizing power. This paper reports…”
Get full text

Stability Mechanisms of Laccase Isoforms using a Modified FoldX Protocol Applicable to Widely Different Proteins by Christensen, Niels J, Kepp, Kasper P

“…A recent computational protocol that accurately predicts and rationalizes protein multisite mutant stabilities has been extended to handle widely different…”
Get full text

The human spleen as an erythrocyte reservoir in diving-related interventions by Espersen, Kurt, Frandsen, Hans, Lorentzen, Torben, Kanstrup, Inge-Lis, Christensen, Niels J

“…Departments of 1  Clinical Physiology and Nuclear Medicine and 2  Ultrasound and 3  Division of Endocrinology, Herlev Hospital, University of Copenhagen,…”
Get full text

Setting the stage for electron transfer: Molecular basis of ABTS-binding to four laccases from Trametes versicolor at variable pH and protein oxidation state by Christensen, Niels J., Kepp, Kasper P.

“…•The molecular basis of Km variation across laccases was explored.•Clustering analysis revealed distinct classes of Trametes laccases.•Our results partially…”
Get full text

Methyl Effect in Azumamides Provides Insight Into Histone Deacetylase Inhibition by Macrocycles by Maolanon, Alex R, Villadsen, Jesper S, Christensen, Niels J, Hoeck, Casper, Friis, Tina, Harris, Pernille, Gotfredsen, Charlotte H, Fristrup, Peter, Olsen, Christian A

“…Natural, nonribosomal cyclotetrapeptides have traditionally been a rich source of inspiration for design of potent histone deacetylase (HDAC) inhibitors. We…”
Get full text

Circulatory responses to lower body negative pressure in young Afghans and Danes: implications for understanding ethnic effects on blood pressure regulation by Asmar, Ali, Bülow, Jens, Simonsen, Lene, Rasmussen, Jonas G., Christensen, Niels J., Frandsen, Erik, Norsk, Peter

“…Purpose We have previously shown that Afghans residing in Denmark for at least 12 years exhibit a lower 24-h ambulatory blood pressure compared to Danes. The…”
Get full text

Metal Ion Controlled Self-Assembly of a Chemically Reengineered Protein Drug Studied by Small-Angle X‑ray Scattering by Nygaard, Jesper, Munch, Henrik K, Thulstrup, Peter W, Christensen, Niels J, Hoeg-Jensen, Thomas, Jensen, Knud J, Arleth, Lise

“…Precise control of the oligomeric state of proteins is of central importance for biological function and for the properties of biopharmaceutical drugs. Here,…”
Get full text

Blood pressure in Afghan male immigrants to Denmark by Asmar, Ali, Bülow, Jens, Simonsen, Lene, Christensen, Niels J., Frandsen, Erik, Norsk, Peter

“…Summary Purpose Immigration from a Third‐World society to a Western society can be associated with higher blood pressure and salt sensitivity. We therefore…”
Get full text

Glycemic control in diabetes in three Danish counties by Jørgensen, Lone G M, Petersen, Per Hyltoft, Heickendorff, Lene, Møller, Holger Jon, Hendel, Jørn, Christensen, Cramer, Schmitz, Anita, Reinholdt, Birgitte, Lund, Erik D, Christensen, Niels J, Hansen, Erik Kjaersgaard, Hastrup, Jens, Skjødt, Hanne, Eriksen, Ebbe Wendel, Brandslund, Ivan

“…Hemoglobin A1c (HbA1c) is a proxy measure for glycemic control in diabetes. We investigated the trend for glycemic control in patients from three Danish…”
Get more information

Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation by Malik, Leila, Nygaard, Jesper, Christensen, Niels J., Streicher, Werner W., Thulstrup, Peter W., Arleth, Lise, Jensen, Knud J.

“…α‐Helical coiled coil structures, which are noncovalently associated heptad repeat peptide sequences, are ubiquitous in nature. Similar amphipathic repeat…”
Get full text

Molecular Interactions between Barley and Oat β-Glucans and Phenolic Derivatives by Simonsen, Henrik Toft, Nielsen, Mette S, Christensen, Niels J, Christensen, Ulla, La Cour, Thomas V, Motawia, Mohammed Saddik, Jespersen, Birthe P. M, Engelsen, Søren B, Møller, Birger Lindberg

“…Equilibrium dialysis, molecular modeling, and multivariate data analysis were used to investigate the nature of the molecular interactions between 21…”
Get full text

Sympathetic nervous activity decreases during head-down bed rest but not during microgravity by Christensen, Niels J, Heer, Martina, Ivanova, Krassimira, Norsk, Peter

“…1 Department of Endocrinology, Herlev University Hospital, University of Copenhagen, Denmark; 2 Deutsche Forschungsanstalt für Luft und Raumfahrt-Institute of…”
Get full text

The cAMP response to isoprenaline in mononuclear cells is markedly increased in the presence of platelets by Christensen, Niels J., Bratholm, Palle

“…We have previously shown that the addition of platelets to mononuclear cells (MNC) increases cAMP in MNC. This response may be of interest because the physical…”
Get full text

Resistant starch: the effect on postprandial glycemia, hormonal response, and satiety by Raben, A, Tagliabue, A, Christensen, NJ, Madsen, J, Holst, JJ, Astrup, A

“…The effect of resistant starch (RS) on postprandial plasma concentrations of glucose, lipids, and hormones, and on subjective satiety and palatability ratings…”
Get full text

NO modulates norepinephrine release in human skeletal muscle: implications for neural preconditioning by Costa, F, Christensen, N J, Farley, G, Biaggioni, I

“…The purpose of this study was to estimate muscle interstitial norepinephrine (NE) levels during exercise and to determine whether nitric oxide (NO) modulates…”
Get more information

Renal and sympathoadrenal responses in space by Christensen, Niels J., Drummer, Christian, Norsk, Peter

“…According to a classic hypothesis, weightlessness should promote the renal excretion rate of sodium and water and lead to a fluid- and electrolyte-depleted…”
Get full text

Sympathetic nervous activity decreases during head down bed rest but not during microgravity by Christensen, Niels J, Heer, Martina, Ivanova, Krassimira, Norsk, Peter

“…Platelet norepinephrine (NE) and epinephrine (E) were measured as indices of long-term changes in sympathoadrenal activity. Ten normal healthy subjects were…”
Get full text

Fluid balance and kidney function in space by De Santo, Natale G., Christensen, Niels J., Drummer, Christian, Kramer, Herbert J., Regnard, Jacques, Heer, Martina, Cirillo, Massimo, Norsk, Peter

Get full text