Search Results - "Christensen, Lanette M"

Nuclear Coregulatory Complexes in Tregs as Targets to Promote Anticancer Immune Responses by Christensen, Lanette M., Hancock, Wayne W.

“…T-regulatory (Treg) cells display considerable heterogeneity in their responses to various cancers. The functional differences among this cell type are heavily…”
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T-regulatory cells require Sin3a for stable expression of Foxp3 by Christensen, Lanette M, Akimova, Tatiana, Wang, Liqing, Han, Rongxiang, Samanta, Arabinda, Di Giorgio, Eros, Hancock, Wayne W

“…Histone deacetylases 1 and 2 play a major role in the transcriptional regulation of T-regulatory (Treg) cells via interactions with a myriad of coregulatory…”
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MEF2D sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity by Di Giorgio, Eros, Wang, Liqing, Xiong, Yan, Akimova, Tatiana, Christensen, Lanette M, Han, Rongxiang, Samanta, Arabinda, Trevisanut, Matteo, Bhatti, Tricia R, Beier, Ulf H, Hancock, Wayne W

“…The transcription factor MEF2D is important in the regulation of differentiation and adaptive responses in many cell types. We found that among T cells, MEF2D…”
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Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity by Akimova, Tatiana, Wang, Liqing, Bartosh, Zhanna, Christensen, Lanette M, Eruslanov, Evgeniy, Singhal, Sunil, Aishwarya, Veenu, Hancock, Wayne W

“…Our goal is to improve the outcomes of cancer immunotherapy by targeting FOXP3+ T-regulatory (Treg) cells with a next generation of antisense oligonucleotides…”
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Legionella pneumophila p45 element influences host cell entry and sensitivity to sodium by Christensen, Lanette M, Sule, Preeti, Strain, Madison, Cirillo, Jeffrey D

“…Legionella pneumophila are environmental bacteria found ubiquitously in both natural and man-made water reservoirs, sometimes as constituents of biofilm…”
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A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells by Di Giorgio, Eros, Wang, Liqing, Xiong, Yan, Christensen, Lanette M, Akimova, Tatiana, Han, Rongxiang, Samanta, Arabinda, Trevisanut, Matteo, Brancolini, Claudio, Beier, Ulf H, Hancock, Wayne W

“…The Mads/Mef2 (Mef2a/b/c/d) family of transcription factors (TFs) regulates differentiation of muscle cells, neurons and hematopoietic cells. By functioning in…”
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Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo by Siska, Peter J., Jiao, Jing, Matos, Carina, Singer, Katrin, Berger, Raffaela S., Dettmer, Katja, Oefner, Peter J., Cully, Michelle D., Wang, Zhonglin, QuinnIII, William J., Oliff, Kristen N., Wilkins, Benjamin J., Christensen, Lanette M., Wang, Liqing, Hancock, Wayne W., Baur, Joseph A., Levine, Matthew H., Ugele, Ines, Mayr, Roman, Renner, Kathrin, Zhou, Liang, Kreutz, Marina, Beier, Ulf H.

“…L-kynurenine is a tryptophan-derived immunosuppressive metabolite and precursor to neurotoxic anthranilate and quinolinate. We evaluated the stereoisomer…”
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Control of Foxp3+ Treg Production, Stability and Function by the Nuclear Co‐regulator, Sin3A by Christensen, Lanette M., Akimova, Tatiana, Han, Rongxiang, Wang, Liqing, Samanta, Arabinda, Hancock, Wayne W.

“…Purpose Foxp3+ T‐regulatory (Treg) cells are well established as a crucial component of immune homeostasis and self‐tolerance. Histone/protein deacetylase…”
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Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia-Reperfusion Injury by Akimova, Tatiana, Zhang, Tianyi, Christensen, Lanette M, Wang, Zhonglin, Han, Rongxiang, Negorev, Dmitry, Samanta, Arabinda, Sasson, Isaac E, Gaddapara, Trivikram, Jiao, Jing, Wang, Liqing, Bhatti, Tricia R, Levine, Matthew H, Diamond, Joshua M, Beier, Ulf H, Simmons, Rebecca A, Cantu, Edward, Wilkes, David S, Lederer, David J, Anderson, Michaela, Christie, Jason D, Hancock, Wayne W

“…Primary graft dysfunction (PGD) is a severe form of acute lung injury, leading to increased early morbidity and mortality after lung transplant. Obesity is a…”
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Legionnaires’ Disease Mortality in Guinea Pigs Involves the p45 Mobile Genomic Element by Christensen, Lanette M, Sule, Preeti, Cirillo, Suat L G, Strain, Madison, Plumlee, Quinci, Adams, L Garry, Cirillo, Jeffrey D

“…Abstract Background Legionella can cause Legionnaires’ disease, a potentially fatal form of pneumonia that occurs as sporadic epidemics. Not all strains…”
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Sin3A Controls FoxP3+ Treg Production, Stability and Function by Christensen, Lanette M, Akimova, Tatiana, Han, Rongxaing, Wang, Liqing, Samanta, Arabinda, Hancock, Wayne W

“…Abstract Purpose: Foxp3 T-regulatory (Treg) cells are key to immune homeostasis but the function of paired amphipathic helix protein, Sin3a, is unknown…”
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MEF2D sustains activation of effector [Foxp3.sup.+] Tregs during transplant survival and anticancer immunity by Giorgio, Eros Di, Wang, Liqing, Xiong, Yan, Akimova, Tatiana, Christensen, Lanette M, Han, Rongxiang, Samanta, Arabinda, Trevisanut, Matteo, Bhatti, Tricia R, Beier, Ulf H, Hancock, Wayne W

“…The transcription factor MEF2D is important in the regulation of differentiation and adaptive responses in many cell types. We found that among T cells, MEF2D…”
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Evaluation of the P45 Mobile Integrative Element and Its Role in Legionella pneumophila Virulence by Christensen, Lanette M

“…Legionella pneumophila are aqueous environmental bacilli that live within protozoal species and cause a potentially fatal form of pneumonia called…”
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