Search Results - "Christen, Deborah"
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Immunoglobulins to mitigate paraneoplastic Lambert Eaton Myasthenic Syndrome under checkpoint inhibition in Merkel cell carcinoma
Published in Neurological research and practice (09-12-2020)“…Lambert-Eaton myasthenic syndrome (LEMS) is a rare, autoimmune or paraneoplastic condition characterized by muscle weakness and fatigability. In cancer…”
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Quality of Life Analysis in Patients with AA Using the QLQ-AA/PNH-54 at Initial Diagnosis of AA - a Registry Based Analysis
Published in Blood (02-11-2023)“…Objectives: Aplastic anemia (AA) and paroxysmal nocturnal hemoglobinuria (PNH) are ultra-rare, acquired bone marrow failure syndromes (BMFS) with need for…”
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Allogeneic Hematopoietic Stem Cell Transplantation in Advanced Systemic Mastocytosis
Published in Blood (02-11-2023)“…Purpose Advanced systemic mastocytosis (AdvSM) is driven by the KIT D816V mutation in >90% of patients (pts.). Depending on subtype, median survival is between…”
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Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis: A retrospective analysis of the DRST and GREM registries
Published in Leukemia (01-04-2024)“…We identified 71 patients with AdvSM (aggressive SM [ASM], SM with an associated hematologic neoplasm [SM-AHN, e.g., acute myeloid leukemia, SM-AML], mast cell…”
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Prevalence of hypersensitivity reactions in various forms of mastocytosis: A pilot study of 2485 adult patients with mastocytosis collected in the ECNM registry
Published in Allergy (Copenhagen) (01-09-2024)“…Background Hypersensitivity reactions (HR) are common in mastocytosis. However, little is known about triggers and risk factors. The registry of the European…”
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Poor Applicability of Currently Available Prognostic Scoring Systems for Prediction of Outcome in IKIT/I D816V-Negative Advanced Systemic Mastocytosis
Published in Cancers (01-01-2024)“…Most patients (>95%) with systemic mastocytosis (SM) carry a mutation in the KIT gene (KIT D816V). Especially aggressive forms of SM are associated with…”
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Towards personalized medicine with iPS cell technology: a case report of advanced systemic mastocytosis with associated eosinophilia
Published in Annals of hematology (01-11-2022)Get full text
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Poor Applicability of Currently Available Prognostic Scoring Systems for Prediction of Outcome in KIT D816V-Negative Advanced Systemic Mastocytosis
Published in Cancers (30-01-2024)“…Within our nationwide registry, we identified a D816V mutation ( D816V in 280/299 (94%) patients with advanced systemic mastocytosis (AdvSM). Age, cytopenias…”
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Capitalizing on paradoxical activation of the mitogen‐activated protein kinase pathway for treatment of Imatinib‐resistant mast cell leukemia
Published in Hematological oncology (01-08-2023)“…Prevention of fatal side effects during cancer therapy of cancer patients with high‐dosed pharmacological inhibitors is to date a major challenge. Moreover,…”
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Outcome of non-mold effective anti-fungal prophylaxis in patients at high-risk for invasive fungal infections after allogenic stem cell transplantation
Published in Leukemia & lymphoma (03-07-2019)“…Patients who develop severe graft-versus-host disease (GvHD) after allogeneic stem cell transplantation (alloSCT) have a higher risk for invasive fungal…”
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Serum chemistry profiling and prognostication in systemic mastocytosis: a registry-based study of the ECNM and GREM
Published in Blood advances (11-06-2024)“…•Serum chemistry profiling is of diagnostic and prognostic relevance based on easily accessible parameters.•Serum chemistry markers help to assess and quantify…”
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Leukopenia - A Diagnostic Guideline for the Clinical Routine
Published in Deutsche medizinische Wochenschrift (1946) (01-11-2017)“…Reasons for leukopenia can be numerous. To get close to the diagnosis it's always useful to check previous blood counts of the patient to get a feeling for the…”
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