Search Results - "Chrisler, William B."

Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC‐MS by Zhu, Ying, Clair, Geremy, Chrisler, William B., Shen, Yufeng, Zhao, Rui, Shukla, Anil K., Moore, Ronald J., Misra, Ravi S., Pryhuber, Gloria S., Smith, Richard D., Ansong, Charles, Kelly, Ryan T.

“…We report on the quantitative proteomic analysis of single mammalian cells. Fluorescence‐activated cell sorting was employed to deposit cells into a newly…”
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Groundwater–surface water mixing shifts ecological assembly processes and stimulates organic carbon turnover by Stegen, James C., Fredrickson, James K., Wilkins, Michael J., Konopka, Allan E., Nelson, William C., Arntzen, Evan V., Chrisler, William B., Chu, Rosalie K., Danczak, Robert E., Fansler, Sarah J., Kennedy, David W., Resch, Charles T., Tfaily, Malak

“…Environmental transitions often result in resource mixtures that overcome limitations to microbial metabolism, resulting in biogeochemical hotspots and…”
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High-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform by Dou, Maowei, Clair, Geremy, Tsai, Chia-Feng, Xu, Kerui, Chrisler, William B, Sontag, Ryan L, Zhao, Rui, Moore, Ronald J, Liu, Tao, Pasa-Tolic, Ljiljana, Smith, Richard D, Shi, Tujin, Adkins, Joshua N, Qian, Wei-Jun, Kelly, Ryan T, Ansong, Charles, Zhu, Ying

“…Effective extension of mass spectrometry-based proteomics to single cells remains challenging. Herein we combined microfluidic nanodroplet technology with…”
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ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies by Hinderliter, Paul M, Minard, Kevin R, Orr, Galya, Chrisler, William B, Thrall, Brian D, Pounds, Joel G, Teeguarden, Justin G

“…The difficulty of directly measuring cellular dose is a significant obstacle to application of target tissue dosimetry for nanoparticle and microparticle…”
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Influences of organic carbon speciation on hyporheic corridor biogeochemistry and microbial ecology by Stegen, James C., Johnson, Tim, Fredrickson, James K., Wilkins, Michael J., Konopka, Allan E., Nelson, William C., Arntzen, Evan V., Chrisler, William B., Chu, Rosalie K., Fansler, Sarah J., Graham, Emily B., Kennedy, David W., Resch, Charles T., Tfaily, Malak, Zachara, John

“…The hyporheic corridor (HC) encompasses the river–groundwater continuum, where the mixing of groundwater (GW) with river water (RW) in the HC can stimulate…”
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Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor by Wiley, H Steven, Shankaran, Harish, Ippolito, Danielle L, Chrisler, William B, Resat, Haluk, Bollinger, Nikki, Opresko, Lee K

“…Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To…”
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Phototrophic biofilm assembly in microbial-mat-derived unicyanobacterial consortia: model systems for the study of autotroph-heterotroph interactions by Cole, Jessica K, Hutchison, Janine R, Renslow, Ryan S, Kim, Young-Mo, Chrisler, William B, Engelmann, Heather E, Dohnalkova, Alice C, Hu, Dehong, Metz, Thomas O, Fredrickson, Jim K, Lindemann, Stephen R

“…Microbial autotroph-heterotroph interactions influence biogeochemical cycles on a global scale, but the diversity and complexity of natural systems and their…”
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Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics by Tsai, Chia-Feng, Zhang, Pengfei, Scholten, David, Martin, Kendall, Wang, Yi-Ting, Zhao, Rui, Chrisler, William B., Patel, Dhwani B., Dou, Maowei, Jia, Yuzhi, Reduzzi, Carolina, Liu, Xia, Moore, Ronald J., Burnum-Johnson, Kristin E., Lin, Miao-Hsia, Hsu, Chuan-Chih, Jacobs, Jon M., Kagan, Jacob, Srivastava, Sudhir, Rodland, Karin D., Steven Wiley, H., Qian, Wei-Jun, Smith, Richard D., Zhu, Ying, Cristofanilli, Massimo, Liu, Tao, Liu, Huiping, Shi, Tujin

“…Large numbers of cells are generally required for quantitative global proteome profiling due to surface adsorption losses associated with sample processing…”
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Organelle-Specific Activity-Based Protein Profiling in Living Cells by Wiedner, Susan D., Anderson, Lindsey N., Sadler, Natalie C., Chrisler, William B., Kodali, Vamsi K., Smith, Richard D., Wright, Aaron T.

“…A multimodal activity‐based probe for targeting acidic organelles was developed to measure subcellular native enzymatic activity in cells by fluorescence…”
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Phycobilisome truncation causes widespread proteome changes in Synechocystis sp. PCC 6803 by Liberton, Michelle, Chrisler, William B, Nicora, Carrie D, Moore, Ronald J, Smith, Richard D, Koppenaal, David W, Pakrasi, Himadri B, Jacobs, Jon M

“…In cyanobacteria such as Synechocystis sp. PCC 6803, large antenna complexes called phycobilisomes (PBS) harvest light and transfer the energy to the…”
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Phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture by Khan, Nymul, Maezato, Yukari, McClure, Ryan S., Brislawn, Colin J., Mobberley, Jennifer M., Isern, Nancy, Chrisler, William B., Markillie, Lye Meng, Barney, Brett M., Song, Hyun-Seob, Nelson, William C., Bernstein, Hans C.

“…The fundamental question of whether different microbial species will co-exist or compete in a given environment depends on context, composition and…”
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Unlocking the Constraints of Cyanobacterial Productivity: Acclimations Enabling Ultrafast Growth by Bernstein, Hans C, McClure, Ryan S, Hill, Eric A, Markillie, Lye Meng, Chrisler, William B, Romine, Margie F, McDermott, Jason E, Posewitz, Matthew C, Bryant, Donald A, Konopka, Allan E, Fredrickson, James K, Beliaev, Alexander S

“…Harnessing the metabolic potential of photosynthetic microbes for next-generation biotechnology objectives requires detailed scientific understanding of the…”
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Aerosolized ZnO Nanoparticles Induce Toxicity in Alveolar Type II Epithelial Cells at the Air-Liquid Interface by Xie, Yumei, Williams, Nolann G., Tolic, Ana, Chrisler, William B., Teeguarden, Justin G., Maddux, Bettye L.S., Pounds, Joel G., Laskin, Alexander, Orr, Galya

“…The majority of in vitro studies characterizing the impact of engineered nanoparticles (NPs) on cells that line the respiratory tract were conducted in cells…”
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A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics by Tsai, Chia-Feng, Wang, Yi-Ting, Hsu, Chuan-Chih, Kitata, Reta Birhanu, Chu, Rosalie K., Velickovic, Marija, Zhao, Rui, Williams, Sarah M., Chrisler, William B., Jorgensen, Marda L., Moore, Ronald J., Zhu, Ying, Rodland, Karin D., Smith, Richard D., Wasserfall, Clive H., Shi, Tujin, Liu, Tao

“…Effective phosphoproteome of nanoscale sample analysis remains a daunting task, primarily due to significant sample loss associated with non-specific surface…”
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Spatial Proteomics toward Subcellular Resolution by Coupling Deep Ultraviolet Laser Ablation with Nanodroplet Sample Preparation by Xiang, Piliang, Liyu, Andrey, Kwon, Yumi, Hu, Dehong, Williams, Sarah M., Veličković, Dušan, Markillie, Lye Meng, Chrisler, William B., Paša-Tolić, Ljiljana, Zhu, Ying

“…Multiplexed molecular profiling of tissue microenvironments, or spatial omics, can provide critical insights into cellular functions and disease pathology. The…”
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Extensive cellular multi-tasking within Bacillus subtilis biofilms by Yannarell, Sarah M, Beaudoin, Eric S, Talley, Hunter S, Schoenborn, Alexi A, Orr, Galya, Anderton, Christopher R, Chrisler, William B, Shank, Elizabeth A

“…is a soil-dwelling bacterium that can form biofilms, or communities of cells surrounded by a self-produced extracellular matrix. In biofilms, genetically…”
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Sensitive Targeted Quantification of ERK Phosphorylation Dynamics and Stoichiometry in Human Cells without Affinity Enrichment by Shi, Tujin, Gao, Yuqian, Gaffrey, Matthew J, Nicora, Carrie D, Fillmore, Thomas L, Chrisler, William B, Gritsenko, Marina A, Wu, Chaochao, He, Jintang, Bloodsworth, Kent J, Zhao, Rui, Camp, David G, Liu, Tao, Rodland, Karin D, Smith, Richard D, Wiley, H. Steven, Qian, Wei-Jun

“…Targeted mass spectrometry is a promising technology for site-specific quantification of posttranslational modifications. However, a major constraint is the…”
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Analysis of carbohydrate storage granules in the diazotrophic cyanobacterium Cyanothece sp. PCC 7822 by Welkie, David G, Sherman, Debra M, Chrisler, William B, Orr, Galya, Sherman, Louis A

“…The unicellular diazotrophic cyanobacteria of the genus Cyanothece demonstrate oscillations in nitrogenase activity and H₂ production when grown under 12 h…”
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Publisher Correction: Influences of organic carbon speciation on hyporheic corridor biogeochemistry and microbial ecology by Stegen, James C., Johnson, Tim, Fredrickson, James K., Wilkins, Michael J., Konopka, Allan E., Nelson, William C., Arntzen, Evan V., Chrisler, William B., Chu, Rosalie K., Fansler, Sarah J., Graham, Emily B., Kennedy, David W., Resch, Charles T., Tfaily, Malak, Zachara, John

“…The original version of this Article contained an error in Fig. 6e, in which the text in the legend was omitted. This has been corrected in both the PDF and…”
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Predicting Species-Resolved Macronutrient Acquisition during Succession in a Model Phototrophic Biofilm Using an Integrated 'Omics Approach by Lindemann, Stephen R, Mobberley, Jennifer M, Cole, Jessica K, Markillie, L M, Taylor, Ronald C, Huang, Eric, Chrisler, William B, Wiley, H S, Lipton, Mary S, Nelson, William C, Fredrickson, James K, Romine, Margaret F

“…The principles governing acquisition and interspecies exchange of nutrients in microbial communities and how those exchanges impact community productivity are…”
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