Search Results - "Chretien, Marie‐Lorraine"
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Adherence to immunomodulatory drugs in patients with multiple myeloma
Published in PloS one (27-03-2019)“…Immunomodulatory drugs (thalidomide, lenalidomide and pomalidomide; IMID) are widely used in the treatment of multiple myeloma patients. To date, few data are…”
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Efficacy, safety, and cost of pomalidomide in relapsed and refractory multiple myeloma
Published in European journal of haematology (01-05-2018)“…Objectives To investigate the efficacy, safety, and cost of a pomalidomide‐dexamethasone regimen in patients with relapsed and refractory multiple myeloma…”
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Self‐management of immunomodulatory drug treatment in multiple myeloma patients
Published in European journal of cancer care (01-01-2021)“…Objective Immunomodulatory drugs (IMIDs: thalidomide, lenalidomide and pomalidomide) are widely used in patients with multiple myeloma (MM). The aim of our…”
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Factors influencing access to specialised haematology units during acute myeloblastic leukaemia patient care: A population‐based study in France
Published in Cancer medicine (Malden, MA) (01-04-2023)“…Background The excess mortality observed in Acute Myeloblastic Leukaemia (AML) patients, partly attributed to unequal access to curative treatments, could be…”
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Front-line transplantation program with lenalidomide, bortezomib, and dexamethasone combination as induction and consolidation followed by lenalidomide maintenance in patients with multiple myeloma: a phase II study by the Intergroupe Francophone du Myélome
Published in Journal of clinical oncology (01-09-2014)“…The three-drug combination of lenalidomide, bortezomib, and dexamethasone (RVD) has shown significant efficacy in multiple myeloma (MM). The Intergroupe…”
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A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial
Published in Leukemia (01-01-2020)“…Patients with multiple myeloma are generally older and vary in fitness levels, which may influence the clinical benefit of treatment. Patients from the large,…”
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Daratumumab, carfilzomib, lenalidomide, and dexamethasone with tandem transplant for high-risk newly diagnosed myeloma
Published in Blood (16-05-2024)“…•D-KRd induction and consolidation with double transplant is feasible in HR TE-NDMM.•D-KRd with double transplant result in high rates of MRD negativity, PFS,…”
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Development and Validation of a Cytogenetic Prognostic Index Predicting Survival in Multiple Myeloma
Published in Journal of clinical oncology (01-07-2019)“…The wide heterogeneity in multiple myeloma (MM) outcome is driven mainly by cytogenetic abnormalities. The current definition of high-risk profile is…”
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In Multiple Myeloma, High-Risk Secondary Genetic Events Observed at Relapse Are Present From Diagnosis in Tiny, Undetectable Subclonal Populations
Published in Journal of clinical oncology (20-03-2023)“…Multiple myeloma (MM) is characterized by copy number abnormalities (CNAs), some of which influence patient outcomes and are sometimes observed only at…”
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Early achievement of measurable residual disease negativity in the treatment of multiple myeloma as predictor of outcome
Published in British journal of haematology (01-06-2022)Get full text
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Biallelic deletion of 1p32 defines ultra-high-risk myeloma, but monoallelic del(1p32) remains a strong prognostic factor
Published in Blood (16-03-2023)“…•Del(1p32) is an independent and important adverse prognostic factor in myeloma.•Biallelic deletion of 1p32 dramatically worsens the prognosis compared with a…”
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Primary plasma cell leukemias displaying t(11;14) have specific genomic, transcriptional, and clinical features
Published in Blood (28-04-2022)“…Primary plasma cell leukemia (pPCL) is an aggressive form of multiple myeloma (MM) that has not benefited from recent therapeutic advances in the field…”
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Gilteritinib activity in refractory or relapsed FLT3-mutated acute myeloid leukemia patients previously treated by intensive chemotherapy and midostaurin: a study from the French AML Intergroup ALFA/FILO
Published in Leukemia (01-01-2023)“…The real-world efficacy and safety of gilteritinib was assessed in an ambispective study that included 167 R/R FLT3 -mutated AML patients. Among them, 140…”
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IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association
Published in Oncotarget (08-12-2015)“…Acute myeloid leukemia (AML) is a heterogeneous disease. Even within the same NPM1-mutated genetic subgroup, some patients harbor additional mutations in FLT3,…”
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Role of additional chromosomal changes in the prognostic value of t(4;14) and del(17p) in multiple myeloma: the IFM experience
Published in Blood (26-03-2015)“…In multiple myeloma, cytogenetic changes are important predictors of patient outcome. In this setting, the most important changes are deletion 17p, del(17p),…”
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Upfront autologous stem cell transplantation for newly diagnosed elderly multiple myeloma patients: a prospective multicenter study
Published in Haematologica (Roma) (01-11-2016)“…The feasibility and efficacy of high-dose melphalan followed by autologous hematopoietic stem cell transplantation in newly diagnosed elderly patients with…”
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Ponatinib evaluation and safety in real-life chronic myelogenous leukemia patients failing more than two tyrosine kinase inhibitors: the PEARL observational study
Published in Experimental hematology (01-11-2018)“…•We report the use of ponatinib in chronic myelogenous leukemia (CML) patients who failed at least two lines of tyrosine kinase inhibitors (TKI) in a real-life…”
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Daratumumab and dexamethasone is safe and effective for triple refractory myeloma patients: final results of the IFM 2014‐04 (Etoile du Nord) trial
Published in British journal of haematology (01-11-2019)“…Summary Single agent daratumumab has shown clinical activity in relapsed, refractory multiple myeloma (RRMM). The Intergroupe Francophone du Myélome 2014‐04…”
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Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma
Published in Blood (22-12-2016)“…Guidelines for monitoring multiple myeloma (MM) patients expressing light chains only (light-chain MM [LCMM]) rely on measurements of monoclonal protein in…”
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