Search Results - "Chrétien, Marie‐Lorraine"
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1
Early achievement of measurable residual disease negativity in the treatment of multiple myeloma as predictor of outcome
Published in British journal of haematology (01-06-2022)Get full text
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2
Ponatinib evaluation and safety in real-life chronic myelogenous leukemia patients failing more than two tyrosine kinase inhibitors: the PEARL observational study
Published in Experimental hematology (01-11-2018)“…•We report the use of ponatinib in chronic myelogenous leukemia (CML) patients who failed at least two lines of tyrosine kinase inhibitors (TKI) in a real-life…”
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3
Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma
Published in Blood (22-12-2016)“…Guidelines for monitoring multiple myeloma (MM) patients expressing light chains only (light-chain MM [LCMM]) rely on measurements of monoclonal protein in…”
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4
Cost and efficacy of peripheral stem cell mobilization strategies in multiple myeloma
Published in Bone marrow transplantation (Basingstoke) (01-12-2020)“…Mobilization of peripheral blood stem cells (PBSC) can be performed using plerixafor, which is expensive, or high-dose cyclophosphamide (HDCy). We hypothesized…”
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Nosocomial Infections with IMP-19-Producing Pseudomonas aeruginosa Linked to Contaminated Sinks, France
Published in Emerging infectious diseases (01-02-2017)“…We isolated IMP-19-producing Pseudomonas aeruginosa from 7 patients with nosocomial infections linked to contaminated sinks in France. We showed that bla was…”
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Extending autologous transplantation as first line therapy in multiple myeloma patients with severe renal impairment: a retrospective study by the SFGM-TC
Published in Bone marrow transplantation (Basingstoke) (01-06-2018)“…Renal impairment is a common complication of multiple myeloma (MM), accounting for 20–30% of MM patients at diagnosis and 40–50% of patients during the course…”
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HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis
Published in Nature communications (12-04-2018)“…Heat shock protein 27 (HSP27/HSPB1) is a stress-inducible chaperone that facilitates cancer development by its proliferative and anti-apoptotic functions. The…”
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Antibody–Drug Conjugates for the Treatment of Hematological Malignancies: A Comprehensive Review
Published in Targeted oncology (01-06-2018)“…Antibody–drug conjugates (ADCs) are an emerging class of therapeutic agents that bring new opportunities for the treatment of hematological malignancies by…”
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Myeloma MRD by deep sequencing from circulating tumor DNA does not correlate with results obtained in the bone marrow
Published in Blood advances (13-11-2018)“…•There is no correlation between ctDNA and bone marrow for MRD by NGS using only immunoglobulin gene rearrangements in myeloma patients…”
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Outbreak of Extended-Spectrum Beta-Lactamase Producing Enterobacter cloacae with High MICs of Quaternary Ammonium Compounds in a Hematology Ward Associated with Contaminated Sinks
Published in Frontiers in microbiology (12-07-2016)“…To investigate an outbreak of extended-spectrum beta-lactamase (ESBL) producing Enterobacter cloacae that occurred in the Hematology ward (24-bed unit) of the…”
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Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment
Published in Cancer cell (09-04-2018)“…Tumor-promoting inflammation and avoiding immune destruction are hallmarks of cancer. Here, we demonstrate that the pro-inflammatory cytokine interleukin…”
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12
Carfilzomib Weekly plus Melphalan and Prednisone in Newly Diagnosed Transplant-Ineligible Multiple Myeloma (IFM 2012-03): A Phase I Trial
Published in Clinical cancer research (15-07-2019)“…Carfilzomib is a novel generation proteasome inhibitor. The Carmysap trial demonstrated that twice-weekly KMP (carfilzomib, melphalan, prednisone) might…”
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13
BAM conditioning before autologous transplantation for lymphoma: a study on behalf of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
Published in Annals of hematology (01-08-2019)“…High-dose chemotherapy before autologous transplantation is a therapeutic option as consolidation in primary or relapsed lymphoma. Even if BEAM conditioning is…”
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14
CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts
Published in Oncotarget (04-10-2016)“…CD45 is a pan-leukocyte protein with tyrosine phosphatase activity involved in the regulation of signal transduction in hematopoiesis. Exploiting CD45 KO mice…”
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Trim33/Tif1γ is involved in late stages of granulomonopoiesis in mice
Published in Experimental hematology (01-08-2016)“…Trim33/Tif1γ (Trim33) is a member of the tripartite motif family. Using a conditional hematopoietic-specific Trim33 knock-out (Trim33Δ/Δ ) mouse, we showed…”
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Identification of novel, clonally stable, somatic mutations targeting transcription factors PAX5 and NKX2-3, the epigenetic regulator LRIF1, and BRAF in a case of atypical B-cell chronic lymphocytic leukemia harboring a t(14;18)(q32;q21)
Published in Cold Spring Harbor molecular case studies (01-02-2021)“…Diagnosis of B-cell chronic lymphocytic leukemia (B-CLL) is usually straightforward, involving clinical, immunophenotypic (Matutes score), and (immuno)genetic…”
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17
Nosocomial Infections with IMP-19−Producing Pseudomonas aeruginosa Linked to Contaminated Sinks, France
Published in Emerging infectious diseases (01-02-2017)Get full text
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18
Adherence to immunomodulatory drugs in patients with multiple myeloma
Published in PloS one (27-03-2019)“…Immunomodulatory drugs (thalidomide, lenalidomide and pomalidomide; IMID) are widely used in the treatment of multiple myeloma patients. To date, few data are…”
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Real-world study of the efficacy and safety of belantamab mafodotin (GSK2857916) in relapsed or refractory multiple myeloma based on data from the nominative ATU in France: IFM 2020-04 study
Published in Haematologica (Roma) (01-10-2023)“…Belantamab mafodotin (BM) is an anti-BCMA antibody-drug conjugate (GSK2857916) that represents an alternative option in multiple myeloma. We sought to assess…”
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Efficacy, safety, and cost of pomalidomide in relapsed and refractory multiple myeloma
Published in European journal of haematology (01-05-2018)“…Objectives To investigate the efficacy, safety, and cost of a pomalidomide‐dexamethasone regimen in patients with relapsed and refractory multiple myeloma…”
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