Search Results - "Choy, Young Bin"

The Rule of Five for Non-Oral Routes of Drug Delivery: Ophthalmic, Inhalation and Transdermal by Choy, Young Bin, Prausnitz, Mark R.

“…ABSTRACT The Rule of Five predicts suitability of drug candidates, but was developed primarily using orally administered drugs. Here, we test whether the Rule…”
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Thermosensitive hexanoyl glycol chitosan-based ocular delivery system for glaucoma therapy by Cho, Ik Sung, Park, Chun Gwon, Huh, Beom Kang, Cho, Myeong Ok, Khatun, Zehedina, Li, Zhengzheng, Kang, Sun-Woong, Choy, Young Bin, Huh, Kang Moo

“…[Display omitted] Conventional eye drops quickly move away from the surface of the eye; as a result, ocular bioavailability is very limited. To overcome this…”
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Review of clay-drug hybrid materials for biomedical applications; administration routes by Kim, Myung Hun, Choi, Goeun, Elzatahry, Ahmed, Vinu, Ajayan, Choy, Young Bin, Choy, Jin-Ho

“…Focus here is placed on the pharmaceutical and biomedical applications of novel clay-drug hybrid materials categorized by methods of administration. Clay…”
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Controlled release of donepezil intercalated in smectite clays by Park, Jin Kuen, Choy, Young Bin, Oh, Jae-Min, Kim, Ju Young, Hwang, Seong-Ju, Choy, Jin-Ho

“…The inorganic–organic hybrid for a drug delivery system was successfully realized by intercalating donepezil molecules into smectite clays (laponite XLG,…”
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A microneedle roller for transdermal drug delivery by Park, Jung-Hwan, Choi, Seong-O, Seo, Soonmin, Choy, Young Bin, Prausnitz, Mark R.

“…Polymer microneedle rollers, prepared from replicated polymer films, offer a simple way to increase skin permeability for drug delivery. The diagram shows the…”
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Dry Tablet Formulation of PLGA Nanoparticles with a Preocular Applicator for Topical Drug Delivery to the Eye by Ryu, Woo Mi, Kim, Se-Na, Min, Chang Hee, Choy, Young Bin

“…To enhance ocular drug bioavailability, a rapidly dissolving dry tablet containing alginate and drug-loaded poly(lactic- -glycolic acid) (PLGA) nanoparticles…”
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Mucoadhesive microparticles with a nanostructured surface for enhanced bioavailability of glaucoma drug by Park, Chun Gwon, Kim, Young Kook, Kim, Mi Jeung, Park, Min, Kim, Myung Hun, Lee, Seung Ho, Choi, Sung Yoon, Lee, Won Seok, Chung, You Jung, Jung, Young Eun, Park, Ki Ho, Choy, Young Bin

“…Topical drug administration to the eye is limited by low drug bioavailability due to its rapid clearance from the preocular surface. Thus, multiple daily…”
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Silicone breast implant modification review: overcoming capsular contracture by Shin, Byung Ho, Kim, Byung Hwi, Kim, Sujin, Lee, Kangwon, Choy, Young Bin, Heo, Chan Yeong

“…Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular…”
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Modulation of Foreign Body Reaction against PDMS Implant by Grafting Topographically Different Poly(acrylic acid) Micropatterns by Lee, Jae Sang, Shin, Byung Ho, Yoo, Byoung Yong, Nam, Sun‐Young, Lee, Miji, Choi, Juhwan, Park, Hansoo, Choy, Young Bin, Heo, Chan Yeong, Koh, Won‐Gun

“…The surface of poly(dimethylsiloxane) (PDMS) is grafted with poly(acrylic acid) (PAA) layers via surface‐initiated photopolymerization to suppress the capsular…”
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Wirelessly Controlled Implantable System for On-demand and Pulsatile Insulin Administration by Lee, Seung Ho, Ahn, Joong Woo, Cho, Yong Chan, Kim, Se-Na, Lee, Cheol, Ku, Gi Won, Bin Choy, Young, Kim, Hee Chan

“…We propose a wirelessly controlled implantable system for on-demand and pulsatile insulin delivery with a more convenient and safer strategy than currently…”
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Synergistic Effect of Whitlockite Scaffolds Combined with Alendronate to Promote Bone Regeneration by Jeong, Jiwoon, Shim, Jung Hee, Koo, Bum Mo, Choy, Young Bin, Heo, Chan Yeong

“…Due to the increasing aging of society, the number of patients suffering from senile diseases is increasing. Patients suffering from osteoporosis, which is a…”
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Laponite-based nanohybrid for enhanced solubility and controlled release of itraconazole by Jung, Hyun, Kim, Hyun-Mi, Choy, Young Bin, Hwang, Seong-Ju, Choy, Jin-Ho

“…Laponite, a form of layered aluminosilicates, and itraconazole, a water insoluble drug, were hybridized through an interfacial reaction at the boundary between…”
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Mucoadhesive microparticles engineered for ophthalmic drug delivery by Choy, Young Bin, Park, Jung-Hwan, Prausnitz, Mark R.

“…Although topical drug delivery is a convenient route of administration to treat various eye diseases, it has serious limitations due to rapid clearance of the…”
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Inorganic-polymer nanohybrid carrier for delivery of a poorly-soluble drug, ursodeoxycholic acid by Choi, Goeun, Lee, Ji-Hee, Oh, Yeon-Ji, Choy, Young Bin, Park, Myung Chul, Chang, Hee Chul, Choy, Jin-Ho

“…Delivery of poorly soluble drugs has been problematic due to its low absorption profile and bioavailability. In this work, ursodeoxycholic acid (UDCA), a…”
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Uniform ethyl cellulose microspheres of controlled sizes and polymer viscosities and their drug-release profiles by Choy, Young Bin, Choi, Hyungsoo, Kim, Kyekyoon

“…Monodisperse ethyl cellulose (EC) microspheres (MSs) of three size groups (20-35, 55-60, and 80-105 μm in diameter) were fabricated to study the effect of the…”
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Mucoadhesive Microdiscs Engineered for Ophthalmic Drug Delivery: Effect of Particle Geometry and Formulation on Preocular Residence Time by Choy, Young Bin, Park, Jung-Hwan, McCarey, Bernard E, Edelhauser, Henry F, Prausnitz, Mark R

“…To test the hypothesis that mucoadhesive microdiscs formulated in a rapidly dissolving tablet can increase preocular residence time. Microparticles smaller…”
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Monodisperse Gelatin Microspheres as a Drug Delivery Vehicle: Release Profile and Effect of Crosslinking Density by Choy, Young Bin, Cheng, Felice, Choi, Hyungsoo, Kim, Kyekyoon (Kevin)

“…Uniform gelatin microspheres (GMS) of a wet size of 100 µm in diameter were fabricated by the electric field assisted precision particle fabrication (E‐PPF)…”
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A nanohybrid system for taste masking of sildenafil by Lee, Ji-Hee, Choi, Goeun, Oh, Yeon-Ji, Park, Je Won, Choy, Young Bin, Park, Mung Chul, Yoon, Yeo Joon, Lee, Hwa Jeong, Chang, Hee Chul, Choy, Jin-Ho

“…A nanohybrid was prepared with an inorganic clay material, montmorillonite (MMT), for taste masking of sildenafil (SDN). To further improve the taste-masking…”
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Noninvasive Self-diagnostic Device for Tear Collection and Glucose Measurement by Lee, Seung Ho, Cho, Yong Chan, Bin Choy, Young

“…We propose a noninvasive, self-diagnostic device that enables safe tear collection and glucose measurement. The device described herein was manufactured by…”
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Application of Materials as Medical Devices with Localized Drug Delivery Capabilities for Enhanced Wound Repair by Lee, Esther J, Huh, Beom Kang, Kim, Se Na, Lee, Jae Yeon, Park, Chun Gwon, Mikos, Antonios G, Choy, Young Bin

“…The plentiful assortment of natural and synthetic materials can be leveraged to accommodate diverse wound types, as well as different stages of the healing…”
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