Search Results - "Choy, Mankin"

Frequency-selective control of cortical and subcortical networks by central thalamus by Liu, Jia, Lee, Hyun Joo, Weitz, Andrew J, Fang, Zhongnan, Lin, Peter, Choy, ManKin, Fisher, Robert, Pinskiy, Vadim, Tolpygo, Alexander, Mitra, Partha, Schiff, Nicholas, Lee, Jin Hyung

“…Central thalamus plays a critical role in forebrain arousal and organized behavior. However, network-level mechanisms that link its activity to brain state…”
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Activation of Direct and Indirect Pathway Medium Spiny Neurons Drives Distinct Brain-wide Responses by Lee, Hyun Joo, Weitz, Andrew J., Bernal-Casas, David, Duffy, Ben A., Choy, ManKin, Kravitz, Alexxai V., Kreitzer, Anatol C., Lee, Jin Hyung

“…A central theory of basal ganglia function is that striatal neurons expressing the D1 and D2 dopamine receptors exert opposing brain-wide influences. However,…”
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High-sensitivity detection of optogenetically-induced neural activity with functional ultrasound imaging by Edelman, Bradley Jay, Ielacqua, Giovanna D., Chan, Russell W., Asaad, Mazen, Choy, Mankin, Lee, Jin Hyung

“…Whole-brain imaging approaches and optogenetic manipulations are powerful tools to map brain-wide neural circuits in vivo. To date, functional magnetic…”
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Predicting Successful Generation and Inhibition of Seizure-like Afterdischarges and Mapping Their Seizure Networks Using fMRI by Duffy, Ben A., Choy, ManKin, Lee, Jin Hyung

“…To understand the conditions necessary to initiate and terminate seizures, we investigate optogenetically induced hippocampal seizures with LFP, fMRI, and…”
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The chronic vascular and haemodynamic response after permanent bilateral common carotid occlusion in newborn and adult rats by Choy, ManKin, Ganesan, Vijeya, Thomas, David L, Thornton, John S, Proctor, Edward, King, Martin D, van der Weerd, Louise, Gadian, David G, Lythgoe, Mark F

“…Vascular growth and redistribution of flow can compensate for arterial occlusion and possibly reduce the effects of hypoperfusion. As yet there is limited…”
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Inflammatory Processes, Febrile Seizures, and Subsequent Epileptogenesis: Inflammatory Processes, Febrile Seizures, and Subsequent Epileptogenesis by Choy, ManKin, Dubé, Céline M., Ehrengruber, Markus, Baram, Tallie Z.

“…Febrile seizures (FS) are the most common type of seizures in infants and preschool children. Inflammatory mediators, which are known triggers of fever, have…”
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Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain by Cleary, Jon O., Wiseman, Frances K., Norris, Francesca C., Price, Anthony N., Choy, ManKin, Tybulewicz, Victor L.J., Ordidge, Roger J., Brandner, Sebastian, Fisher, Elizabeth M.C., Lythgoe, Mark F.

“…Extensive worldwide efforts are underway to produce knockout mice for each of the ~25,000 mouse genes, which may give new insights into the underlying…”
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Optogenetic fMRI reveals distinct, frequency-dependent networks recruited by dorsal and intermediate hippocampus stimulations by Weitz, Andrew J., Fang, Zhongnan, Lee, Hyun Joo, Fisher, Robert S., Smith, Wesley C., Choy, ManKin, Liu, Jia, Lin, Peter, Rosenberg, Matthew, Lee, Jin Hyung

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Thalamic Input to Orbitofrontal Cortex Drives Brain-wide, Frequency-Dependent Inhibition Mediated by GABA and Zona Incerta by Weitz, Andrew J., Lee, Hyun Joo, Choy, ManKin, Lee, Jin Hyung

“…Anatomical and behavioral data suggest that the ventrolateral orbitofrontal cortex (VLO), which exhibits extensive connectivity and supports diverse sensory…”
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A comparative study of the ability of calcitonin gene‐related peptide and adrenomedullin13–52 to modulate microvascular but not thermal hyperalgesia responses by Chu, Duc Quyen, Choy, ManKin, Foster, Paul, Cao, Thong, Brain, Susan D

“…Calcitonin gene‐related peptide (CGRP), a neuropeptide, is a potent vasodilator. Adrenomedullin (ADM) is suggested to be produced by vascular cells in inflamed…”
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High spatial resolution compressed sensing (HSPARSE) functional MRI by Fang, Zhongnan, Van Le, Nguyen, Choy, ManKin, Lee, Jin Hyung

“…Purpose To propose a novel compressed sensing (CS) high spatial resolution functional MRI (fMRI) method and demonstrate the advantages and limitations of using…”
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Optogenetic study of networks in epilepsy by Choy, ManKin, Duffy, Ben A., Lee, Jin Hyung

“…Currently, approximately 30% of patients with epilepsy do not have adequate seizure control. A greater understanding of the underlying mechanisms by which…”
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Optogenetic fMRI reveals distinct, frequency-dependent networks recruited by dorsal and intermediate hippocampus stimulations by Weitz, Andrew J, Fang, Zhongnan, Lee, Hyun Joo, Fisher, Robert S, Smith, Wesley C, Choy, ManKin, Liu, Jia, Lin, Peter, Rosenberg, Matthew, Lee, Jin Hyung

“…Although the connectivity of hippocampal circuits has been extensively studied, the way in which these connections give rise to large-scale dynamic network…”
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Repeated hippocampal seizures lead to brain-wide reorganization of circuits and seizure propagation pathways by Choy, ManKin, Dadgar-Kiani, Ehsan, Cron, Greg O., Duffy, Ben A., Schmid, Florian, Edelman, Bradley J., Asaad, Mazen, Chan, Russell W., Vahdat, Shahabeddin, Lee, Jin Hyung

“…Repeated seizure activity can lead to long-term changes in seizure dynamics and behavior. However, resulting changes in brain-wide dynamics remain poorly…”
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MRI compatible optrodes for simultaneous LFP and optogenetic fMRI investigation of seizure-like afterdischarges by Duffy, Ben A., Choy, ManKin, Chuapoco, Miguel R., Madsen, Michael, Lee, Jin Hyung

“…In preclinical studies, implanted electrodes can cause severe degradation of MRI images and hence are seldom used for chronic studies employing functional…”
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Carbon monofilament electrodes for unit recording and functional MRI in same subjects by Chuapoco, Miguel R., Choy, Mankin, Schmid, Florian, Duffy, Ben A., Lee, Hyun Joo, Lee, Jin Hyung

“…Extracellular electrophysiology and functional MRI are complementary techniques that provide information about cellular and network-level neural activity,…”
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Abstract TMP117: Optogenetic Stimulation Effects On Cortico-thalamic Circuit Plasticity After Stroke by Chiang, Terrance, Vahdat, Shahabeddin, Pendharkar, Arjun, Harvey, Sean, Uchino, Haruto, Cao, Zhijuan, Kim, Anika, Choy, Mankin, Chen, Hansen, Lee, Hyun Joo, Cheng, Michelle Y, LEE, JIN HYUNG, Steinberg, Gary

“…IntroductionPost-stroke optogenetic stimulation in the ipsilesional primary motor cortex (iM1) can promote functional recovery. Recent brain imaging data…”
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High Spatial Resolution Compressed Sensing (HSPARSE) Functional Magnetic Resonance Imaging by Fang, Zhongnan, Van Le, Nguyen, Choy, ManKin, Lee, Jin Hyung

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A novel, noninvasive, predictive epilepsy biomarker with clinical potential by Choy, ManKin, Dubé, Celine M, Patterson, Katelin, Barnes, Samuel R, Maras, Pamela, Blood, Arlin B, Hasso, Anton N, Obenaus, Andre, Baram, Tallie Z

“…A significant proportion of temporal lobe epilepsy (TLE), a common, intractable brain disorder, arises in children with febrile status epilepticus (FSE)…”
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Epilepsy‐predictive magnetic resonance imaging changes following experimental febrile status epilepticus: Are they translatable to the clinic? by Curran, Megan M., Haddad, Elizabeth, Patterson, Katelin P., Choy, Mankin, Dubé, Celine M., Baram, Tallie Z., Obenaus, Andre

“…Summary Objective A subset of children with febrile status epilepticus (FSE) are at risk for development of temporal lobe epilepsy later in life. We sought a…”
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