Search Results - "Choy, KW"

MicroRNA from a 12-h versus 20-h acetylcysteine infusion for paracetamol overdose by Wong, A, Nejad, C, Gantier, M, Choy, K W, Doery, James, Graudins, A

“…Paracetamol overdose is common and microRNA (miR)-122 expression is increased with liver injury. We aimed to measure miR-122 in the setting of an abbreviated…”
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The impact of human copy number variation on a new era of genetic testing by Choy, KW, Setlur, SR, Lee, C, Lau, TK

“…Please cite this paper as: Choy K, Setlur S, Lee C, Lau T. The impact of human copy number variation on a new era of genetic testing. BJOG 2010;117:391–397…”
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Debates on fetal fraction measurement and DNA‐based noninvasive prenatal screening: time for standardisation? by Wataganara, T, Bui, T‐H, Choy, KW, Leung, TY

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Aqueous Humor Levels of Vascular Endothelial Growth Factor and Pigment Epithelium–Derived Factor in Polypoidal Choroidal Vasculopathy and Choroidal Neovascularization by Tong, Jian-Ping, Chan, Wai-Man, Liu, David T.L., Lai, Timothy Y.Y., Choy, Kwong-Wai, Pang, Chi-Pui, Lam, Dennis S.C.

“…To determine the aqueous levels of vascular endothelial growth factor (VEGF) and pigment epithelium–derived factor (PEDF) in patients with active polypoidal…”
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Women's preference for non‐invasive prenatal DNA testing versus chromosomal microarray after screening for Down syndrome: a prospective study by Cheng, YKY, Leung, WC, Leung, TY, Choy, KW, Chiu, RWK, Lo, T‐K, Kwok, KY, Sahota, DS

“…Objective To examine preferences for follow‐up testing in women screened with high or intermediate risk for Down syndrome in the first or second trimester…”
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Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain by Liu, Xiaodong, Tian, Yuanyuan, Meng, Zhaoyu, Chen, Yan, Ho, Idy H. T., Choy, Kwong Wai, Lichtner, Peter, Wong, Sunny H., Yu, Jun, Gin, Tony, Wu, William K. K., Cheng, Christopher H. K., Chan, Matthew T. V.

“…Abstract Background: Proteases have been shown to modulate pain signaling in the spinal cord and may contribute to the development of chronic postsurgical…”
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Chromosomal abnormalities and neurological outcomes in fetal cerebral ventriculomegaly: a retrospective cohort analysis by Lok, W Y, Kong, C W, Hui, S Y A, Shi, M M, Choy, K W, To, W K, Leung, T Y

“…This study investigated the incidences of chromosomal abnormalities and the neurological outcomes according to the degree of fetal cerebral ventriculomegaly…”
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Intermediate- to long-term outcomes of transvaginal mesh for treatment of Asian women with pelvic organ prolapse by Chan, S S C, Wan, O Y K, Choy, K W, Cheung, R Y K

“…Short-term follow-up analyses suggest that transvaginal mesh has limited application for pelvic organ prolapse (POP) treatment. This study evaluated the…”
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Expanded carrier screening using next-generation sequencing of 123 Hong Kong Chinese families: a pilot study by Chan, O Y M, Leung, T Y, Cao, Y, Shi, M M, Kwan, A H W, Chung, J P W, Choy, K W, Chong, S C

“…To determine the carrier frequency and common mutations of Mendelian variants in Chinese couples using next-generation sequencing (NGS). Preconception expanded…”
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Amniotic fluid gamma-glutamyl transferase for prediction of biliary atresia in cases of non-visualisation of the fetal gallbladder: a retrospective study using a validated analytical platform and local reference range by Cheung, T Y T, Wong, N K L, Sahota, D S, Subramaniam, S R, Lau, S L, Zhu, X, Lui, W T, Chan, E K W, Kwok, Y K Y, Choy, K W, Leung, T Y, Chan, M H M, Wong, F C K, Ting, Y H

“…The level of amniotic fluid gamma-glutamyl transferase (AFGGT) may help identify biliary atresia (BA) in cases of non-visualisation of the fetal gallbladder…”
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Diagnostic accuracy of the BACs‐on‐Beads™ assay versus karyotyping for prenatal detection of chromosomal abnormalities: a retrospective consecutive case series by Choy, KW, Kwok, YK, Cheng, YKY, Wong, KM, Wong, HK, Leung, KO, Suen, KW, Adler, K, Wang, CC, Lau, TK, Schermer, MJ, Lao, TT, Leung, TY

“…Objective To evaluate the diagnostic performance of the BACs‐on‐Beads™ (BoBs™) assay for prenatal detection of chromosomal abnormalities. Design Retrospective…”
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Identification of fragile X pre-mutation carriers in the Chinese obstetric population using a robust FMR1 polymerase chain reaction assay: implications for screening and prenatal diagnosis by Cheng, Y Ky, Lin, C Sw, Kwok, Y Ky, Chan, Y M, Lau, T K, Leung, T Y, Choy, K W

“…There is significant morbidity associated with fragile X syndrome. Unfortunately, most maternal carriers are clinically silent during their reproductive years…”
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SNaPshot reveals high mutation and carrier frequencies of 15 common hearing loss mutants in a Chinese newborn cohort by Chen, Y., Cao, Y., Li, H.-B., Mao, J., Liu, M.-J., Liu, Y.-H., Wang, B.-J., Jiang, D., Zhu, Q., Ding, Y., Wang, W., Li, H., Choy, K.W.

“…Genetic causes account for more than half of congenital hearing loss cases. The most frequent mutations found in non‐syndromic hearing loss patients occur in…”
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Diagnostic accuracy of the BAC s‐on‐Beads ™ assay versus karyotyping for prenatal detection of chromosomal abnormalities: a retrospective consecutive case series by Choy, KW, Kwok, YK, Cheng, YKY, Wong, KM, Wong, HK, Leung, KO, Suen, KW, Adler, K, Wang, CC, Lau, TK, Schermer, MJ, Lao, TT, Leung, TY

“…Objective To evaluate the diagnostic performance of the BAC s‐on‐Beads ™ (BoBs ™ ) assay for prenatal detection of chromosomal abnormalities. Design…”
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The short Synacthen test and laboratory assay inter-ference by Kw, Choy, Kh, Choy

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Detection of cryptic pathogenic copy number variations and constitutional loss of heterozygosity using high resolution SNP microarray analysis in 117 patients referred for cytogenetic analysis and impact on clinical practice by Bruno, D L, Ganesamoorthy, D, Schoumans, J, Bankier, A, Coman, D, Delatycki, M, Gardner, R J M, Hunter, M, James, P A, Kannu, P, McGillivray, G, Pachter, N, Peters, H, Rieubland, C, Savarirayan, R, Scheffer, I E, Sheffield, L, Tan, T, White, S M, Yeung, A, Bowman, Z, Ngo, C, Choy, K W, Cacheux, V, Wong, L, Amor, D J, Slater, H R

“…Microarray genome analysis is realising its promise for improving detection of genetic abnormalities in individuals with mental retardation and congenital…”
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De novo 16p13.11 microdeletion identified by high‐resolution array CGH in a fetus with increased nuchal translucency by Law, LW, Lau, TK, Fung, TY, Leung, TY, Wang, CC, Choy, KW

“…Objective  We investigated the application of high‐resolution microarray‐based comparative genomic hybridisation (array CGH) on a fetus showing increased…”
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Trolox-equivalent antioxidant capacity assay versus oxygen radical absorbance capacity assay in plasma by CHI CHIU WANG, CHING YAN CHU, KAI ON CHU, KWONG WAI CHOY, KIM SUN KHAW, ROGERS, Michael Scott, CHI PUI PANG

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Truncations in the TIGR Gene in Individuals with and without Primary Open-Angle Glaucoma by Lam, Dennis S. C, Leung, Yuk Fai, Chua, John K. H, Baum, Larry, Fan, Dorothy S. P, Choy, Kwong Wai, Pang, Chi Pui

“…To investigate the coding exons in the trabecular meshwork-induced glucocorticoid response protein (TIGR) gene for mutations in primary open-angle glaucoma…”
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Determination of catechins and catechin gallates in tissues by liquid chromatography with coulometric array detection and selective solid phase extraction by Chu, Kai On, Wang, Chi Chiu, Chu, Ching Yan, Rogers, Michael Scott, Choy, Kwong Wai, Pang, Chi Pui

“…Catechins levels in organ tissues, particularly liver, determined by published methods are unexpectedly low, probably due to the release of oxidative enzymes,…”
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