Search Results - "Choy, Ernest"

Clinical significance of Janus Kinase inhibitor selectivity by Choy, Ernest H

“…Cytokines are key drivers of inflammation in RA, and anti-cytokine therapy has improved the outcome of RA. Janus Kinases (JAK) are intracellular tyrosine…”
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The role of sleep in pain and fibromyalgia by Choy, Ernest H. S.

“…Key Points Abnormal pain processing is an important pathophysiological feature of fibromyalgia, and nonrestorative sleep is a common clinical and diagnostic…”
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Transforming clinical trials in rheumatology: towards patient-centric precision medicine by Pitzalis, Costantino, Choy, Ernest H. S., Buch, Maya H.

“…Despite the success of targeted therapies in the treatment of inflammatory arthritides, the lack of predictive biomarkers drives a ‘trial and error’ approach…”
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C-reactive protein and implications in rheumatoid arthritis and associated comorbidities by Pope, Janet E., Choy, Ernest H.

“…•CRP is a valuable marker and regulator of systemic inflammation in RA.•CRP levels appear to be associated with common comorbidities of RA.•CRP appears to play…”
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Neuroendocrine and neurophysiological effects of interleukin 6 in rheumatoid arthritis by Choy, Ernest H S, Calabrese, Leonard H

“…Abstract RA is a chronic, systemic, autoimmune disease characterized by inflammation and degradation of the joints, causing significant negative impact on…”
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Cognitive behavioural therapies for fibromyalgia by Bernardy, Kathrin, Klose, Petra, Busch, Angela J, Choy, Ernest H S, Häuser, Winfried

“…Fibromyalgia (FM) is a clinically well-defined chronic condition of unknown aetiology characterized by chronic widespread pain that often co-exists with sleep…”
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Effect of biologics and targeted synthetic disease-modifying anti-rheumatic drugs on fatigue in rheumatoid arthritis by Choy, Ernest H

“…Abstract Fatigue is a common and debilitating symptom in patients with RA. Since 2007, fatigue has been included as one of the core outcome measures in RA…”
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Clinical significance of Janus Kinase inhibitor selectivity by Choy, Ernest H

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Non-pharmacological interventions for fatigue in rheumatoid arthritis by Cramp, Fiona, Hewlett, Sarah, Almeida, Celia, Kirwan, John R, Choy, Ernest H S, Chalder, Trudie, Pollock, Jon, Christensen, Robin

“…Fatigue is a common and potentially distressing symptom for people with rheumatoid arthritis with no accepted evidence based management guidelines…”
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Biologic interventions for fatigue in rheumatoid arthritis by Almeida, Celia, Choy, Ernest H S, Hewlett, Sarah, Kirwan, John R, Cramp, Fiona, Chalder, Trudie, Pollock, Jon, Christensen, Robin

“…Fatigue is a common and potentially distressing symptom for patients with rheumatoid arthritis (RA), with no accepted evidence-based management guidelines…”
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Translating IL-6 biology into effective treatments by Choy, Ernest H., De Benedetti, Fabrizio, Takeuchi, Tsutomu, Hashizume, Misato, John, Markus R., Kishimoto, Tadamitsu

“…In 1973, IL-6 was identified as a soluble factor that is secreted by T cells and is important for antibody production by B cells. Since its discovery more than…”
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EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors by Kostine, Marie, Finckh, Axel, Bingham, Clifton O, Visser, Karen, Leipe, Jan, Schulze-Koops, Hendrik, Choy, Ernest H, Benesova, Karolina, Radstake, Timothy R D J, Cope, Andrew P, Lambotte, Olivier, Gottenberg, Jacques-Eric, Allenbach, Yves, Visser, Marianne, Rusthoven, Cindy, Thomasen, Lone, Jamal, Shahin, Marabelle, Aurélien, Larkin, James, Haanen, John B A G, Calabrese, Leonard H, Mariette, Xavier, Schaeverbeke, Thierry

“…Rheumatic and musculoskeletal immune-related adverse events (irAEs) are observed in about 10% of patients with cancer receiving checkpoint inhibitors (CPIs)…”
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The Jak/STAT pathway: A focus on pain in rheumatoid arthritis by Simon, Lee S., Taylor, Peter C., Choy, Ernest H., Sebba, Anthony, Quebe, Amanda, Knopp, Kelly L., Porreca, Frank

“…Pain is a manifestation of rheumatoid arthritis (RA) that is mediated by inflammatory and non-inflammatory mechanisms and negatively affects quality of life…”
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Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis by Gordon, Patrick A, Winer, John B, Hoogendijk, Jessica E, Choy, Ernest H S

“…Idiopathic inflammatory myopathies are chronic diseases with significant mortality and morbidity. Whilst immunosuppressive and immunomodulatory therapies are…”
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Interleukin-6 as a Multifunctional Regulator: Inflammation, Immune Response, and Fibrosis by Choy, Ernest, Rose-John, Stefan

“…Interleukin 6 (IL-6) is a 184-amino acid protein cytokine that is produced by many types of cells and is expressed during states of cellular stress, such as…”
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Residual pain in rheumatoid arthritis: Is it a real problem? by Sarzi-Puttini, Piercarlo, Zen, Margherita, Arru, Federico, Giorgi, Valeria, Choy, Ernest A.

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Rheumatologists at a crossroads: blocking tumour necrosis factor or interleukin 6 in disease-modifying anti-rheumatic drug inadequate responder patients with rheumatoid arthritis by Quartuccio, Luca, Choy, Ernest H

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Fatigue in rheumatoid arthritis by Choy, Ernest H, Dures, Emma

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Using biologics safely by Choy, Ernest H

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Herpes Zoster and Vaccination Strategies in Inflammatory Bowel Diseases: A Practical Guide by Guillo, Lucas, Rabaud, Christian, Choy, Ernest H., D’Amico, Ferdinando, Danese, Silvio, Ng, Siew C., Peyrin-Biroulet, Laurent

“…Herpes zoster is a painful dermatomal cutaneous eruption resulting from reactivation of the latent varicella–zoster virus. Patients with inflammatory bowel…”
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