Search Results - "Chowdhury, Sabiha"

840-P: Proof of Concept of I.P. Administered Neo-Islet (NI) T1DM Biotherapy: Omentum Becomes the New Endocrine Pancreas by Spontaneous Redifferentiation of In Vitro Dedifferentiated Islet Cells by GOOCH, ANNA, CHOWDHURY, SABIHA S., WESTENFELDER, CHRISTOF

“…We published that treatment with allogeneic, species specific NIs, organoids of Mesenchymal Stromal Cells (MSCs) and culture expanded islet cells (ICs)…”
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841-P: Scientific Basis for the First-in-Human Trial of “Neo-Islet”–Mediated Functional Cure of T1DM: The Intraperitoneal Administration of “Neo-Islets,” 3-D Organoids of Allogeneic Islet and Mesenchymal Stromal Cells from Rodents, Dogs, and Humans Durably Cures by WESTENFELDER, CHRISTOF, CHOWDHURY, SABIHA S., GOOCH, ANNA

“…Initial reports from Clinical Trials with cell-based interventions for the urgently needed therapy of T1DM show: (1) An open, s.c.-placed encapsulation device…”
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760-P: Allogeneic "Neo-Islets," Organoids Composed of Cultured Pancreatic Islet and Mesenchymal Stromal Cells from Diverse Donors, Afford a Marked Increase in the Global Availability of a Curative, Novel, Anti-Rejection-Drug-Independent Biotherapy of T1DM by WESTENFELDER, CHRISTOF, CHOWDHURY, SABIHA S., GOOCH, ANNA

“…The scarcity of suitable pancreas/islet donors, the life-long need for potentially toxic anti-rejection drugs for transplants and certain biotherapies, and…”
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Significant expansion of the donor pool achieved by utilizing islets of variable quality in the production of allogeneic “Neo-Islets”, 3-D organoids of Mesenchymal Stromal and islet cells, a novel immune-isolating biotherapy for Type I Diabetes by Gooch, Anna M, Chowdhury, Sabiha S, Zhang, Ping M, Hu, Zhuma M, Westenfelder, Christof

“…Novel biotherapies for Type 1 Diabetes that provide a significantly expanded donor pool and that deliver all islet hormones without requiring anti-rejection…”
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614-P: Optimal Control of Glucose and Lipid Profiles Is Critical to the Effective “Neo-Islet” Therapy of Insulin Dependent Pet Dogs by GOOCH, ANNA, CHOWDHURY, SABIHA S., WESTENFELDER, CHRISTOF

“…We demonstrated that ip administration of “Neo-Islets” (NIs; co-aggregation of allogeneic, culture-expanded Islet cells (ICs) with Adipose derived Stem Cells…”
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262-OR: INAD 012-776 Pilot Study: Allogeneic “Neo-Islets,” Composed of Mesenchymal Stem and Islet Cells, Are Immune Protected and Dose-Dependently and Durably Control Autoimmune T1DM in Pet Dogs by WESTENFELDER, CHRISTOF, CHOWDHURY, SABIHA S., GOOCH, ANNA

“…We demonstrated that allogeneic, ip administered “Neo-Islets” (NIs), aggregates of cultured islet cells (ICs) and immune- and cyto-protective Adipose Derived…”
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204-LB: The In Vitro Characteristics of Human Islet Cells from Diverse Donors, Coaggregated with Human Mesenchymal Stromal Cells to form “Neo-islets”, Are Consistently Identical: Relevance to Clinical Trials in Diabetic Subjects by GOOCH, ANNA, CHOWDHURY, SABIHA S., ZHANG, PING, HU, ZHUMA, WESTENFELDER, CHRISTOF

“…We reported that allogeneic “Neo-Islets” (NIs), organoids composed of ~ equal numbers of Mesenchymal Stromal Cells and culture expanded Islet Cells (ICs) do,…”
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203-LB: Redosing of Suboptimally Controlled Diabetic Mice with Human Neo-islets, 3D Aggregates of Mesenchymal Stromal and Pancreatic Islet Cells, Durably Restores Euglycemia: Relevance to the Treatment of Diabetic Humans by CHOWDHURY, SABIHA S., GOOCH, ANNA, ZHANG, PING, HU, ZHUMA, WESTENFELDER, CHRISTOF

“…We reported that the i.p. administration of allogeneic Neo-Islets (NIs; 3D aggregates of allogeneic, culture-expanded Islet cells (ICs) with immune- and…”
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Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule by Poddar, Saikat Kumar, Sifat, Ali Ehsan, Haque, Sanjana, Nahid, Noor Ahmed, Chowdhury, Sabiha, Mehedi, Imtias

“…Nicotinamide mononucleotide (NMN) is a nucleotide that is most recognized for its role as an intermediate of nicotinamide adenine dinucleotide (NAD+)…”
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Paternal High Fat Diet in Rats Leads to Renal Accumulation of Lipid and Tubular Changes in Adult Offspring by Chowdhury, Sabiha S, Lecomte, Virginie, Erlich, Jonathan H, Maloney, Christopher A, Morris, Margaret J

“…Along with diabetes and obesity, chronic kidney disease (CKD) is increasing across the globe. Although some data support an effect of maternal obesity on…”
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Protein Tyrosine Phosphatase 1B and α-Glucosidase Inhibitory Phlorotannins from Edible Brown Algae, Ecklonia stolonifera and Eisenia bicyclis by MOON, Hye Eun, ISLAM, Md. Nurul, AHN, Bo Ra, CHOWDHURY, Sabiha Sultana, SOHN, Hee Sook, JUNG, Hyun Ah, CHOI, Jae Sue

“…The present work investigates protein tyrosine phosphatase 1B (PTP1B) and the α-glucosidase inhibitory activities of two edible brown algae, Ecklonia…”
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Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers by Uddin, Golam M, Youngson, Neil A, Chowdhury, Sabiha S, Hagan, Christopher, Sinclair, David A, Morris, Margaret J

“…Maternal obesity impacts offspring metabolism. We sought to boost mitochondrial energy metabolism using the nicotinamide adenine dinucleotide (NAD ) precursor…”
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Phytochemical screening and evaluation of cytotoxic and hypoglycemic properties of Mangifera indica peels by Chowdhury, Sabiha, Poddar, Saikat Kumar, Zaheen, Sarah, Noor, Farah Ashrafi, Ahmed, Najneen, Haque, Sanjana, Sukul, Abhijit, Sunjida, Sauda Binte, Mazumder, Md. Mahabob Ullah, Akbar, Nusrat

“…Objective: To investigate the presence of different phytoconstituents in Mangifera indica（M. indica） peel and evaluate its cytotoxicity to Artemia salina and…”
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Human Mesenchymal Stromal Cells Cultured in a Hollow Fiber Bioreactor Produce Constant Levels of Exosomes in the Perfusion Medium: Relevance to the Simultaneous Production of Two Biotherapeutic Agents: SA-PO019 by Westenfelder, Christof, Skliar, Mikhail, Chowdhury, Sabiha Sultana, Gooch, Anna

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Mesenchymal Stromal Cells (MSCs) Exposed to Interferon Gamma (INFγ) Secrete Exosomes (Exos) With a More Potent Renoprotective Profile Than Unexposed Cells: SA-PO020 by Gooch, Anna, Skliar, Mikhail, Chowdhury, Sabiha Sultana, Westenfelder, Christof

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Human Mesenchymal Stem Cells Cultured in a Hollow Fiber Bioreactor Maintain Constant Levels of Exosomes in the Perfusion Medium: Relevance to the Simultaneous Production of Two Biotherapeutic Agents: PO0297 by Westenfelder, Christof, Gooch, Anna, Skliar, Mikhail, Chowdhury, Sabiha Sultana, Zhang, Ping, Hu, Zhuma

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Durable Euglycemia by Intraperitoneal Administration of Allogeneic Neo-Islets, 3D Organoids of Pancreatic Islet and Mesenchymal Stem Cells, Effectively Reduces Diabetic Nephropathy in Immune-Component Non-Obese Diabetic Mice: PO0935 by Westenfelder, Christof, Gooch, Anna, Chowdhury, Sabiha Sultana, Zhang, Ping, Hu, Zhuma

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Can voluntary exercise improve renal changes in offspring induced by maternal obesity by Chowdhury, Sabiha Sultana, Bahari, Hasnah, Caruso, Vanni, Maloney, Christopher A, Morris, Margaret J

“…Abstract only Obesity in the mother is known to affect offspring, making them more prone to obesity, diabetes, and kidney disease. A recent study reported that…”
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WITHDRAWN: Phytochemical screening and evaluation of cytotoxic and hypoglycemic properties of Mangifera indica peels by Chowdhury, Sabiha, Poddar, Saikat Kumar, Zaheen, Sarah, Noor, Farah Ashrafi, Ahmed, Najneen, Haque, Sanjana, Sukul, Abhijit, Sunjida, Sauda Binte, Mazumder, Md. Mahabob Ullah, Akbar, Nusrat

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Protein Tyrosine Phosphatase 1B and [alpha]-Glucosidase Inhibitory Phlorotannins from Edible Brown Algae, Ecklonia stolonifera and Eisenia bicyclis by Eun MOON, Hye, Nurul ISLAM, Md, Ra AHN, Bo, Sultana CHOWDHURY, Sabiha, Sook SOHN, Hee, Ah JUNG, Hyun, Sue CHOI, Jae

“…The present work investigates protein tyrosine phosphatase 1B (PTP1B) and the α-glucosidase inhibitory activities of two edible brown algae, Ecklonia…”
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