Search Results - "Chowdhury, Fabliha A"
-
1
Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis
Published in The Journal of clinical investigation (15-06-2022)“…The crosstalk between the BM microenvironment (niche) and hematopoietic stem cells (HSCs) is critical for HSC regeneration. Here, we show that in mice,…”
Get full text
Journal Article -
2
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease
Published in Redox biology (01-12-2023)“…Sickle cell disease (SCD) is a hereditary hematological disease with high morbidity and mortality rates worldwide. Despite being monogenic, SCD patients…”
Get full text
Journal Article -
3
Hes1 deficiency causes hematopoietic stem cell exhaustion
Published in Stem cells (Dayton, Ohio) (01-06-2020)“…The transcriptional repressor Hairy Enhancer of Split 1 (HES1) plays an essential role in the development of many organs by promoting the maintenance of…”
Get full text
Journal Article -
4
CYB5R3 T117S tempers fetal hemoglobin induction by hydroxyurea in patients with sickle cell disease
Published in Blood advances (07-10-2024)Get full text
Journal Article -
5
Loss of Cyb5R3 Function Silences Fetal Hemoglobin and Hematocrit Responses to Hydroxyurea in Patients with Sickle Cell Anemia
Published in Blood (15-11-2022)Get full text
Journal Article -
6
Inhibition of Hypoxia Inducible Factor Prolyl Hydroxylase By FG-4592 (Roxadustat) Increases Erythropoietic Stimulation in a Mouse Model of Sickle Cell Disease
Published in Blood (15-11-2022)Get full text
Journal Article -
7
Preclinical Development and Screening of a Quinone-Nitroalkene Molecule for Sickle Cell Anemia
Published in Blood (15-11-2022)Get full text
Journal Article