Search Results - "Chowdhury, Asif Alam"
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Stability and structure-activity relationship of the SPA4 peptide under ambient and stressed conditions of lung injury
Published in RSC advances (15-06-2023)“…Lung inflammation and injuries are major health problems. The SPA4 peptide (amino acid sequence GDFRYSDGTPVNYTNWYRGE) binds to Toll-like receptor-4 and exerts…”
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Journal Article -
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Effects of SPA4 peptide on lipopolysaccharide‐disrupted lung epithelial barrier, injury, and function in a human cell system and mouse model of lung injury
Published in Physiological reports (01-07-2022)“…Disrupted epithelial barrier, fluid accumulation, inflammation, and compromised physiology are hallmarks of lung injury. Here we investigated the structural…”
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Journal Article -
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A comprehensive in vitro biological investigation of metal complexes of tolfenamic acid
Published in Alexandria journal of medicine (01-03-2018)“…The inquisitive objective of the study was to observe the antimicrobial, cytotoxicity, and antioxidant activities of some newly synthesized metal complexes of…”
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Journal Article -
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Tight Junctions, the Epithelial Barrier, and Toll-like Receptor-4 During Lung Injury
Published in Inflammation (01-12-2022)“…— Lung epithelium is constantly exposed to the environment and is critically important for the orchestration of initial responses to infectious organisms,…”
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Journal Article -
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Stability and Activity of SPA4 Peptide in Lung Injury Models
Published 01-01-2023“…Lung infections and inflammation cause lung injury. Uncontrolled lung injuries can lead to acute respiratory distress syndrome (ARDS), a life-threatening…”
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Dissertation -
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Mechanism of Anti-Inflammatory Activity of TLR4-Interacting SPA4 Peptide
Published in ImmunoHorizons (24-08-2021)“…The TLR4-interacting SPA4 peptide suppresses inflammation. We assessed the structural and physicochemical properties and binding of SPA4 peptide to TLR4-MD2…”
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Journal Article