Search Results - "Chow, Shiao"

Synthesis of N‑Sulfonyl Amidines and Acyl Sulfonyl Ureas from Sulfonyl Azides, Carbon Monoxide, and Amides by Chow, Shiao Y, Odell, Luke R

“…A Pd-catalyzed and ligand-free carbonylation/cycloaddition/decarboxylation cascade synthesis of sulfonyl amidines from sulfonyl azides and substituted amides…”
Get full text

Sulfonyl Azides as Precursors in Ligand-Free Palladium-Catalyzed Synthesis of Sulfonyl Carbamates and Sulfonyl Ureas and Synthesis of Sulfonamides by Chow, Shiao Y, Stevens, Marc Y, Odell, Luke R

“…An efficient synthesis of sulfonyl carbamates and sulfonyl ureas from sulfonyl azides employing a palladium-catalyzed carbonylation protocol has been…”
Get full text

Embarking on a Chemical Space Odyssey by Chow, Shiao Y, Nelson, Adam

“…The chemical space explored in drug discovery programs is restricted by a narrow reaction toolkit and the frequent failure of even these reactions with polar…”
Get full text

Streamlining bioactive molecular discovery through integration and automation by Chow, Shiao, Liver, Samuel, Nelson, Adam

“…The discovery of bioactive small molecules is generally driven via iterative design–make–purify–test cycles. Automation is routinely harnessed at individual…”
Get full text

Targeted Molecular Construct for Bioorthogonal Theranostics of PD-L1-Expressing Cancer Cells by Chow, Shiao Y., Unciti-Broceta, Asier

“…Molecular targeting of tumor-overexpressed oncoproteins can improve the selectivity and tolerability of anticancer therapies. The immunoinhibitory membrane…”
Get full text

Mild and Low-Pressure fac-Ir(ppy)3-Mediated Radical Aminocarbonylation of Unactivated Alkyl Iodides through Visible-Light Photoredox Catalysis by Chow, Shiao Y., Stevens, Marc Y., Åkerbladh, Linda, Bergman, Sara, Odell, Luke R.

“…A novel, mild and facile preparation of alkyl amides from unactivated alkyl iodides employing a fac‐Ir(ppy)3‐catalyzed radical aminocarbonylation protocol has…”
Get full text

Low-Pressure Radical 11C-Aminocarbonylation of Alkyl Iodides through Thermal Initiation by Chow, Shiao Y., Odell, Luke R., Eriksson, Jonas

“…A radical 11C‐aminocarbonylation protocol characterized by excellent substrate compatibility was developed to transform alkyl iodides into 11C‐labelled amides,…”
Get full text

Development of a speargun projectile penetrometer in soil by Rong, Junlin, Nazem, Majidreza, Chow, Shiao Huey, Zhou, Annan, Moridpour, Sara

“…This study investigates the applicability of a speargun projectile penetrometer (SPP) for offshore site investigation purposes using experimental testing. The…”
Get full text

Low‐Pressure Radical 11C‐Aminocarbonylation of Alkyl Iodides through Thermal Initiation by Chow, Shiao Y., Odell, Luke R., Eriksson, Jonas

Get full text

Mild and Low-Pressure fac-Ir(ppy)3-Mediated Radical Aminocarbonylation of Unactivated Alkyl Iodides through Visible-Light Photoredox Catalysis by Chow, Shiao Y., Stevens, Marc Y., Åkerbladh, Linda, Bergman, Sara, Odell, Luke R.

“…Invited for the cover of this issue is the group of L. R. Odell at Uppsala University (Sweden). The image depicts iridium at the center of a vortex of…”
Get full text

Cover Picture: Mild and Low-Pressure fac-Ir(ppy)3-Mediated Radical Aminocarbonylation of Unactivated Alkyl Iodides through Visible-Light Photoredox Catalysis (Chem. Eur. J. 27/2016) by Chow, Shiao Y., Stevens, Marc Y., Åkerbladh, Linda, Bergman, Sara, Odell, Luke R.

“…Iridium stands at the center of a vortex of electrons that are transferred to and from the surrounding reaction components in this radical aminocarbonylation…”
Get full text

A non-associative macroelement model for vertical plate anchors in clay by Peccin da Silva, Anderson, Diambra, Andrea, Karamitros, Dimitris, Chow, Shiao Huey

“…This work proposes a new plastic-hardening, non-associative macroelement model to predict the behaviour of anchors in clay for floating offshore structures…”
Get full text

Synthesis of 4H‐Benzo[e][1,3]oxazin‐4‐ones by a Carbonylation–Cyclization Domino Reaction of ortho‐Halophenols and Cyanamide by Åkerbladh, Linda, Chow, Shiao Y., Odell, Luke R., Larhed, Mats

“…A mild and convenient one‐step preparation of 4H‐1,3‐benzoxazin‐4‐ones by a domino carbonylation–cyclization process is developed. Readily available…”
Get full text

Synthesis of 4 H -Benzo[ e ][ 1,3 ]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho -Halophenols and Cyanamide by Åkerbladh, Linda, Chow, Shiao Y, Odell, Luke R, Larhed, Mats

“…-benzo[ ][ ]oxazin-4-ones. For more details, see the full text of the Full Paper at 10.1002/open.201700130…”
Get full text

Synthesis of 4 H -Benzo[ e ][ 1,3 ]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho -Halophenols and Cyanamide by Åkerbladh, Linda, Chow, Shiao Y, Odell, Luke R, Larhed, Mats

“…A mild and convenient one-step preparation of 4 -1,3-benzoxazin-4-ones by a domino carbonylation-cyclization process is developed. Readily available…”
Get full text

Synthesis of 4H‐Benzo[e][1,3]oxazin‐4‐ones by a Carbonylation–Cyclization Domino Reaction of ortho‐Halophenols and Cyanamide by Åkerbladh, Linda, Chow, Shiao Y., Odell, Luke R., Larhed, Mats

“…Invited for this month′s cover are researchers from the Division of Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala University…”
Get full text

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice by Harrison, Rosemary S, Ruiz-Gómez, Gloria, Hill, Timothy A, Chow, Shiao Y, Shepherd, Nicholas E, Lohman, Rink-Jan, Abbenante, Giovanni, Hoang, Huy N, Fairlie, David P

“…The nociceptin opioid peptide receptor (NOP, NOR, ORL-1) is a GPCR that recognizes nociceptin, a 17-residue peptide hormone. Nociceptin regulates pain…”
Get full text

Synthesis of 11C‐labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [11C]CO by Stevens, Marc Y., Chow, Shiao Y., Estrada, Sergio, Eriksson, Jonas, Asplund, Veronika, Orlova, Anna, Mitran, Bogdan, Antoni, Gunnar, Larhed, Mats, Åberg, Ola, Odell, Luke R.

“…We describe the development of a new methodology focusing on 11C‐labeling of sulfonyl carbamates in a multicomponent reaction comprised of a sulfonyl azide, an…”
Get full text

Synthesis of 11 C-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [ 11 C]CO by Stevens, Marc Y, Chow, Shiao Y, Estrada, Sergio, Eriksson, Jonas, Asplund, Veronika, Orlova, Anna, Mitran, Bogdan, Antoni, Gunnar, Larhed, Mats, Åberg, Ola, Odell, Luke R

“…We describe the development of a new methodology focusing on C-labeling of sulfonyl carbamates in a multicomponent reaction comprised of a sulfonyl azide, an…”
Get full text

A Cyclic Macro-Element Framework for Consolidation-Dependent Three-Dimensional Capacity of Plate Anchors by Peccin da Silva, Anderson, Diambra, Andrea, Karamitros, Dimitris, Chow, Shiao Huey

“…This paper presents a new macro-element modelling framework for plate anchors which enables the effect of pore water pressure changes and the related evolution…”
Get full text