Search Results - "Chow, Seong Hoong"
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A polytherapy based approach to combat antimicrobial resistance using cubosomes
Published in Nature communications (17-01-2022)“…A depleted antimicrobial drug pipeline combined with an increasing prevalence of Gram-negative ‘superbugs’ has increased interest in nano therapies to treat…”
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Intraocular Pressure Induced Retinal Changes Identified Using Synchrotron Infrared Microscopy
Published in PloS one (06-10-2016)“…Infrared (IR) spectroscopy has been used to quantify chemical and structural characteristics of a wide range of materials including biological tissues. In this…”
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Polymyxin-Induced Lipid A Deacylation in Pseudomonas aeruginosa Perturbs Polymyxin Penetration and Confers High-Level Resistance
Published in ACS chemical biology (19-01-2018)“…Polymyxins are last-line antibiotics against life-threatening multidrug-resistant Gram-negative bacteria. Unfortunately, polymyxin resistance is increasingly…”
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Polysaccharide‐Targeting Lipid Nanoparticles to Kill Gram‐Negative Bacteria
Published in Small (Weinheim an der Bergstrasse, Germany) (01-02-2024)“…The rapid increase and spread of Gram‐negative bacteria resistant to many or all existing treatments threaten a return to the preantibiotic era. The presence…”
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Coassembled Nitric Oxide-Releasing Nanoparticles with Potent Antimicrobial Efficacy against Methicillin-Resistant Staphylococcus aureus (MRSA) Strains
Published in ACS applied materials & interfaces (24-08-2022)“…Nitric oxide (NO)-releasing nanoparticles are effective nanomedicines with diverse therapeutic advantages compared with small molecule-based NO donors. Here,…”
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Defining the structural characteristics of annexin V binding to a mimetic apoptotic membrane
Published in European biophysics journal (01-12-2015)“…Annexin V is of crucial importance for detection of the phosphatidylserine of apoptotic cell membranes. However, the manner in which different amounts of…”
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