Search Results - "Chow, Sarah S."

An end-to-end workflow for nondestructive 3D pathology by Bishop, Kevin W., Erion Barner, Lindsey A., Han, Qinghua, Baraznenok, Elena, Lan, Lydia, Poudel, Chetan, Gao, Gan, Serafin, Robert B., Chow, Sarah S. L., Glaser, Adam K., Janowczyk, Andrew, Brenes, David, Huang, Hongyi, Miyasato, Dominie, True, Lawrence D., Kang, Soyoung, Vaughan, Joshua C., Liu, Jonathan T. C.

“…Recent advances in 3D pathology offer the ability to image orders of magnitude more tissue than conventional pathology methods while also providing a…”
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Energetics of Cyclic AMP Binding to HCN Channel C Terminus Reveal Negative Cooperativity by Chow, Sarah S., Van Petegem, Filip, Accili, Eric A.

“…Cyclic AMP binds to the HCN channel C terminus and variably stabilizes its open state. Using isothermal titration calorimetry, we show that cAMP binds to one…”
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Analysis of 3D pathology samples using weakly supervised AI by Song, Andrew H, Williams, Mane, Williamson, Drew F K, Chow, Sarah S L, Jaume, Guillaume, Gao, Gan, Zhang, Andrew, Chen, Bowen, Baras, Alexander S, Serafin, Robert, Colling, Richard, Downes, Michelle R, Farré, Xavier, Humphrey, Peter, Verrill, Clare, True, Lawrence D, Parwani, Anil V, Liu, Jonathan T C, Mahmood, Faisal

“…Human tissue, which is inherently three-dimensional (3D), is traditionally examined through standard-of-care histopathology as limited two-dimensional (2D)…”
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Engineering the future of 3D pathology by Liu, Jonathan TC, Chow, Sarah SL, Colling, Richard, Downes, Michelle R, Farré, Xavier, Humphrey, Peter, Janowczyk, Andrew, Mirtti, Tuomas, Verrill, Clare, Zlobec, Inti, True, Lawrence D

“…In recent years, technological advances in tissue preparation, high‐throughput volumetric microscopy, and computational infrastructure have enabled rapid…”
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Direct three-dimensional segmentation of prostate glands with nnU-Net by Wang, Rui, Chow, Sarah S. L., Serafin, Robert B., Xie, Weisi, Han, Qinghua, Baraznenok, Elena, Lan, Lydia, Bishop, Kevin W., Liu, Jonathan T. C.

“…In recent years, we and others have developed non-destructive methods to obtain three-dimensional (3D) pathology datasets of clinical biopsies and surgical…”
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Visual Assessment of 2-Dimensional Levels Within 3-Dimensional Pathology Data Sets of Prostate Needle Biopsies Reveals Substantial Spatial Heterogeneity by Koyuncu, Can, Janowczyk, Andrew, Farre, Xavier, Pathak, Tilak, Mirtti, Tuomas, Fernandez, Pedro L, Pons, Laura, Reder, Nicholas P, Serafin, Robert, Chow, Sarah S L, Viswanathan, Vidya S, Glaser, Adam K, True, Lawrence D, Liu, Jonathan T C, Madabhushi, Anant

“…Prostate cancer prognostication largely relies on visual assessment of a few thinly sectioned biopsy specimens under a microscope to assign a Gleason grade…”
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Miniature line-scanned dual-axis confocal microscope for versatile clinical use by Bishop, Kevin W, Hu, Bingwen, Vyawhare, Rajat, Yang, Zelin, Liang, David C, Gao, Gan, Baraznenok, Elena, Han, Qinghua, Lan, Lydia, Chow, Sarah S L, Sanai, Nader, Liu, Jonathan T C

“…A miniature optical-sectioning fluorescence microscope with high sensitivity and resolution would enable non-invasive and real-time tissue inspection, with…”
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In situ co-distribution and functional interactions of SAP97 with sinoatrial isoforms of HCN channels by Peters, Christian J, Chow, Sarah S, Angoli, Damiano, Nazzari, Hamed, Cayabyab, Francisco S, Morshedian, Ala, Accili, Eric A

“…Abstract The sinoatrial node is a region of specialized cardiomyocytes that is responsible for the repetitive activity of the adult heart. The sinoatrial node…”
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Regulation of cell surface expression of functional pacemaker channels by a motif in the B-helix of the cyclic nucleotide-binding domain by Nazzari, Hamed, Angoli, Damiano, Chow, Sarah S, Whitaker, Gina, Leclair, Leisha, McDonald, Evan, Macri, Vincenzo, Zahynacz, Kristin, Walker, Valerie, Accili, Eric A

“…Previous studies have suggested that a portion of the cyclic nucleotide-binding domain (CNBD) of the hyperpolarization-activated cyclic nucleotide-gated…”
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Triage of 3D pathology data via 2.5D multiple-instance learning to guide pathologist assessments by Gao, Gan, Song, Andrew H, Wang, Fiona, Brenes, David, Wang, Rui, Chow, Sarah S. L, Bishop, Kevin W, True, Lawrence D, Mahmood, Faisal, Liu, Jonathan T. C

“…Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) Workshops, 2024, pp. 6955-6965 Accurate patient diagnoses based on…”
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