Search Results - "Chow, Howard C.H."

Declined presentation by Wan, Haixia, Man, Him, Chow, Howard C.H, Chen, Fangyuan, Leung, Anskar Y.H

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Azacitidine as post-remission consolidation for sorafenib-induced remission of Fms-like tyrosine kinase-3 internal tandem duplication positive acute myeloid leukemia by Gill, Harinder, Man, Cheuk-Him, Ip, Alvin H W, Choi, William W L, Chow, Howard C H, Kwong, Yok-Lam, Leung, Anskar Y H

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FLT3 /internal tandem duplication subclones in acute myeloid leukemia differ in their engraftment potential in NOD/SCID mice by Cheung, Alice M.S, Chow, Howard C.H, Kwong, Yok-Lam, Liang, Raymond, Leung, Anskar Y.H

“…Abstract In this study, we tested if FLT3 /internal tandem duplication (ITD) in acute myeloid leukemia (AML) might occur at different hierarchical stages…”
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Successful engraftment by leukemia initiating cells in adult acute lymphoblastic leukemia after direct intrahepatic injection into unconditioned newborn NOD/SCID mice by Cheung, Alice M.S, Fung, Tsz-Kan, Fan, August K.P, Wan, Thomas S.K, Chow, Howard C.H, Leung, Joseph C.K, Chan, Loretta Y.Y, Kwong, Yok-Lam, Liang, Raymond, Leung, Anskar Y.H

“…Objective Xenogeneic transplantation has been the gold standard for enumeration of leukemia initiating cells in acute myeloid and lymphoblastic leukemia (ALL)…”
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All-trans retinoic acid induces proliferation of an irradiated stem cell supporting stromal cell line AFT024 by Cheung, Alice M.S, Tam, Chris K.H, Chow, Howard C.H, Verfaillie, Catherine M, Liang, Raymond, Leung, Anskar Y.H

“…Objective We have previously shown that all-trans retinoic acid (ATRA) enhanced the maintenance of early human hematopoietic progenitor cells (HPCs) in the…”
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Sorafenib treatment of FLT3-ITD+ acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation by Man, Cheuk Him, Fung, Tsz Kan, Ho, Christa, Han, Heron H.C., Chow, Howard C.H., Ma, Alvin C.H., Choi, William W.L., Lok, Si, Cheung, Alice M.S., Eaves, Connie, Kwong, Yok Lam, Leung, Anskar Y.H.

“…Internal tandem duplication (ITD) of the fms-related tyrosine kinase-3 (FLT3) gene occurs in 30% of acute myeloid leukemias (AMLs) and confers a poor…”
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Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia by He, Bai-Liang, Shi, Xiangguo, Man, Cheuk Him, Ma, Alvin C.H., Ekker, Stephen C., Chow, Howard C.H., So, Chi Wai Eric, Choi, William W.L., Zhang, Wenqing, Zhang, Yiyue, Leung, Anskar Y.H.

“…FMS-like tyrosine kinase 3 (FLT3) is expressed in human hematopoietic stem and progenitor cells (HSPCs) but its role during embryogenesis is unclear. In acute…”
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A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML by Man, Cheuk Him, Lam, Stephen S.Y., Sun, Murphy K.H., Chow, Howard C.H., Gill, Harinder, Kwong, Yok Lam, Leung, Anskar Y.H.

“…Internal tandem duplication (ITD) of fms-like tyrosine kinase 3 (FLT3) in acute myeloid leukemia (AML) is associated with inferior clinical prognosis…”
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Declined presentation: Sox7 was highly expressed in cd34+ cells and promoted the leukemogenesis of all by Wan, Haixia, Man, Him, Chow, Howard C.H., Chen, Fangyuan, Leung, Anskar Y.H.

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Whole Genome Sequencing On Donor Cell Leukemia in a Patient with Multiple Myeloma Identified Gene Mutations That May Provide Insights to Leukemogenesis by Ho, Eric S.K., Chow, Howard C.H., Chan, Chris T.L., Luo, Ruibang, Leung, Henry C.M., Yiu, Siu Ming, Chin, Francis Y.L., Kwong, Yok Lam, Leung, Anskar Y.H.

“…Abstract 2414 Donor cell leukemia (DCL) is a rare occurrence and refers to leukemia of donor origin in patients who have received allogeneic hematopoietic stem…”
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Lineage-Specific Sox7 Expression In Hematopoietic Progenitor Cells Derived From Human Umbilical Cord Blood by Wan, HaiXia, Chow, Howard C.H., Fung, Tsz-Kan, Fan, Kin-Pong, Wong, Anders S.Y., Liang, Raymond, Leung, Anskar Y.H.

“…Abstract 4781 The SOX (Sry-related HMG box) genes belong to a family of transcription factors containing a High-Mobility-Group box domain. In an initial screen…”
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Downregulation of SOX7 by DNA Methylation and Its Tumor Suppressing Role In Acute Myeloid Leukemia by Fung, Tsz-Kan, Fan, Kin-Pong, Wan, HaiXia, Chow, Howard C.H., Wong, Anders S.Y., Wan, Tommas S.K., Kwong, Yok Lam, Liang, Raymond, Leung, Anskar Y.H.

“…Abstract 4189 The SOX (Sry-related HMG box) gene family is a group of transcription factors containing in common a High-Mobility-Group (HMG) box domain which…”
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Human Myeloma Cells Undergo Differentiation and Apoptosis upon Exposure of Rosiglitazone and All-Trans Retinoic Acid Via Apoptosis Signaling Pathway Modulation by Huang, Haiwen, Depei, Wu, Chen, Guanghua, Chang, Weirong, Leung, Anska Y.H., Liang, Raymond, Chow, Howard C.H.

“…Background Myeloma cells often develop drug resistance leading to treatment failure in the patients. New agents that can overcome drug resistance through…”
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A comparative study of bone marrow and peripheral blood CD34+ myeloblasts in acute myeloid leukaemia by Cheung, Alice M. S., Chow, Howard C. H., Liang, Raymond, Leung, Anskar Y. H.

“…Summary To examine the differences between primitive bone marrow (BM) and peripheral blood (PB) myeloblasts in acute myeloid leukaemia (AML), we compared CD34+…”
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The use of human induced pluripotent stem cells (hiPSC) for modeling blood disorders by Chow, Howard C.H., Cheung, Alice M.S., Li, Ronald A., Chan, Camie W.Y., So, Eric C.W., Leung, Anskar Y.H.

“…Recent advances in cellular reprogramming and stem cell biology have opened up unique opportunities in regenerative medicine, gene therapy and disease…”
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All-trans retinoic acid can intensify the growth inhibition and differentiation induction effect of rosiglitazone on multiple myeloma cells by Huang, Haiwen, Wu, Depei, Fu, Jinxiang, Chen, Guanghua, Chang, Weirong, Chow, Howard C. H., Leung, Anskar Y. H., Liang, Raymond

“…Objective:  Activation of PPARγ by its ligands has shown potential anti‐neoplastic effects in solid tumors. In this study, we investigate the effects of…”
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Genetic polymorphism in exon 4 of cytochrome P450 CYP2C9 may be associated with warfarin sensitivity in Chinese patients by Leung, Anskar Y.H., Chow, Howard C.H., Kwong, Y.L., Lie, Albert K.W., Fung, Alvin T.K., Chow, W.H., Yip, Alex S.B., Liang, Raymond

“…CYP2C9 polymorphisms reported in Caucasians (Arg144Cys in exon 3 and Ile359Leu in exon 7) are extremely uncommon in Chinese persons. The genotype of CYP2C9 in…”
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Influence of rosiglitazone and all-trans-retinoic acid on angiogenesis and growth of myeloma xenograft in nude mice by Huang, Hai-wen, Chen, Ping, Li, Bing-zong, Fu, Jin-xiang, Li, Jun, Zhang, Xiao-hui, Liu, Rui, Fan, Yin-yin, Zhang, Hong, Chow, Howard C H, Leung, Anska Y H, Liang, Raymond

“…To observe the effect of rosiglitazone (RGZ) and all-trans-retinoic acid (ATRA) on the growth of myeloma xenograft in nude mice and to explore the influence of…”
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Differentiating effect of PPARgamma ligand rosiglitazone and all trans-retinoic acid on myeloma cells and its possible mechanism by Huang, Hai-wen, Chen, Guang-hua, Chang, Hui-rong, Chow, Howard C H, Leung, Anska Y H, Liang, Raymond, Wu, De-pei

“…To investigate the effects of PPARgamma ligand (rosiglitazone, RGZ) as well as combined with all trans-retinoic acid (ATRA) on human myeloma cells and try to…”
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