Search Results - "Chourasia, Manish K."
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Nanoemulsion: Concepts, development and applications in drug delivery
Published in Journal of controlled release (28-04-2017)“…Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or oil in water (O/W) droplets stabilized by an amphiphilic…”
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Engineered nanocrystal technology: In-vivo fate, targeting and applications in drug delivery
Published in Journal of controlled release (10-06-2014)“…Formulation of nanocrystals is a robust approach which can improve delivery of poorly water soluble drugs, a challenge pharmaceutical industry has been facing…”
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Targeting tumor associated macrophages (TAMs) via nanocarriers
Published in Journal of controlled release (28-05-2017)“…Recruitment of inflammatory cells to tumor has been well documented, with the most frequent inhabitants being macrophages termed as tumor associated…”
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Targeting of gastrointestinal tract for amended delivery of protein/peptide therapeutics: Strategies and industrial perspectives
Published in Journal of controlled release (28-12-2014)“…Delivery of proteins/peptides to the gastrointestinal (GI) tract via peroral/oral route involves tremendous challenges due to unfavorable environmental…”
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Immunoadjuvant Chemotherapy of Visceral Leishmaniasis in Hamsters Using Amphotericin B-Encapsulated Nanoemulsion Template-Based Chitosan Nanocapsules
Published in Antimicrobial Agents and Chemotherapy (01-04-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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LC-MS/MS method for simultaneous estimation of raloxifene, cladrin in rat plasma: application in pharmacokinetic studies
Published in Bioanalysis (01-02-2024)“…A newer LC-MS/MS method was developed and validated for the simultaneous quantification of raloxifene (RL) and cladrin (CL). Both drugs were resolved in RP-18…”
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Bioinspired Calcium Phosphate Nanoparticles Featuring as Efficient Carrier and Prompter for Macrophage Intervention in Experimental Leishmaniasis
Published in Pharmaceutical research (01-11-2016)“…Purpose To develop a biocompatible and bioresorbable calcium phosphate (CaP) nanoparticles (NPs) bearing Amphotericin B (AmB) with an aim to provide macrophage…”
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Perspectives of nanoemulsion assisted oral delivery of docetaxel for improved chemotherapy of cancer
Published in Drug delivery (12-02-2016)“…Nanoemulsions (NE) are one of the robust delivery tools for drugs due to their higher stability and efficacy. The purpose of present investigation is to…”
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Cross-linked guar gum microspheres: a viable approach for improved delivery of anticancer drugs for the treatment of colorectal cancer
Published in AAPS PharmSciTech (08-09-2006)“…In the present work, guar gum microspheres containing methotrexate (MTX) were prepared and characterized for local release of drug in the colon, which is a…”
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Chitosan-based macrophage-mediated drug targeting for the treatment of experimental visceral leishmaniasis
Published in Journal of microencapsulation (01-06-2011)“…The potential of chitosan microparticles as a carrier of doxorubicin for the treatment of visceral leishmaniasis was evaluated by macrophage-mediated drug…”
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Dendrimer nanohybrid carrier systems: an expanding horizon for targeted drug and gene delivery
Published in Drug discovery today (01-02-2018)“…•Dendrimer-based hybrid systems are an emerging platform in the field of drug delivery.•Hybrid nanomaterials are an important strategy in the field of…”
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Nanocosmeceuticals: Trends and Recent Advancements in Self Care
Published in AAPS PharmSciTech (29-02-2024)“…The term cosmetics refers to any substances or products intended for external application on the skin with the aim of protection and better appearance of the…”
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Therapeutic targeting of Wnt antagonists by small molecules for treatment of osteoporosis
Published in Biochemical pharmacology (01-12-2024)“…[Display omitted] Wnt signaling is one of the key regulators of bone development and homeostasis. Wnt signaling regulates key biological events, including stem…”
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Enhanced apoptotic and anticancer potential of paclitaxel loaded biodegradable nanoparticles based on chitosan
Published in International journal of biological macromolecules (01-05-2017)“…Taxanes have established and proven effectivity against different types of cancers; in particular breast cancers. However, the high hemolytic toxicity and…”
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Lessons Learned from Gemcitabine: Impact of Therapeutic Carrier Systems and Gemcitabine's Drug Conjugates on Cancer Therapy
Published in Critical reviews in therapeutic drug carrier systems (2017)“…Currently, drug delivery systems have a high impact in cancer therapy and are receiving more attention than conventional cancer treatment modalities. Compared…”
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Inhalable Particles Containing Rapamycin for Induction of Autophagy in Macrophages Infected with Mycobacterium tuberculosis
Published in Molecular pharmaceutics (07-04-2014)“…We investigated whether particles suitable for delivery to alveolar macrophages may provide a means of targeting rapamycin, an inducer of autophagy, to…”
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Recent Advancements in Nanocarrier-assisted Brain Delivery of Phytochemicals Against Neurological Diseases
Published in Neurochemical research (01-10-2023)“…Despite ongoing advancements in research, the inability of therapeutics to cross the blood–brain barrier (BBB) makes the treatment of neurological disorders…”
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Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin
Published in International journal of biological macromolecules (01-02-2019)“…Immunotherapeutic nanoparticles (NPs) could be a viable option for delivering cytotoxic agents in a manner which suppresses their toxic manifestations…”
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Enhanced oral bioavailability of levormeloxifene and raloxifene by nanoemulsion: simultaneous bioanalysis using liquid chromatography-tandem mass spectrometry
Published in Nanomedicine (London, England) (2024)“…Levormeloxifene (L-ORM) and raloxifene (RAL) are selective estrogen receptor modulators used in the treatment of postmenopausal osteoporosis and breast cancer…”
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The Neoteric Paradigm of Biomolecule-Functionalized Albumin-Based Targeted Cancer Therapeutics
Published in AAPS PharmSciTech (05-11-2024)“…Albumin is a nature-derived, versatile protein carrier, that has been explored extensively by researchers for anticancer drug delivery due to its role in…”
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