Identifying women with increased risk of breast cancer and implementing risk-reducing strategies and supplemental imaging

Identifying women with increased risk of breast cancer and implementing risk-reducing strategies and supplemental imaging

Breast cancer (BC) is the second most common cancer in women, affecting 1 in 8 women in the United States (12.5%) in their lifetime. However, some women have a higher lifetime risk of BC because of genetic and lifestyle factors, mammographic breast density, and reproductive and hormonal factors. Bec...

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Bibliographic Details
Published in:Breast cancer (Tokyo, Japan) Vol. 29; no. 1; pp. 19 - 29
Main Authors: Vegunta, Suneela, Bhatt, Asha A., Choudhery, Sadia A., Pruthi, Sandhya, Kaur, Aparna S.
Format: Journal Article
Language:English
Published: Singapore Springer Singapore 2022
Springer
Subjects:
Breast cancer
Breast Density
Breast Neoplasms - etiology
Breast Neoplasms - prevention & control
Cancer Research
Diagnostic Imaging - methods
Early Detection of Cancer
Female
Genetic Counseling
Genetic Predisposition to Disease
Health aspects
Humans
Life Style
Mammography
Medicine
Medicine & Public Health
Menarche
Menopause
Oncology
Practice Guidelines as Topic
Primary Prevention
Review Article
Risk Assessment
Risk Factors
Surgery
Surgical Oncology
Women
BRCA
Dense breast tissue
Breast MRI
Risk factors for breast cancer
Risk-assessment models
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Summary:Breast cancer (BC) is the second most common cancer in women, affecting 1 in 8 women in the United States (12.5%) in their lifetime. However, some women have a higher lifetime risk of BC because of genetic and lifestyle factors, mammographic breast density, and reproductive and hormonal factors. Because BC risk is variable, screening and prevention strategies should be individualized after considering patient-specific risk factors. Thus, health care professionals need to be able to assess risk profiles, identify high-risk women, and individualize screening and prevention strategies through a shared decision-making process. In this article, we review the risk factors for BC, risk-assessment models that identify high-risk patients, and preventive medications and lifestyle modifications that may decrease risk. We also discuss the benefits and limitations of various supplemental screening methods.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1340-6868
1880-4233
DOI:10.1007/s12282-021-01298-x