Search Results - "Choudhary, Shailesh K."

Tick bite-induced alpha-gal syndrome and immunologic responses in an alpha-gal deficient murine model by Sharma, Surendra Raj, Choudhary, Shailesh K, Vorobiov, Julia, Commins, Scott P, Karim, Shahid

“…Alpha-Gal Syndrome (AGS) is a delayed allergic reaction due to specific IgE antibodies targeting galactose-α-1,3-galactose (α-gal), a carbohydrate found in red…”
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Generation of HIV Latency in Humanized BLT Mice by DENTON, Paul W, OLESEN, Rikke, MARGOLIS, David M, GARCIA, J. Victor, CHOUDHARY, Shailesh K, ARCHIN, Nancy M, WAHL, Angela, SWANSON, Michael D, CHATEAU, Morgan, NOCHI, Tomonori, KRISKO, John F, SPAGNUOLO, Rae Ann

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T and B Lymphocyte Transcriptional States Differentiate between Sensitized and Unsensitized Individuals in Alpha-Gal Syndrome by Iweala, Onyinye I, Choudhary, Shailesh K, Addison, Claire T, Commins, Scott P

“…The mechanisms of pathogenesis driving alpha-gal syndrome (AGS) are not fully understood. Differences in immune gene expression between AGS individuals and…”
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Targeted cytotoxic therapy kills persisting HIV infected cells during ART by Denton, Paul W, Long, Julie M, Wietgrefe, Stephen W, Sykes, Craig, Spagnuolo, Rae Ann, Snyder, Olivia D, Perkey, Katherine, Archin, Nancie M, Choudhary, Shailesh K, Yang, Kuo, Hudgens, Michael G, Pastan, Ira, Haase, Ashley T, Kashuba, Angela D, Berger, Edward A, Margolis, David M, Garcia, J Victor

“…Antiretroviral therapy (ART) can reduce HIV levels in plasma to undetectable levels, but rather little is known about the effects of ART outside of the…”
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Curing HIV: Pharmacologic Approaches to Target HIV-1 Latency by CHOUDHARY, Shailesh K, MARGOLIS, David M

“…HIV-1 infection persists even after years of antiretroviral therapy (ART). Although ART can halt viral replication and thereby reduce viremia to clinically…”
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Latent HIV-1 Infection of Resting CD4+ T Cells in the Humanized Rag2−/− γc−/− Mouse by CHOUDHARY, Shailesh K, ARCHIN, Nancie M, CHEEMA, Manzoor, DAHL, Noelle P, GARCIA, J. Victor, MARGOLIS, David M

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Association of Alpha-gal Red Meat Allergy Severity with Concentration of Antigen in Basophil Activation by Choudhary, Shailesh K., PhD, Commins, Scott P., MD, PhD

“…Conclusions Patients with delayed anaphylaxis to red meat present a novel disease with late onset break in oral tolerance, no immediate symptoms of food…”
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Tick salivary gland extract induces alpha‐gal syndrome in alpha‐gal deficient mice by Choudhary, Shailesh K., Karim, Shahid, Iweala, Onyinye I., Choudhary, Shivangi, Crispell, Gary, Sharma, Surendra Raj, Addison, Claire T., Kulis, Mike, Herrin, Brian H., Little, Susan E., Commins, Scott P.

“…Introduction Alpha‐gal syndrome (AGS) is characterized by delayed hypersensitivity to non‐primate mammalian meat in people having specific immunoglobulin E…”
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Hexamethylbisacetamide and Disruption of Human Immunodeficiency Virus Type 1 Latency in CD4+ T Cells by Choudhary, Shailesh K., Archin, Nancy M., Margolis, David M.

“…BackgroundNovel therapeutic approaches are needed to attack persistent proviral human immunodeficiency type 1 (HIV-1) infection. Hexamethylbisacetamide (HMBA),…”
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Suppression of Human Immunodeficiency Virus Type 1 (HIV-1) Viremia with Reverse Transcriptase and Integrase Inhibitors, CD4+ T-Cell Recovery, and Viral Rebound upon Interruption of Therapy in a New Model for HIV Treatment in the Humanized Rag2−/−γc−/− Mouse by CHOUDHARY, Shailesh K, REZK, Naser L, INCE, William L, CHEEMA, Manzoor, LIGUO ZHANG, LISHAN SU, SWANSTROM, Ronald, KASHUBA, Angela D. M, MARGOLIS, David M

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Low Immune Activation despite High Levels of Pathogenic Human Immunodeficiency Virus Type 1 Results in Long-Term Asymptomatic Disease by CHOUDHARY, Shailesh K, VRISEKOOP, Nienke, JANSEN, Christine A, OTTO, Sigrid A, SCHUITEMAKER, Hanneke, MIEDEMA, Frank, CAMERMI, David

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Human Immunodeficiency Virus Type 1 Vpr-Mediated G2 Arrest Requires Rad17 and Hus1 and Induces Nuclear BRCA1 and γ-H2AX Focus Formation by Zimmerman, Erik S., Chen, Junjie, Andersen, Joshua L., Ardon, Orly, DeHart, Jason L., Blackett, Jana, Choudhary, Shailesh K., Camerini, David, Nghiem, Paul, Planelles, Vicente

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Food Allergy by Iweala, Onyinye I., Choudhary, Shailesh K., Commins, Scott P.

“…Purpose of Review The goal of this review is to present an updated summary of the natural history of major childhood and adult food allergies and report recent…”
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Allergic response to medical products in patients with alpha-gal syndrome by Kuravi, Kasinath V., Sorrells, Lori T., Nellis, Joseph R., Rahman, Farzana, Walters, Anneke H., Matheny, Robert G., Choudhary, Shailesh K., Ayares, David L., Commins, Scott P., Bianchi, John R., Turek, Joseph W.

“…Galactose-α-1,3-galactose (alpha-gal) is a carbohydrate that is ubiquitously expressed in all mammals except for primates and humans. Patients can become…”
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Development of anti-PEG IgG/IgM/IgE ELISA assays for profiling anti-PEG immunoglobulin response in PEG-sensitized individuals and patients with alpha-gal allergy by Li, Zhongbo, Ma, Alice, Miller, Ian, Starnes, Rachel, Talkington, Anne, Stone, Cosby A., Phillips, Elizabeth J., Choudhary, Shailesh K., Commins, Scott P., Lai, Samuel K.

“…Polyethylene glycol (PEG) is frequently used in various protein and nanomedicine therapeutics. However, various studies have shown that select PEGylated…”
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Identification of Alpha-Gal glycolipids in saliva of Lone-Star Tick (Amblyomma americanum) by Sharma, Surendra Raj, Hussain, Sabir, Choudhary, Shailesh K., Commins, Scott P., Karim, Shahid

“…Alpha-Gal Syndrome (AGS) is a delayed allergic reaction triggered by IgE antibodies targeting galactose-α-1,3-galactose (α-gal), prevalent in red meat. Its…”
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Glycolipid-mediated basophil activation in alpha-gal allergy by Iweala, Onyinye I., Choudhary, Shailesh K., Addison, Claire T., Batty, Cole J., Kapita, Camille M., Amelio, Claire, Schuyler, Alexander J., Deng, Shenglou, Bachelder, Eric M., Ainslie, Kristy M., Savage, Paul B., Brennan, Patrick J., Commins, Scott P.

“…Alpha-gal-containing glycolipids activate basophils sensitized with plasma from alpha-gal allergic subjects in an IgE-dependent manner suggesting a role for…”
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Tick bite as a risk factor for alpha-gal–specific immunoglobulin E antibodies and development of alpha-gal syndrome by Kersh, Gilbert J., Salzer, Johanna, Jones, Emma S., Binder, Alison M., Armstrong, Paige A., Choudhary, Shailesh K., Commins, Grace K., Amelio, Claire L., Kato, Cecilia Y., Singleton, Joseph, Biggerstaff, Brad J., Beard, Charles B., Petersen, Lyle R., Commins, Scott P.

“…The disaccharide galactose-α-1,3-galactose (alpha-gal) is expressed in mammals other than humans, apes, and old-world monkeys. In humans, elevated…”
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Intrinsic risk factors for alpha-gal syndrome in a case-control study, 2019 to 2020 by Taylor, Marissa L., Kersh, Gilbert J., Salzer, Johanna S., Jones, Emma S., Binder, Alison M., Armstrong, Paige A., Choudhary, Shailesh K., Commins, Grace K., Amelio, Claire L., Biggerstaff, Brad J., Beard, Charles B., Petersen, Lyle R., Commins, Scott P.

“…Alpha-gal syndrome (AGS) is an allergy to galactose-α-1,3-galactose (alpha-gal), a carbohydrate found in most mammals. Evidence indicates that AGS develops…”
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R5 Human Immunodeficiency Virus Type 1 Infection of Fetal Thymic Organ Culture Induces Cytokine and CCR5 Expression by CHOUDHARY, Shailesh K, CHOUDHARY, Neelima R, KIMBRELL, Katherine C, COLASANTI, Jonathan, ZIOGAS, Argyrios, KWA, David, SCHUITEMAKER, Hanneke, CAMERINI, David

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