Search Results - "Choudhary, Nishant Kumar"
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N3-Methyluridine and 2′-O-Alkyl/2′-Fluoro-N3-methyluridine functionalized nucleic acids improve nuclease resistance while maintaining duplex geometry
Published in Bioorganic & medicinal chemistry (15-02-2024)“…Oligonucleotides containing chemical modification including m3U and 2′-O-alkyl substituted m3U with increasing chain length (methyl to propyl/MOE) were…”
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MXene-based aptasensor for the detection of aflatoxin in food and agricultural products
Published in Environmental pollution (1987) (01-01-2023)“…The detection of toxins that contaminate food needs highly sensitive and selective techniques to prevent substantial monitory loss. In this regard, various…”
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Internet-of-things-integrated molecularly imprinted polymer-based electrochemical nano-sensors for pesticide detection in the environment and food products
Published in Environmental pollution (1987) (15-06-2024)“…To ensure environmental and health safety, relevant pollutants such as pesticides must be screened thoroughly to set their permissible limit. Various…”
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Selective Recognition of the Dimeric NG16 Parallel G‑Quadruplex Structure Using Synthetic Turn-On Red Fluorescent Protein Chromophore
Published in Biochemistry (Easton) (05-11-2024)“…Red fluorescent protein (RFP)-based fluorescent probes that can selectively interact with specific nucleic acids are of great importance for therapeutic and…”
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Plant-based bioactive molecules for targeting of endoribonuclease using steered molecular dynamic simulation approach: a highly conserved therapeutic target against variants of SARS-CoV-2
Published in Molecular simulation (13-08-2023)“…The lesser side effects and proven therapeutic efficacy of plant bioactive compounds (phytochemicals) have made them the drug of choice in the current COVID-19…”
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Synthesis and Structural Analysis of N3‐Methyluridine and 2’‐Alkoxy/Fluoro‐N3‐Methyluridine Nucleosides by Using NMR Spectroscopy, X‐Ray Crystallography, and Computational Methods
Published in ChemistrySelect (Weinheim) (26-06-2023)“…Dual modifications (base and sugar) in siRNA have the potential to overcome off‐target effects and impart nuclease resistance. Here we present the synthesis…”
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Green Synthesis of CdS and CdS/rGO Nanocomposites: Evaluation of Electrochemical, Antimicrobial, and Photocatalytic Properties
Published in ACS applied bio materials (18-09-2023)“…The green approach has been employed for the synthesis of various types of nanomaterials including metal nanoparticles, metal oxides, and carbon-based…”
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Synthesis and Structural Analysis of N 3 ‐Methyluridine and 2’‐Alkoxy/Fluoro‐ N 3 ‐Methyluridine Nucleosides by Using NMR Spectroscopy, X‐Ray Crystallography, and Computational Methods
Published in ChemistrySelect (Weinheim) (26-06-2023)“…Abstract Dual modifications (base and sugar) in siRNA have the potential to overcome off‐target effects and impart nuclease resistance. Here we present the…”
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N 3 -Methyluridine and 2'-O-Alkyl/2'-Fluoro-N 3 -methyluridine functionalized nucleic acids improve nuclease resistance while maintaining duplex geometry
Published in Bioorganic & medicinal chemistry (15-02-2024)“…Herein, we report the synthesis of 2'-O-alkyl/2'-fluoro-N -methyluridine (2'-O-alkyl/2'-F-m U) phosphoramidites and their incorporation in DNA and RNA…”
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