Search Results - "Chou, Wen‐Cheng"

ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study by Chen, Chung-Jen, Tseng, Chia-Chun, Yen, Jeng-Hsien, Chang, Jan-Gowth, Chou, Wen-Cheng, Chu, Hou-Wei, Chang, Shun-Jen, Liao, Wei-Ting

“…Although many genome-wide association studies (GWASs) of hyperuricemia or gout have been reported, the related genetic factors and the mechanisms from…”
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A functional variant near XCL1 gene improves breast cancer survival via promoting cancer immunity by Chou, Wen‐Cheng, Hsiung, Chia‐Ni, Chen, Wei‐Ting, Tseng, Ling‐Ming, Wang, Hui‐Chun, Chu, Hou‐Wei, Hou, Ming‐Feng, Yu, Jyh‐Cherng, Shen, Chen‐Yang

“…Most genome‐wide association studies (GWASs) identify genetic variants for breast cancer occurrence. In contrast, few are for recurrence and mortality. We…”
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Development of a Wearable Instrumented Vest for Posture Monitoring and System Usability Verification Based on the Technology Acceptance Model by Lin, Wen-Yen, Chou, Wen-Cheng, Tsai, Tsai-Hsuan, Lin, Chung-Chih, Lee, Ming-Yih

“…Body posture and activity are important indices for assessing health and quality of life, especially for elderly people. Therefore, an easily wearable device…”
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The Causal Relationship of Circulating Triglyceride and Glycated Hemoglobin: A Mendelian Randomization Study by Hsiung, Chia-Ni, Chang, Yi-Cheng, Lin, Chien-Wei, Chang, Chia-Wei, Chou, Wen-Cheng, Chu, Hou-Wei, Su, Ming-Wei, Wu, Pei-Ei, Shen, Chen-Yang

“…Abstract Context The association between circulating triglyceride (TG) and glycated hemoglobin A1c (HbA1c), a biomarker for type 2 diabetes, has been widely…”
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The Effect of MicroRNA-124 Overexpression on Anti-Tumor Drug Sensitivity by Chen, Shiau-Mei, Chou, Wen-Cheng, Hu, Ling-Yueh, Hsiung, Chia-Ni, Chu, Hou-Wei, Huang, Yuan-Ling, Hsu, Huan-Ming, Yu, Jyh-Cherng, Shen, Chen-Yang

“…MicroRNAs play critical roles in regulating various physiological processes, including growth and development. Previous studies have shown that microRNA-124…”
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Realization and Technology Acceptance Test of a Wearable Cardiac Health Monitoring and Early Warning System with Multi-Channel MCGs and ECG by Lin, Wen-Yen, Ke, Hong-Lin, Chou, Wen-Cheng, Chang, Po-Cheng, Tsai, Tsai-Hsuan, Lee, Ming-Yih

“…In this work, a wearable smart clothing system for cardiac health monitoring with a multi-channel mechanocardiogram (MCG) has been developed to predict the…”
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Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer by Chou, Wen-Cheng, Chen, Wei-Ting, Kuo, Chun-Tse, Chang, Yao-Ming, Lu, Yen-Shen, Li, Chia-Wei, Hung, Mien-Chie, Shen, Chen-Yang

“…Immune checkpoint blockade (ICB) is a promising therapy for solid tumors, but its effectiveness depends on biomarkers that are not precise. Here, we utilized…”
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A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4 by Chou, Wen-Cheng, Chen, Wei-Ting, Shen, Chen-Yang

“…Large-scale genome-wide associations comprising multiple studies have identified hundreds of genetic loci commonly associated with hyperlipidemia-related…”
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Identification of Location Specific Feature Points in a Cardiac Cycle Using a Novel Seismocardiogram Spectrum System by Lin, Wen-Yen, Tsai, Tsai-Hsuan, Lee, Ming-Yih, Chou, Wen-Cheng, Chang, Po-Cheng, Chou, Chung-Chuan, Wen, Ming-Shien, Ho, Ming-Yun, Lee, Wen-Chen, Hsieh, Ming-Jer, Lin, Chung-Chih

“…Seismocardiogram (SCG) or mechanocardiography is a noninvasive cardiac diagnostic method; however, previous studies used only a single sensor to detect cardiac…”
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B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers by Chou, Wen-Cheng, Chen, Wei-Ting, Hsiung, Chia-Ni, Hu, Ling-Yueh, Yu, Jyh-Cherng, Hsu, Huan-Ming, Shen, Chen-Yang

“…The key signature of cancer genomes is the accumulation of DNA mutations, the most abundant of which is the cytosine-to-thymine (C-to-T) transition that…”
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Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro by Huang, Hsiang-Chi, Lai, Yun-Ju, Liao, Chun-Che, Yang, Wang-Feng, Huang, Ke-Bin, Lee, I-Jung, Chou, Wen-Cheng, Wang, Shih-Han, Wang, Ling-Hui, Hsu, Jung-Mao, Sun, Cheng-Pu, Kuo, Chun-Tse, Wang, Jyun, Hsiao, Tzu-Chun, Yang, Po-Jiun, Lee, Te-An, Huang, Wilson, Li, Fu-An, Shen, Chen-Yang, Lin, Yi-Ling, Tao, Mi-Hua, Li, Chia-Wei

“…Despite clinical success with anti-spike vaccines, the effectiveness of neutralizing antibodies and vaccines has been compromised by rapidly spreading…”
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Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair by Chou, Wen-Cheng, Wang, Hui-Chun, Wong, Fen-Hwa, Ding, Shian-ling, Wu, Pei-Ei, Shieh, Sheau-Yann, Shen, Chen-Yang

“…The DNA damage response (DDR) has an essential function in maintaining genomic stability. Ataxia telangiectasia‐mutated (ATM)‐checkpoint kinase 2 (Chk2) and…”
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SUMOylation of XRCC1 activated by poly (ADP-ribosyl)ation regulates DNA repair by Hu, Ling-Yueh, Chang, Che-Chang, Huang, Yen-Sung, Chou, Wen-Cheng, Lin, Ying-Mei, Ho, Chun-Chen, Chen, Wei-Ting, Shih, Hsiu-Ming, Hsiung, Chia-Ni, Wu, Pei-Ei, Shen, Chen-Yang

“…Abstract XRCC1 is an essential scaffold protein for base excision repair (BER) and helps to maintain genomic stability. XRCC1 has been indicated as a substrate…”
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Dynamic Deformation Behaviour and Dislocation Substructure of AZ80 Magnesium Alloy over a Wide Range of Temperatures by Lee, Woei-Shyan, Chou, Cheng-Wen

“…The high strain rate deformation behaviour and dislocation substructure of AZ80 magnesium alloy are investigated at strain rates of 8x102 s-1, 1.5x103 s-1 and…”
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Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining by WANG, Hui-Chun, CHOU, Wen-Cheng, SHIEH, Sheau-Yann, SHEN, Chen-Yang

“…Homologous recombination (HR) and nonhomologous end-joining (NHEJ) are the two mechanisms responsible for repairing DNA double-strand breaks (DSBs) and act in…”
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Severinia buxifolia-isolated acridones inhibit lung cancer invasion and decrease HIFα protein synthesis involving 5’UTR-mediated translation inhibition by Chen, Pin-Wei, Huang, Sheng-Kai, Chou, Wen-Cheng, Chang, Fang-Rong, Cheng, Yuan-Bin, Wang, Hui-Chun

“…Lung cancer is one of the most common cancers worldwide and is by far the leading cause of cancer death attributed to its rapid metastasis and poor prognosis…”
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Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway by Chou, Wen-Cheng, Hu, Ling-Yueh, Hsiung, Chia-Ni, Shen, Chen-Yang

“…The DNA damage response (DDR) is activated by various genotoxic stresses. Base lesions, which are structurally simple and predominantly fixed by base excision…”
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A digital tilt converter for three-axis accelerometers by Chun-Liang Hsu, Wen-Cheng Chou, Wen-Yen Lin

“…Three-axis accelerometers have been widely used not only in motion sensing but also in tilting sensing nowadays. The tilting angle conversions from 3D…”
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A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis by Chu, Hou-Wei, Cheng, Chun-Wen, Chou, Wen-Cheng, Hu, Ling-Yueh, Wang, Hsiao-Wei, Hsiung, Chia-Ni, Hsu, Huan-Ming, Wu, Pei-Ei, Hou, Ming-Feng, Shen, Chen-Yang, Yu, Jyh-Cherng

“…To identify microRNAs that are important in regulating breast cancer progression, the present study used data for the 199 961 single-nucleotide polymorphisms…”
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Tumorigenic and Metastatic Role of CD44 -/low /CD24 -/low Cells in Luminal Breast Cancer by Vikram, Rajeev, Chou, Wen Cheng, Hung, Shih-Chieh, Shen, Chen-Yang

“…Cells with high CD44 but low CD24 expression (CD44 /CD24 ) and high aldehyde dehydrogenase activity (ALDH ) are widely considered to be drivers of metastasis,…”
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