Search Results - "Chou, Tristan"
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LncRNA Jpx induces Xist expression in mice using both trans and cis mechanisms
Published in PLoS genetics (07-05-2018)“…Mammalian X chromosome dosage compensation balances X-linked gene products between sexes and is coordinated by the long noncoding RNA (lncRNA) Xist. Multiple…”
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A cancer-associated RNA polymerase III identity drives robust transcription and expression of snaR-A noncoding RNA
Published in Nature communications (30-05-2022)“…RNA polymerase III (Pol III) includes two alternate isoforms, defined by mutually exclusive incorporation of subunit POLR3G (RPC7α) or POLR3GL (RPC7β), in…”
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Acetyl-Click Screening Platform Identifies Small-Molecule Inhibitors of Histone Acetyltransferase 1 (HAT1)
Published in Journal of medicinal chemistry (27-04-2023)“…HAT1 is a central regulator of chromatin synthesis that acetylates nascent histone H4. To ascertain whether targeting HAT1 is a viable anticancer treatment…”
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Enterotoxigenic Escherichia coli infection and intestinal thiamin uptake: studies with intestinal epithelial Caco-2 monolayers
Published in American Journal of Physiology: Cell Physiology (01-12-2013)“…Infections with enteric pathogens like enterotoxigenic Escherichia coli (ETEC) is a major health issue worldwide and while diarrhea is the major problem,…”
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