Search Results - "Chou, Robert Y.‐T."

Conformational Difference in Human IgG2 Disulfide Isoforms Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry by Zhang, Aming, Fang, Jing, Chou, Robert Y.-T, Bondarenko, Pavel V, Zhang, Zhongqi

“…Both recombinant and natural human IgG2 antibodies have several different disulfide bond isoforms, which possess different global structures, thermal…”
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Field flow fractionation for assessing neonatal Fc receptor and Fcγ receptor binding to monoclonal antibodies in solution by Pollastrini, Joey, Dillon, Thomas M., Bondarenko, Pavel, Chou, Robert Y.-T.

“…Analysis of the strength and stoichiometry of immunoglobulin G (IgG) binding to neonatal Fc receptor (FcRn) and Fcγ receptor (FcγR) is important for evaluating…”
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Impact of antibody subclass and disulfide isoform differences on the biological activity of CD200R and βklotho agonist antibodies by Grujic, Ognjen, Stevens, Jennitte, Chou, Robert Y.-T., Weiszmann, Jennifer V., Sekirov, Laura, Thomson, Christy, Badh, Anita, Grauer, Stephanie, Chan, Brian, Graham, Kevin, Manchulenko, Kathy, Dillon, Thomas M., Li, Yang, Foltz, Ian N.

“…Agonism of cell surface receptors by monoclonal antibodies is dependent not only on its ability to bind the target, but also to deliver a biological signal…”
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Protected hinge in the immunoglobulin G2‐A2 disulfide isoform by Liu, Yaoqing Diana, Chou, Robert Y.‐T., Dillon, Thomas M., Poppe, Leszek, Spahr, Chris, Shi, Stone D. H., Flynn, Gregory C.

“…Human IgG2 consists of disulfide‐mediated structural isoforms, classified by the number of Fab arms disulfide‐linked to the heavy chain hinge. In the IgG2‐B…”
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Protected hinge in the immunoglobulin G2-A sub(2) disulfide isoform by Liu, Yaoqing Diana, Chou, Robert Y-T, Dillon, Thomas M, Poppe, Leszek, Spahr, Chris, Shi, Stone DH, Flynn, Gregory C

“…Human IgG2 consists of disulfide-mediated structural isoforms, classified by the number of Fab arms disulfide-linked to the heavy chain hinge. In the IgG2-B…”
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Protected hinge in the immunoglobulin G2‐A 2 disulfide isoform by Liu, Yaoqing Diana, Chou, Robert Y.‐T., Dillon, Thomas M., Poppe, Leszek, Spahr, Chris, Shi, Stone D. H., Flynn, Gregory C.

“…Abstract Human IgG2 consists of disulfide‐mediated structural isoforms, classified by the number of Fab arms disulfide‐linked to the heavy chain hinge. In the…”
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