Search Results - "Chou, Ming‐Li"
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Intelligent micro-/nanorobots as drug and cell carrier devices for biomedical therapeutic advancement: Promising development opportunities and translational challenges
Published in Biomaterials (01-11-2020)“…Nanotechnology and microfabrication approaches are playing instrumental roles in the development of innovative technologies to fight human diseases. Because of…”
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Human platelet lysates for human cell propagation
Published in Platelets (Edinburgh) (17-02-2021)“…A pathogen-free and standardized xeno-free supplement of growth media is required for the ex vivo propagation of human cells used as advanced therapeutic…”
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Expanding applications of allogeneic platelets, platelet lysates, and platelet extracellular vesicles in cell therapy, regenerative medicine, and targeted drug delivery
Published in Journal of biomedical science (14-09-2023)“…Platelets are small anucleated blood cells primarily known for their vital hemostatic role. Allogeneic platelet concentrates (PCs) collected from healthy…”
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Antimicrobial activity of platelet (PLT)-poor plasma, PLT-rich plasma, PLT gel, and solvent/detergent-treated PLT lysate biomaterials against wound bacteria
Published in Transfusion (Philadelphia, Pa.) (01-01-2013)“…BACKGROUND: Platelet (PLT) gels exhibit antimicrobial activity useful for wound healing. The nature of the antibacterial component(s) is unknown. STUDY DESIGN…”
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Extensive characterization of the composition and functional activities of five preparations of human platelet lysates for dedicated clinical uses
Published in Platelets (Edinburgh) (17-02-2021)“…Human platelet lysates (HPLs), rich in various growth factors and cell growth-promoting molecules, encompass a new range of blood products that are being used…”
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6
Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate
Published in PloS one (19-06-2014)“…Clinical-grade ex vivo expansion of corneal endothelial cells can increase the availability of corneal tissues for transplantation and treatment of corneal…”
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Nanofiltration to remove microparticles and decrease the thrombogenicity of plasma: in vitro feasibility assessment
Published in Transfusion (Philadelphia, Pa.) (01-10-2015)“…BACKGROUND As plasma contains procoagulant microparticles (MPs), removing MPs by 75‐nm nanofiltration may decrease plasma in vitro thrombogenicity while…”
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Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson's disease models
Published in Journal of biomedical science (05-09-2024)“…The burgeoning field of regenerative medicine has significantly advanced with recent findings on biotherapies using human platelet lysates (HPLs), derived from…”
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The protective effect of human platelet lysate in models of neurodegenerative disease: involvement of the Akt and MEK pathways
Published in Journal of tissue engineering and regenerative medicine (01-11-2017)“…Neurodegenerative diseases have huge economic and societal impacts, and place an immense emotional burden on patients and caregivers. Given that platelets have…”
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The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates
Published in Journal of biomedical science (31-10-2019)“…Effective neurorestorative therapies of neurodegenerative diseases must be developed. There is increasing interest in using human platelet lysates, rich in…”
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Neuroprotective activity of a virus‐safe nanofiltered human platelet lysate depleted of extracellular vesicles in Parkinson's disease and traumatic brain injury models
Published in Bioengineering & translational medicine (01-01-2023)“…Brain administration of human platelet lysates (HPL) is a potential emerging biotherapy of neurodegenerative and traumatic diseases of the central nervous…”
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Permissible viewing times of educational projector and TV
Published in Heliyon (01-05-2023)“…Projectors have become one major medium in modern teaching, with large area-size displays emerging as an alternative. What concerns the general public is…”
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TnBP⁄Triton X-45 treatment of plasma for transfusion efficiently inactivates hepatitis C virus
Published in PloS one (06-02-2015)“…Risk of transmission of hepatitis C virus (HCV) by clinical plasma remains high in countries with a high prevalence of hepatitis C, justifying the…”
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Platelet microparticles: Detection and assessment of their paradoxical functional roles in disease and regenerative medicine
Published in Blood reviews (01-07-2014)“…Abstract There is increasing research on and clinical interest in the physiological role played by platelet microparticles (PMPs). PMPs are 0.1–1-μm fragments…”
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Fluconazole induces rapid high-frequency MTL homozygosis with microbiological polymorphism in Candida albicans
Published in Journal of microbiology, immunology and infection (01-12-2017)“…Abstract Background Candida albicans , a common fungal pathogen that can cause opportunistic infections, is regarded as an apparently asexual, diploid fungus…”
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An overview of the role of microparticles/microvesicles in blood components: Are they clinically beneficial or harmful?
Published in Transfusion and apheresis science (01-10-2015)“…Abstract Blood cells and tissues generate heterogeneous populations of cell-derived vesicles, ranging from approximately 50 nm to 1 µm in diameter. Under…”
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Blood-brain crosstalk: the roles of neutrophils, platelets, and neutrophil extracellular traps in neuropathologies
Published in Trends in neurosciences (Regular ed.) (01-09-2023)“…Many neurological diseases involve coagulopathy, inflammation, and neurovascular dysfunction, contributing to blood component-mediated neuroinflammation and…”
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Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment
Published in Brain (London, England : 1878) (29-11-2021)“…Traumatic brain injury (TBI) leads to major brain anatomopathological damages underlined by neuroinflammation, oxidative stress and progressive…”
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Tailor-made purified human platelet lysate concentrated in neurotrophins for treatment of Parkinson's disease
Published in Biomaterials (01-10-2017)“…Human platelet lysates (PLs), which contain multiple neurotrophins, have been proposed for treating neurodegenerative disorders, including Parkinson's disease…”
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The role of microparticles in inflammation and transfusion: A concise review
Published in Transfusion and apheresis science (01-10-2015)“…Abstract Microparticles are small membrane-bound vesicles found in body fluids including peripheral blood. Microparticles are an intrinsic part of blood labile…”
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