Search Results - "Chou, Ai Mei"
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The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia
Published in Journal of cell science (15-07-2016)“…Rif induces dorsal filopodia but the signaling pathway responsible for this has not been identified. We show here that Rif interacts with the I-BAR family…”
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The Toca-1-N-WASP Complex Links Filopodial Formation to Endocytosis
Published in The Journal of biological chemistry (24-04-2009)“…The transducer of Cdc42-dependent actin assembly (Toca-1)-N-WASP complex was isolated as an essential cofactor for Cdc42-driven actin polymerization in vitro…”
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Cdc42 interaction with N-WASP and Toca-1 regulates membrane tubulation, vesicle formation and vesicle motility: implications for endocytosis
Published in PloS one (13-08-2010)“…Transducer of Cdc42-dependent actin assembly (Toca-1) consists of an F-BAR domain, a Cdc42 binding site and an SH3 domain. Toca-1 interacts with N-WASP, an…”
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mDia1 and WAVE2 Proteins Interact Directly with IRSp53 in Filopodia and Are Involved in Filopodium Formation
Published in The Journal of biological chemistry (10-02-2012)“…Filopodia are dynamic actin-rich cell surface protrusions involved in cell migration, axon guidance, and wound healing. The RhoGTPase Cdc42 generates filopodia…”
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Dynamin1 Is a Novel Target for IRSp53 Protein and Works with Mammalian Enabled (Mena) Protein and Eps8 to Regulate Filopodial Dynamics
Published in The Journal of biological chemistry (29-08-2014)“…Filopodia are dynamic actin-based structures that play roles in processes such as cell migration, wound healing, and axonal guidance. Cdc42 induces filopodial…”
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Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development
Published in Scientific reports (09-01-2017)“…The insulin receptor substrate of 53 kDa, IRSp53, is an adaptor protein that works with activated GTPases, Cdc42 and Rac, to modulate actin dynamics and…”
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The Toca-1-N-WASP Complex Links Filopodial Formation to EndocytosisS
Published in The Journal of biological chemistry (24-04-2009)“…The t ransducer o f C dc42-dependent a ctin assembly (Toca-1)-N-WASP complex was isolated as an essential cofactor for Cdc42-driven actin polymerization in…”
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Tissue engineering of a periodontal ligament-alveolar bone graft construct
Published in The International journal of oral and maxillofacial implants (01-07-2006)“…This paper reports on a 2-phase study of a novel membrane-scaffold graft construct, its ability to support periodontal ligament fibroblast (PDLF) and alveolar…”
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