Search Results - "Chotani, M A"

Redox Regulation of Vascular Smooth Muscle Cell Differentiation by Su, B, Mitra, S, Gregg, H, Flavahan, S, Chotani, M A, Clark, K R, Goldschmidt-Clermont, P J, Flavahan, N A

“…ABSTRACT—Experiments were performed to determine the role of reactive oxygen species (ROS) in regulating vascular smooth muscle cell (VSMC) phenotype. After…”
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Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries by Chotani, M A, Flavahan, S, Mitra, S, Daunt, D, Flavahan, N A

“…Cold constricts cutaneous blood vessels by increasing the reactivity of smooth muscle alpha(2)-adrenergic receptors (alpha(2)-ARs). Experiments were performed…”
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Regulation of a promoter of the fibroblast growth factor 1 gene in prostate and breast cancer cells by Payson, Robert A, Chotani, Maqsood A, Chiu, Ing-Ming

“…FGF-1 mRNA is expressed in the prostate cancer cell lines LNCaP and PC-3 and in the breast carcinoma cell line MDA-MB-231. Levels of FGF-1 mRNA have been shown…”
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Gene structure and differential expression of acidic fibroblast growth factor mRNA: identification and distribution of four different transcripts by Myers, R L, Payson, R A, Chotani, M A, Deaven, L L, Chiu, I M

“…We have isolated four cDNA clones coding for human acidic fibroblast growth factor (aFGF) containing alternative 5' untranslated exons. Using RNAase protection…”
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Cloning of two novel forms of human acidic fibroblast growth factor (aFGF) mRNA by Payson, Robert A., Canatan, Halit, Chotani, Maqsood A., Wang, Wen-Pin, Harris, Stephen E., Myers, René L., Chiu, Ing-Ming

“…We have previously isolated two different aFGF cDNA clones from kidney and brain. The two corresponding mRNA, designated aFGF 1.A and 1.B, are the predominant…”
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The Small GTPases Ras, Rac, and Cdc42 Transcriptionally Regulate Expression of Human Fibroblast Growth Factor 1 by Chotani, Maqsood A., Touhalisky, Kathy, Chiu, Ing-Ming

“…Four distinct promoters (1A, 1B, 1C, and 1D) of fibroblast growth factor 1 (FGF1), spaced up to 70 kilobase pairs apart, direct the expression of alternatively…”
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Differential regulation of human fibroblast growth factor 1 transcripts provides a distinct mechanism of cell-specific growth factor expression by CHOTANI, M. A, CHIU, I.-M

“…Four variants of fibroblast growth factor 1 (FGF-1) mRNA, FGF-1.A, -1.B, -1.C, and -1.D, originate from four discrete promoters of the gene. Each promoter is…”
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Functional Characterization of the Brain-specific FGF-1 Promoter, FGF-1.B (∗) by Myers, René L., Ray, Subir K., Eldridge, Rebecca, Chotani, Maqsood A., Chiu, Ing-Ming

“…Expression of alternatively spliced human FGF-1 (or aFGF) transcripts is regulated in a tissue-specific manner via multiple promoters. To identify the…”
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Human fibroblast growth factor 1 gene expression in vascular smooth muscle cells is modulated via an alternate promoter in response to serum and phorbol ester by Chotani, Maqsood A., Payson, Robert A., Winkles, Jeffrey A., Chiu, Ing-Ming

“…We have previously isolated the human FGF-1 gene in order to elucidate the molecular basis of its gene expression. The gene spans over 100 kbp and encodes…”
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Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors by Eid, A H, Chotani, M A, Mitra, S, Miller, T J, Flavahan, N A

“…Cold increases cutaneous vasoconstriction by unmasking the contractile activity of alpha(2C)-adrenoceptors (alpha(2C)-ARs) in vascular smooth muscle cells…”
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Estrogen increases smooth muscle expression of alpha2C-adrenoceptors and cold-induced constriction of cutaneous arteries by Eid, A H, Maiti, K, Mitra, S, Chotani, M A, Flavahan, S, Bailey, S R, Thompson-Torgerson, C S, Flavahan, N A

“…Raynaud's phenomenon, which is characterized by intense cold-induced constriction of cutaneous arteries, is more common in women compared with men…”
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The vasculopathy of Raynaud's phenomenon and scleroderma by Flavahan, Nicholas A, Flavahan, Sheila, Mitra, Srabani, Chotani, Maqsood A

“…The scleroderma (SSc) disease process involves dramatic dysfunction in acute and chronic vascular regulatory mechanisms; it presents initially with heightened…”
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Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells by Chotani, Maqsood A, Mitra, Srabani, Su, Baogen Y, Flavahan, Sheila, Eid, Ali H, Clark, K Reed, Montague, Christine R, Paris, Herve, Handy, Diane E, Flavahan, Nicholas A

“…This study analyzed the regulation of alpha2-adrenoceptors (alpha2-ARs) in human vascular smooth muscle cells (VSMs). Saphenous veins and dermal arterioles or…”
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Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells by Jeyaraj, Selvi C, Unger, Nicholas T, Eid, Ali H, Mitra, Srabani, Paul El-Dahdah, N, Quilliam, Lawrence A, Flavahan, Nicholas A, Chotani, Maqsood A

“…Intracellular signaling by the second messenger cyclic AMP (cAMP) activates the Ras-related small GTPase Rap1 through the guanine exchange factor Epac. This…”
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Cooling evokes redistribution of alpha2C-adrenoceptors from Golgi to plasma membrane in transfected human embryonic kidney 293 cells by Jeyaraj, S C, Chotani, M A, Mitra, S, Gregg, H E, Flavahan, N A, Morrison, K J

“…Cold-induced vasoconstriction in cutaneous blood vessels is mediated by increased constrictor activity of vascular alpha2-adrenoceptors (alpha2-ARs). In mouse…”
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A recombinant PCR approach requiring only three non-chimeric primers to generate a minigene of interest by Chotani, M A, Chiu, I M

“…The recombinant PCR allows construction of chimeric molecules. Here we describe this approach utilizing non-chimeric primers. Unlike previous recombinant PCR…”
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Intracellular membranes are more fluid in platelets of Alzheimer's disease patients by Piletz, J E, Sarasua, M, Whitehouse, P, Chotani, M

“…We studied 12 patients with probable Alzheimer's disease versus age- and sex-matched healthy control subjects. Platelets were subfractionated into…”
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