Search Results - "Choshi, Phuti"
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Dose Dependent Antimicrobial Cellular Cytotoxicity-Implications for ex vivo Diagnostics
Published in Frontiers in pharmacology (10-08-2021)“…and diagnostics, such as interferon-γ (IFN-γ) release enzyme linked ImmunoSpot (ELISpot) and flow cytometry, are increasingly employed in the research and…”
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Skin infiltrating T-cell profile of drug reaction with eosinophilia and systemic symptoms (DRESS) reactions among HIV-infected patients
Published in Frontiers in medicine (05-05-2023)“…Drug Reaction with Eosinophilia Systemic Symptoms (DRESS) is more common in persons living with HIV (PLHIV), and first-line anti-TB drugs (FLTDs) and…”
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Corrigendum: Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics
Published in Frontiers in pharmacology (02-09-2021)Get full text
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Clinical profiles and HLA haplotypes in patients with severe cutaneous adverse reactions in Lusaka, Zambia
Published in International journal of dermatology (30-07-2024)Get full text
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Drug hypersensitivity in HIV infection
Published in Current opinion in allergy and clinical immunology (01-08-2019)“…PURPOSE OF REVIEWImmune-mediated adverse drug reactions (IM-ADRs) are many times more common in HIV-infected patients. Usual offending drugs include…”
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HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity
Published in Journal of investigative dermatology (01-03-2023)“…Skin diseases are hallmarks of progressive HIV-related immunosuppression, with severe noninfectious inflammatory and hypersensitivity conditions as common as…”
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IFN-γ ELISpot in Severe Cutaneous Adverse Reactions to First-Line Antituberculosis Drugs in an HIV Endemic Setting
Published in Journal of investigative dermatology (01-11-2022)“…Severe cutaneous adverse reactions related to first-line antituberculosis drugs are associated with high mortality and long-term morbidity. Oral sequential…”
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Dose Dependent Antimicrobial Cellular Cytotoxicity – Implications for ex vivo diagnostics
Published in Journal of allergy and clinical immunology (01-02-2021)Get full text
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Single-cell multi-omic approaches define common molecular and cellular signals of dominant antigen-driven cells at the site of drug-induced Stevens Johnson Syndrome and Toxic Epidermal Necrolysis (SJS/TEN) tissue damage
Published in Journal of allergy and clinical immunology (01-02-2022)Get full text
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First-Line Antituberculosis Drug Challenge Reactions in Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome in an HIV Endemic Setting
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-10-2024)“…In high HIV prevalence settings, first-line antituberculosis drug (FLTD)-associated drug reaction with eosinophilia and systemic symptoms (DRESS) poses…”
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Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis
Published in Nature communications (08-10-2024)“…Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen…”
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