Search Results - "Choromańska, Anna"
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Extracellular Vesicles as Drug Transporters
Published in International journal of molecular sciences (01-06-2023)“…Extracellular vesicles (EVs) are lipid bilayer-delimited particles. According to their size and synthesis pathway, EVs can be classified into exosomes,…”
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Exosomes and Other Extracellular Vesicles with High Therapeutic Potential: Their Applications in Oncology, Neurology, and Dermatology
Published in Molecules (Basel, Switzerland) (15-02-2022)“…Until thirty years ago, it was believed that extracellular vesicles (EVs) were used to remove unnecessary compounds from the cell. Today, we know about their…”
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Electroporation and Electrochemotherapy in Gynecological and Breast Cancer Treatment
Published in Molecules (Basel, Switzerland) (12-04-2022)“…Gynecological carcinomas affect an increasing number of women and are associated with poor prognosis. The gold standard treatment plan is mainly based on…”
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Comparative Analysis of Exosomes and Extracellular Microvesicles in Healing Pathways: Insights for Advancing Regenerative Therapies
Published in Molecules (Basel, Switzerland) (01-08-2024)“…Exosomes and microvesicles bear great potential to broaden therapeutic options in the clinical context. They differ in genesis, size, cargo, and composition…”
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Evaluation of Wound Healing Activity of Salvianolic Acid B on In Vitro Experimental Model
Published in International journal of molecular sciences (20-07-2021)“…Despite a wide range of bactericides and antiseptics, the treatment of chronic or complicated wounds is still a major challenge for modern medicine. Topical…”
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Factors Determining Epithelial-Mesenchymal Transition in Cancer Progression
Published in International journal of molecular sciences (17-08-2024)“…Epithelial-mesenchymal transition (EMT) is a process in which an epithelial cell undergoes multiple modifications, acquiring both morphological and functional…”
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Utilizing Extracellular Vesicles for Eliminating 'Unwanted Molecules': Harnessing Nature's Structures in Modern Therapeutic Strategies
Published in Molecules (Basel, Switzerland) (21-02-2024)“…Extracellular vesicles (EVs) are small phospholipid bilayer-bond structures released by diverse cell types into the extracellular environment, maintaining…”
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Investigation into the Neuroprotective and Therapeutic Potential of Plant-Derived Chk2 Inhibitors
Published in International journal of molecular sciences (15-07-2024)“…Nature provides us with a rich source of compounds with a wide range of applications, including the creation of innovative drugs. Despite advancements in…”
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9
Electroporation-derived melanoma extracellular particles activate fibroblasts
Published in Biochimica et biophysica acta. General subjects (01-12-2024)“…Although the pulse electric field (PEF) has been used in electrochemotherapy (ECT) for many years, the kinetics and profile of extracellular particles (EPs)…”
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10
Nanosecond PEF Induces Oxidative Stress and Apoptosis via Proteasomal Activity Inhibition in Gastric Adenocarcinoma Cells with Drug Resistance
Published in International journal of molecular sciences (01-11-2022)“…Nanosecond (ns) pulsed electric field (PEF) is a technology in which the application of ultra-short electrical pulses can be used to disrupt the barrier…”
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11
Modifications of Plasma Membrane Organization in Cancer Cells for Targeted Therapy
Published in Molecules (Basel, Switzerland) (25-03-2021)“…Modifications of the composition or organization of the cancer cell membrane seem to be a promising targeted therapy. This approach can significantly enhance…”
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Preparation and characterization of new zinc(II) phthalocyanine — Containing poly(l-lactide)-b-poly(ethylene glycol) copolymer micelles for photodynamic therapy
Published in Journal of photochemistry and photobiology. B, Biology (01-07-2016)“…Poly(l-lactide)-b-poly(ethylene oxide) block copolymer (mPEG-b-PLLA) micelles were fabricated and applied as a new biodegradable and biocompatible nanocarrier…”
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13
Telomerase Inhibition in the Treatment of Leukemia: A Comprehensive Review
Published in Antioxidants (01-04-2024)“…Leukemia, characterized by the uncontrolled proliferation and differentiation blockage of myeloid or lymphoid precursor cells, presents significant therapeutic…”
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Oral Wound Healing Potential of Polygoni Cuspidati Rhizoma et Radix Decoction-In Vitro Study
Published in Pharmaceuticals (Basel, Switzerland) (10-02-2023)“…( rhizomes of Houtt.) is a pharmacopoeial raw material in Europe and China. In traditional medicine, one of the applications for rhizomes is wound healing. In…”
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Evaluation of the Anticancer Activity of Calcium Ions Introduced into Human Breast Adenocarcinoma Cells MCF-7/WT and MCF-7/DOX by Electroporation
Published in Pharmaceuticals (Basel, Switzerland) (30-05-2023)“…Breast cancer ranks among the top three most common malignant neoplasms in Poland. The use of calcium ion-assisted electroporation is an alternative approach…”
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Chemical Composition of East Asian Invasive Knotweeds, their Cytotoxicity and Antimicrobial Efficacy Against Cariogenic Pathogens: An In-Vitro Study
Published in Medical science monitor (04-05-2019)“…BACKGROUND Giant knotweeds originating from East Asia, such as Reynoutria japonica, and Reynoutria sachalinensis, and their hybrid such as Reynoutria x…”
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In Vitro Gingival Wound Healing Activity of Extracts from Reynoutria japonica Houtt Rhizomes
Published in Pharmaceutics (22-10-2021)“…Rhizomes of Reynoutria japonica Houtt. are a traditional Chinese medicinal herb (Polygoni cuspidati rhizoma, hu zhang) used for treatment of numerous diseases…”
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Electrochemotherapy with Calcium Chloride and 17β-Estradiol Modulated Viability and Apoptosis Pathway in Human Ovarian Cancer
Published in Pharmaceutics (24-12-2020)“…Estrogens (Es) play a significant role in the carcinogenesis and progression of ovarian malignancies. Depending on the concentration, Es may have a protective…”
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Cytotoxic Effect of Vanicosides A and B from Reynoutria sachalinensis Against Melanotic and Amelanotic Melanoma Cell Lines and in silico Evaluation for Inhibition of BRAFV600E and MEK1
Published in International journal of molecular sciences (29-06-2020)“…Vanicosides A and B are the esters of hydroxycinnamic acids with sucrose, occurring in a few plant species from the Polygonaceae family. So far, vanicosides A…”
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Overcoming Antigen Escape and T-Cell Exhaustion in CAR-T Therapy for Leukemia
Published in Cells (Basel, Switzerland) (23-09-2024)“…Leukemia is a prevalent pediatric cancer with significant challenges, particularly in relapsed or refractory cases. Chimeric antigen receptor T-cell (CAR-T)…”
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