Search Results - "Chorawala, Mehul R"

The future of cancer immunotherapy: DNA vaccines leading the way by Pandya, Aanshi, Shah, Yesha, Kothari, Nirjari, Postwala, Humzah, Shah, Aayushi, Parekh, Priyajeet, Chorawala, Mehul R.

“…Immuno-oncology has revolutionized cancer treatment and has opened up new opportunities for developing vaccination methods. DNA-based cancer vaccines have…”
Get full text

Integrated blood and organ profile analysis to evaluate ameliorative effects of kaempferol on 5-fluorouracil-induced toxicity by Sharma, Abhilasha, Chorawala, Mehul R., Rawal, Rakesh M., Shrivastava, Neeta

“…Colorectal cancer (CRC) treatment strategies encompass a triad of medical interventions: surgery, radiotherapy, and chemotherapy. Among these, the use of…”
Get full text

Harnessing three-dimensional (3D) cell culture models for pulmonary infections: State of the art and future directions by Shah, Disha D., Raghani, Neha R., Chorawala, Mehul R., Singh, Sudarshan, Prajapati, Bhupendra G.

“…Pulmonary infections have been a leading etiology of morbidity and mortality worldwide. Upper and lower respiratory tract infections have multifactorial…”
Get full text

Reprogramming of Lipid Metabolism in Cancer: New Insight into Pathogenesis and Therapeutic Strategies by Saikia, Surovi, Ahmed, Firdush, Prajapati, Bhupendra G, Padma, V Vijaya, Chorawala, Mehul R, Postwala, Humzah I, Bhattacharya, Sankha

“…Lipids have received less attention than nucleic acids and proteins, which play a major role in building up the cell. They are a complex group of biomolecules…”
Get more information

ADAMTS13 Retards Progression of Diabetic Nephropathy by Inhibiting Intrarenal Thrombosis in Mice by Dhanesha, Nirav, Doddapattar, Prakash, Chorawala, Mehul R, Nayak, Manasa K, Kokame, Koichi, Staber, Janice M, Lentz, Steven R, Chauhan, Anil K

“…OBJECTIVE—ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type I repeats-13) prevents microvascular thrombosis by cleaving prothrombogenic…”
Get full text

Harnessing Cannabis sativa Oil for Enhanced Skin Wound Healing: The Role of Reactive Oxygen Species Regulation by Israni, Dipa K, Raghani, Neha R, Soni, Jhanvi, Shah, Mansi, Prajapati, Bhupendra G, Chorawala, Mehul R, Mangmool, Supachoke, Singh, Sudarshan, Chittasupho, Chuda

“…emerges as a noteworthy candidate for its medicinal potential, particularly in wound healing. This review article explores the efficacy of cannabis oil in…”
Get full text

Revamping the innate or innate-like immune cell-based therapy for hepatocellular carcinoma: new mechanistic insights and advanced opportunities by Shah, Disha D., Dave, Bhavarth P., Patel, Parv A., Chorawala, Mehul R., Patel, Vishvas N., Shah, Palak A., Patel, Manish P.

“…A cancerous tumour termed hepatocellular carcinoma (HCC) is characterized by inflammation and subsequently followed by end-stage liver disease and necrosis of…”
Get full text

An Insight on Microfluidic Organ-on-a-Chip Models for PM2.5-Induced Pulmonary Complications by Shah, Disha, Dave, Bhavarth, Chorawala, Mehul R., Prajapati, Bhupendra G., Singh, Sudarshan, M. Elossaily, Gehan, Ansari, Mohd Nazam, Ali, Nemat

“…Pulmonary diseases like asthma, chronic obstructive pulmonary disorder, lung fibrosis, and lung cancer pose a significant burden to global human health. Many…”
Get full text

Assessment of potential drug–drug interactions among outpatients in a tertiary care hospital: focusing on the role of P-glycoprotein and CYP3A4 (retrospective observational study) by Patel, Krupa A., Bhatt, Masumi H., Hirani, Rajvi V., Patel, Vidheesha A., Patel, Vishvas N., Shah, Gaurang B., Chorawala, Mehul R.

“…Selecting a medicine has a significant impact on the quality of therapy including efficacy and safety. P-glycoprotein and CYP3A4 share several common…”
Get full text

A systemic review and meta-analysis of Aflibercept plus FOLFIRI regimen as a second-line treatment for metastatic colorectal cancer: A PRISMA compliant pooled analysis of randomized controlled trials and single arm studies to assess efficacy and safety by Thakur, Anshu, Chorawala, Mehul R., Patel, Roshni S.

“…Aflibercept; a decoy receptor for vascular endothelial growth factors (VEGFs) and placental growth factor (PLGF), in combination with FOLFIRI (leucovorin…”
Get full text

Smooth muscle cell-specific fibronectin-EDA mediates phenotypic switching and neointimal hyperplasia by Jain, Manish, Dhanesha, Nirav, Doddapattar, Prakash, Chorawala, Mehul R, Nayak, Manasa K, Cornelissen, Anne, Guo, Liang, Finn, Aloke V, Lentz, Steven R, Chauhan, Anil K

“…Fibronectin-splice variant containing extra domain A (Fn-EDA) is associated with smooth muscle cells (SMCs) following vascular injury. The role of SMC-derived…”
Get full text

Unveiling the genetic and epigenetic landscape of colorectal cancer: new insights into pathogenic pathways by Postwala, Humzah, Shah, Yesha, Parekh, Priyajeet S., Chorawala, Mehul R.

“…Colorectal cancer (CRC) is a complex disease characterized by genetic and epigenetic alterations, playing a crucial role in its development and progression…”
Get full text

Establishing the applicability of cancer vaccines in combination with chemotherapeutic entities: current aspect and achievable prospects by Kothari, Nirjari, Postwala, Humzah, Pandya, Aanshi, Shah, Aayushi, Shah, Yesha, Chorawala, Mehul R.

“…Cancer immunotherapy is one of the recently developed cancer treatment modalities. When compared with conventional anticancer drug regimens, immunotherapy has…”
Get full text

Fn-EDA (Fibronectin Containing Extra Domain A) in the Plasma, but Not Endothelial Cells, Exacerbates Stroke Outcome by Promoting Thrombo-Inflammation by Dhanesha, Nirav, Chorawala, Mehul R, Jain, Manish, Bhalla, Abhinav, Thedens, Daniel, Nayak, Manasa, Doddapattar, Prakash, Chauhan, Anil K

“…BACKGROUND AND PURPOSE—Cellular Fn-EDA (fibronectin containing extra domain A) is expressed in activated endothelial cells and elevated in circulation in…”
Get full text

Molnupiravir: an antiviral drug against COVID-19 by Dave, Bhavarth, Shah, Kashvi C., Chorawala, Mehul R., Shah, Nirav, Patel, Pranjal, Patel, Suzan, Shah, Palak

“…SARS-CoV-2, the virus responsible for COVID-19, has caused numerous deaths worldwide and poses significant challenges. Researchers have recently studied a new…”
Get full text

Navigating the landscape of theranostics in nuclear medicine: current practice and future prospects by Shah, Aayushi, Dabhade, Akshada, Bharadia, Hetvi, Parekh, Priyajeet S., Yadav, Mayur R., Chorawala, Mehul R.

“…Theranostics refers to the combination of diagnostic biomarkers with therapeutic agents that share a specific target expressed by diseased cells and tissues…”
Get full text

Deletion of Extra Domain A of Fibronectin Reduces Acute Myocardial Ischaemia/Reperfusion Injury in Hyperlipidaemic Mice by Limiting Thrombo-Inflammation by Chorawala, Mehul R, Prakash, Prem, Doddapattar, Prakash, Jain, Manish, Dhanesha, Nirav, Chauhan, Anil K

“…Fibronectin splicing variant containing extra domain A (Fn-EDA), which is an endogenous ligand for Toll-like receptor 4 (TLR4), is present in negligible…”
Get more information

Biogenic metallic nanoparticles: from green synthesis to clinical translation by Shah, Disha D., Chorawala, Mehul R., Mansuri, Mohammad Kaif A., Parekh, Priyajeet S., Singh, Sudarshan, Prajapati, Bhupendra G.

“…Biogenic metallic nanoparticles (NPs) have garnered significant attention in recent years due to their unique properties and various applications in different…”
Get full text

Endothelial Cell–Derived Von Willebrand Factor, But Not Platelet-Derived, Promotes Atherosclerosis in Apolipoprotein E–Deficient Mice by Doddapattar, Prakash, Dhanesha, Nirav, Chorawala, Mehul R, Tinsman, Chandler, Jain, Manish, Nayak, Manasa K, Staber, Janice M, Chauhan, Anil K

“…OBJECTIVE—VWF (von Willebrand factor) is synthesized by endothelial cells and megakaryocytes and is known to contribute to atherosclerosis. In vitro studies…”
Get full text

Combating relapsed and refractory Mantle cell lymphoma with novel therapeutic armamentarium: Recent advances and clinical prospects by Raghani, Neha R., Shah, Disha D., Shah, Tithi S., Chorawala, Mehul R., Patel, Rakesh B.

“…Mantle cell lymphoma (MCL) is a rare, aggressive subtype of non-Hodgkin’s lymphoma (NHL), accounting for 5% of all cases. Due to its virulence factor, it is an…”
Get full text