Search Results - "Chora, Ângelo Ferreira"
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1
Host lung microbiota promotes malaria-associated acute respiratory distress syndrome
Published in Nature communications (29-06-2022)“…Severe malaria can manifest itself with a variety of well-recognized clinical phenotypes that are highly predictive of death – severe anaemia, coma (cerebral…”
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2
DNA damage independent inhibition of NF-κB transcription by anthracyclines
Published in eLife (07-12-2022)“…© 2022, Chora, Pedroso et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and…”
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3
The reciprocal influence of the liver and blood stages of the malaria parasite's life cycle
Published in International journal for parasitology (01-10-2022)“…While the liver and blood stages of the Plasmodium life cycle are commonly regarded as two separate fields of malaria research, several studies have pointed…”
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4
Microbiota, a Third Player in the Host–Plasmodium Affair
Published in Trends in parasitology (01-01-2020)“…Plasmodium, the causative agent of malaria, is responsible for more than 200 million new infections and 400 000 deaths yearly. While in recent years the…”
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5
Disrupting Plasmodium UIS3–host LC3 interaction with a small molecule causes parasite elimination from host cells
Published in Communications biology (19-11-2020)“…© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis
Published in Immunity (Cambridge, Mass.) (14-03-2023)“…Plasmodium replicates within the liver prior to reaching the bloodstream and infecting red blood cells. Because clinical manifestations of malaria only arise…”
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7
A spatiotemporally resolved single-cell atlas of the Plasmodium liver stage
Published in Nature (London) (17-11-2022)“…Malaria infection involves an obligatory, yet clinically silent liver stage 1 , 2 . Hepatocytes operate in repeating units termed lobules, exhibiting…”
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8
Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection
Published in Nature medicine (01-01-2014)“…After mosquito bite, the malaria parasite first infects the liver, where it is thought to be undetected by the host immune system as it develops into the…”
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9
Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis
Published in Immunity (Cambridge, Mass.) (14-11-2013)“…Severe sepsis remains a poorly understood systemic inflammatory condition with high mortality rates and limited therapeutic options in addition to organ…”
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10
Elimination of Hepatic Rodent Plasmodium Parasites by Amino Acid Supplementation
Published in iScience (18-12-2020)“…Plasmodium parasites, causative agents of malaria, scavenge host nutrients to sustain their intracellular replication. Modulation of the host's nutritional…”
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11
RNAi screen for kinases and phosphatases that play a role in antigen presentation by dendritic cells
Published in European journal of immunology (01-07-2012)“…© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Effective CD8(+) T-cell responses against tumor or microbial antigens that are not directly expressed in…”
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12
Role of the Protective Gene Heme Oxygenase-1 in the Control of T Cell Mediated Responses
Published 01-01-2008“…As reacções inflamatórias, geralmente desencadeadas por infeccões e/ou lesões a nível dos tecidos, desempenham um papel fundamental na iniciação de respostas…”
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