Search Results - "Chopra, Bhawna"
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Inflammation as a Therapeutic Target for Various Deadly Disorders: A Review
Published in Current drug targets (01-01-2020)“…Inflammation is the multifaceted biological response of vascular tissues against injurious stimuli such as pathogens, irritants or infection. However, when…”
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2
Emerging Role of Terpenoids for the Treatment of Cancer: A Review
Published in Mini reviews in medicinal chemistry (01-01-2021)“…Terpenes are natural compounds found in several organisms belonging to the animal and plant kingdom, therefore, constitute the largest class of natural…”
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3
A Review of Clinical Studies Assessing the Therapeutic Efficacy of Escitalopram: A Step Towards Development
Published in CNS & neurological disorders drug targets (2023)“…Major depression is a debilitating, sometimes fatal disorder, deteriorating the quality of life and well-being. Escitalopram showed highly selective and…”
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4
A Review on Novel Applications of Nanotechnology in the Management of Prostate Cancer
Published in Current drug delivery (01-01-2024)“…Prostate cancer continues to be a serious danger to men's health, despite advances in the field of cancer nanotechnology. Although different types of cancer…”
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5
Bakuchiol: A Potential Anticancer Compound from Psoralea corylifolia Linn
Published in Anti-cancer agents in medicinal chemistry (01-01-2023)“…Bakuchiol is a monoterpene phenol isolated from the seeds of Psoralea corylifolia Linn. It is used traditionally in Indian and Chinese medicine and has been…”
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Pulegone: An Emerging Oxygenated Cyclic Monoterpene Ketone Scaffold Delineating Synthesis, Chemical Reactivity, and Biological potential
Published in Recent advances in anti-infective drug discovery (2023)“…Pulegone ((R)-5-Methyl-2-(1-methylethylidine) cyclohexanone) is a pharmacologically active, natural monoterpene ketone obtained from leaves and flowering tops…”
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7
Hesperidin: A Potential Therapeutic Agent against COVID-19
Published in Current drug discovery technologies (01-03-2023)“…COVID-19, aka Coronavirus Disease 2019, triggered by new severe acute respiratory syndrome coronavirus-2 or SARS-CoV-2, is now a public health emergency due to…”
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Pharmacological properties of Chebulinic acid and related ellagitannins from nature: An emerging contemporary bioactive entity
Published in Pharmacological research. Modern Chinese medicine (01-12-2022)“…Terminalia chebula, (Family: Combretaceae) is a medicinally active plant possess a wide spectrum of biological activities and contain numerous bioactive…”
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Synergistic Effect of Piperine and its Derivatives: A Comprehensive Review
Published in Current drug research reviews (2023)“…Piperine is a fascinating substance since it can be used as a biomarker in combination with other bioactive compounds or their analogues, as well as…”
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10
Psoralea corylifolia L. (Buguchi) — Folklore to modern evidence: Review
Published in Fitoterapia (01-10-2013)“…Psoralea corylifolia is an important medicinal plant which is used in several traditional medicines to cure various diseases. The plant extracts have been…”
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Therapeutic Potential and Clinical Effectiveness of Quercetin: A Dietary Supplement
Published in Recent advances in food, nutrition & agriculture (2024)“…Fruits and vegetables (like apples, citrus, grapes, onions, parsley, etc.) are the primary dietary sources of quercetin. In addition, isolated quercetin is…”
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12
Synthesis, antimicrobial and anti-inflammatory activities of some novel 5-substituted imidazolone analogs
Published in Chinese chemical letters (01-05-2016)“…In view of potent antimicrobial and anti-inflammatory activities exhibited by S-substituted imidazolones, a variety of novel imidazolone analogs 3a-I were…”
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13
Synthesis and In Silico Molecular Docking Studies on Substituted Piperic Acid Derivatives as Inhibitors of Bacterial DNA Gyrase
Published in Current computer-aided drug design (01-01-2020)“…Piperine or piperic acid was isolated from fruits of Piper nigrum and had been reported as pharmacological valuable bioactive constituents. Keeping in view, a…”
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14
Natural products: A lead for drug discovery and development
Published in Phytotherapy research (01-09-2021)“…Natural products are used since ancient times in folklore for the treatment of various ailments. Plant‐derived products have been recognized for many years as…”
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Co-processed excipients: Recent advances and future perspective
Published in Journal of drug delivery science and technology (01-05-2022)“…The demands on the functionality of excipients are increasing day by day because of the emergence of high-speed tableting machines and the use of direct…”
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16
Development and Validation of Robust, Highly Sensitive and Stability-Indicating RP-HPLC Method for Estimation of Deferasirox and its Degradation Products
Published in Journal of chromatographic science (01-10-2024)“…Abstract A rapid, simple and highly sensitive stability-indicating reverse-phase high-performance liquid chromatographic technique, coupled with a photodiode…”
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Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders
Published in Bioorganic chemistry (01-04-2022)“…[Display omitted] •PTP1B is an emerging therapeutic target for various human disorders like T2D, obesity and cancer.•A large number of molecules of broad…”
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Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects
Published in European journal of medicinal chemistry (15-02-2023)“…The pursuit of activating the HDAC inhibitory template towards additional mechanisms spurred us to design dual modulators (Sig-1R agonist - HDAC inhibitor) via…”
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In silico docking based screening of constituents from Persian shallot as modulators of human glucokinase
Published in Journal of diabetes and metabolic disorders (29-12-2022)“…Purpose Small molecule glucokinase (GK) modulators not only decrease fasting and basal plasma sugar contents but also progress glucose tolerance. The…”
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Synthesis and Anti-Inflammatory Activity of Some O-Propargylated-N-acetylpyrazole Derived from 1,3-Diarylpropenones
Published in International Journal of Medicinal Chemistry (Online) (01-01-2016)“…In search of novel effective potent therapeutic agents delivered by oral route for inflammation treatment, some novel O-propargylated-N-acetylpyrazole analogs…”
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