Search Results - "Choppa, Paul"

A novel method for the detection, quantitation, and breakpoint cluster region determination of t(15;17) fusion transcripts using a one-step real-time multiplex RT-PCR by CHOPPA, Paul C, GOMEZ, Jamie, VALL, Horacio G, OWENS, Marilyn, RAPPAPORT, Henry, LOPATEGUI, Jean R

“…Individuals with acute promyelocytic leukemia (APL) usually express 1 of 3 primary hybrid transcripts associated with a t(15;17). The 3 fusion transcripts are…”
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Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors by Hovelson, Daniel H, McDaniel, Andrew S, Cani, Andi K, Johnson, Bryan, Rhodes, Kate, Williams, Paul D, Bandla, Santhoshi, Bien, Geoffrey, Choppa, Paul, Hyland, Fiona, Gottimukkala, Rajesh, Liu, Guoying, Manivannan, Manimozhi, Schageman, Jeoffrey, Ballesteros-Villagrana, Efren, Grasso, Catherine S, Quist, Michael J, Yadati, Venkata, Amin, Anmol, Siddiqui, Javed, Betz, Bryan L, Knudsen, Karen E, Cooney, Kathleen A, Feng, Felix Y, Roh, Michael H, Nelson, Peter S, Liu, Chia-Jen, Beer, David G, Wyngaard, Peter, Chinnaiyan, Arul M, Sadis, Seth, Rhodes, Daniel R, Tomlins, Scott A

“…Abstract Next-generation sequencing (NGS) has enabled genome-wide personalized oncology efforts at centers and companies with the specialty expertise and…”
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Abstract 69: Identification of rare and novel alleles in FFPE tumor samples using laser capture microdissection (LCM) and Ampliseq™ sequencing technologies by Jackson, Stephen, Choppa, Paul, Kulvar, Kulvinda, Schmidt, Kristin

“…Abstract Tumors are becoming recognized as genetically heterogeneous masses of cells with different clonal histories. Identifying the mutations present in…”
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Abstract 3420: Integrative tumor profiling beyond panel sequencing by Lau, Corine K., Harley, Alena S., Choppa, Paul, Cooc, Janine, Kyshtoobayeva, Ainura, Jun, Natalia, Dayrit, Mark, Delport, Wayne, Saldivar, Mark, Jun, Yop, Trivedi, Raaj, Gylfe, Alexandra E., Lacey, Travis R., Cohen, Ezra, Bloom, Kenneth, Shinbrot, Eve

“…Abstract Introduction: Targeted cancer therapies rely on the identification of biomarkers specific to the tumors. Next generation sequencing (NGS) based…”
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Oncomine Knowledgebase Reporter: An information management system to link published evidence with cancer gene variants detected by multivariate tests by Bandla, Santhoshi, Galimberti, David, Kopp, Kenneth, Anstead, Sarah, Zurenko, Christopher, Bonevich, Nikki, Cyanam, Dinesh, Faershtein, Jane, Chi, David, Choppa, Paul, McIntyre, Jody, Hogan, Michael, Sadis, Seth

“…Abstract only…”
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Tumor profiling from whole-genome and whole transcriptome sequencing to uncover gene fusions and structural variations in clinically relevant cancer genes by Gylfe, Alexandra E, Shinbrot, Eve, Kakaradov, Boyko, Delport, Wayne, Lau, Corine K, Krishnan, Subha, Perlina, Ally, Natarajan, Thanemozhi G, Sainger, Rachana, Pelak, Kimberly, Choppa, Paul, Cooc, Janine, Biggs, William, Smith, Heather L, Perkins, Brad, Jones, Daniel G, Nehring, Ramlah B, Cohen, Ezra E.W., Bloom, Kenneth Joel

“…Abstract only e23118 Background: Current targeted cancer therapies rely on the identification of clinically relevant somatic alterations in the tumor. Hotspot…”
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Sensitive multiplex detection of KRAS codons 12 and 13 mutations in paraffin-embedded tissue specimens by Laosinchai-Wolf, Walairat, Ye, Fei, Tran, Vu, Yang, Zhe, White, Roxanna, Bloom, Kenneth, Choppa, Paul, Labourier, Emmanuel

“…Colorectal cancer patients harbouring KRAS mutations in codon 12 or 13 do not benefit from current anti-epidermal growth factor receptor (EGFR) monoclonal…”
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The Oncomine Cancer Research Panel, a scalable next-generation sequencing system for relevant somatic variant assessment in solid tumors by Hovelson, Daniel H., Cani, Andi K., McDaniel, Andrew, Johnson, Bryan, Rhodes, Kate, Williams, Paul D, Bandla, Santhoshi, Choppa, Paul, Hyland, Fiona, Liu, Guoying, Schageman, Jeoffrey, Yadati, Venkata, Amin, Anmol, Cooney, Kathleen A., Feng, Felix Yi-Chung, Liu, Chia-Jen, Chinnaiyan, Arul M., Sadis, Seth, Rhodes, Dan, Tomlins, Scott A.

“…Abstract only…”
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Abstract 2220: Insight ALK ScreenTM, a highly sensitive and specific RT-qPCR first-line screening assay for comprehensive detection of all oncogenic anaplastic lymphoma kinase (ALK) fusions: clinical validation by Hout, David, Xue, Liquan, Choppa, Paul, Handshoe, John, Bloom, Kenneth, Ross, Douglas, Nickols, Josh, Morris, Stephan W.

“…Abstract More than 15 different ALK fusions (e.g., CLTC-ALK, multiple EML4-ALK variants, KIF5B-ALK, NPM-ALK, RanBP2-ALK, TFG-ALK, TPM4-ALK, others) cause…”
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Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice by Sherwood, James L, Brown, Helen, Rettino, Alessandro, Schreieck, Amelie, Clark, Graeme, Claes, Bart, Agrawal, Bhuwnesh, Chaston, Ria, Kong, Benjamin S G, Choppa, Paul, Nygren, Anders O H, Deras, Ina L, Kohlmann, Alexander

“…Click here and here to see the linked articles IntroductionThis study assessed KRAS mutation detection and functional characteristics across 13 distinct…”
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Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors12 by Hovelson, Daniel H., McDaniel, Andrew S., Cani, Andi K., Johnson, Bryan, Rhodes, Kate, Williams, Paul D., Bandla, Santhoshi, Bien, Geoffrey, Choppa, Paul, Hyland, Fiona, Gottimukkala, Rajesh, Liu, Guoying, Manivannan, Manimozhi, Schageman, Jeoffrey, Ballesteros-Villagrana, Efren, Grasso, Catherine S., Quist, Michael J., Yadati, Venkata, Amin, Anmol, Siddiqui, Javed, Betz, Bryan L., Knudsen, Karen E., Cooney, Kathleen A., Feng, Felix Y., Roh, Michael H., Nelson, Peter S., Liu, Chia-Jen, Beer, David G., Wyngaard, Peter, Chinnaiyan, Arul M., Sadis, Seth, Rhodes, Daniel R., Tomlins, Scott A.

“…Next-generation sequencing (NGS) has enabled genome-wide personalized oncology efforts at centers and companies with the specialty expertise and infrastructure…”
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Evaluation of MMR Concordance Based on Either International Scale (IS) or National Comprehensive Cancer Network (NCCN) Criteria Using Reconstructed “Virtual” CML Patient Profiles From the REVEAL BCR-ABL Methods Comparison Study by Reddy, Poluru L., Choppa, Paul, Moradian, Mike M., Potter, Nicholas T., Quigley, Michael M., Watt, Christopher D., Höfling, Holger, Manning, Brian, Mignault, Andre, Mullaney, Brian, Ossa, Diego, Stein, Andrew, Wang, Sha-Sha, Yang, Feng, Wetzler, Meir

“…Abstract 3542 Achieving major molecular response (MMR) is an important milestone in chronic myeloid leukemia (CML) therapy. MMR has been defined as a 3-log…”
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Minimizing cancer risk using molecular techniques: a review by Vojdani, A, Ghoneum, M, Choppa, P

“…This review article summarizes molecular markers that can signal enhanced risk of cancer and provide clinicians with these clues in order to attempt the use of…”
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