Search Results - "Choong, Xun"

Dissecting Alzheimer disease in Down syndrome using mouse models by Choong, Xun Yu, Tosh, Justin L, Pulford, Laura J, Fisher, Elizabeth M C

“…Down syndrome (DS) is a common genetic condition caused by the presence of three copies of chromosome 21 (trisomy 21). This greatly increases the risk of…”
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Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP by Wiseman, Frances K, Pulford, Laura J, Barkus, Chris, Liao, Fan, Portelius, Erik, Webb, Robin, Chávez-Gutiérrez, Lucia, Cleverley, Karen, Noy, Sue, Sheppard, Olivia, Collins, Toby, Powell, Caroline, Sarell, Claire J, Rickman, Matthew, Choong, Xun, Tosh, Justin L, Siganporia, Carlos, Whittaker, Heather T, Stewart, Floy, Szaruga, Maria, Murphy, Michael P, Blennow, Kaj, de Strooper, Bart, Zetterberg, Henrik, Bannerman, David, Holtzman, David M, Tybulewicz, Victor L J, Fisher, Elizabeth M C

“…Wiseman et al. show that triplication of genes other than APP is sufficient to exacerbate Aβ deposition and associated cognitive changes in a mouse model of…”
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Using primary neurons from transgenic mice to identify genes on human chromosome 21 influencing Alzheimer's neuropathology by Choong, Xun Yu, Raha, Alex, Tybulewicz, Victor, Wiseman, Frances, Fisher, Elizabeth

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P1–106: Using primary neurons from transgenic mice to identify genes on human chromosome 21 influencing Alzheimer's neuropathology by Choong, Xun Yu, Raha, Alex, Tybulewicz, Victor, Wiseman, Frances, Fisher, Elizabeth

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The relationship between perioperative markers of the systemic inflammatory response and postoperative complications in patients undergoing curative resection of colon cancer by Knight, Katrina, Choong, Jia Xun, Roxburgh, Campbell SD, Horgan, Paul G., McMillan, Donald C.

“…Abstract only 75 Background: Surgical resection remains the mainstay of treatment for patients with potentially curable colorectal cancer (CRC). However, it…”
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Multidisciplinary management of anal intraepithelial neoplasia and rate of progression to cancer: A retrospective cohort study by Knight, Katrina, Al-Wahid, Muhammed, Choong, Jia Xun, Burton, Kevin, Lindsay, Rhona, McKee, Ruth F., Anderson, John H., Roxburgh, Campbell SD

“…To describe the regional burden of AIN and rate of progression to cancer in patients managed in specialist and non-specialist clinic settings. Patients with a…”
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