Search Results - "Choo, Linda"
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New genetic predictors for abacavir tolerance in HLA-B57:01 positive individuals
Published in Human immunology (01-06-2020)“…Abacavir hypersensitivity syndrome (ABC HSS) is strongly associated with carriage of human leukocyte antigen (HLA)-B*57:01, which has a 100% negative…”
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Journal Article -
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Identifying Patient-Specific Epstein-Barr Nuclear Antigen-1 Genetic Variation and Potential Autoreactive Targets Relevant to Multiple Sclerosis Pathogenesis
Published in PloS one (05-02-2016)“…Epstein-Barr virus (EBV) infection represents a major environmental risk factor for multiple sclerosis (MS), with evidence of selective expansion of…”
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Journal Article -
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A low‐cost, sensitive and specific PCR‐based tool for rapid clinical detection of HLA‐B35 alleles associated with delayed drug hypersensitivity reactions
Published in HLA (01-12-2022)“…HLA (HLA) alleles are risk factors for CD8+ T‐cell‐mediated drug hypersensitivity reactions. However, as most HLA associations are incompletely predictive…”
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A Rapid Allele-Specific Assay for HLA-A32:01 to Identify Patients at Risk for Vancomycin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms
Published in The Journal of molecular diagnostics : JMD (01-09-2019)“…Human leukocyte antigen (HLA) alleles have been implicated as risk factors for immune-mediated adverse drug reactions. The authors recently reported a strong…”
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Journal Article -
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Identifying Patient-Specific Epstein-Barr Nuclear Antigen-1 Genetic Variation and Potential Autoreactive Targets Relevant to Multiple Sclerosis Pathogenesis: e0147567
Published in PloS one (01-02-2016)“…Background Epstein-Barr virus (EBV) infection represents a major environmental risk factor for multiple sclerosis (MS), with evidence of selective expansion of…”
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Journal Article -
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Visualising Antigen-Specific T-Cells During Primary and Persistent Infection with Epstein-Barr Virus
Published 01-01-1999“…Cytotoxic T lymphocytes play an important role in mediating host immune reactions to viruses and other pathogens. Selective mechanisms operate during V(D)J…”
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Dissertation