Search Results - "Chong, Trevor T J"
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Neurocomputational mechanisms underlying subjective valuation of effort costs
Published in PLoS biology (24-02-2017)“…In everyday life, we have to decide whether it is worth exerting effort to obtain rewards. Effort can be experienced in different domains, with some tasks…”
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Dopamine and reward: a view from the prefrontal cortex
Published in Behavioural pharmacology (01-10-2018)“…The prefrontal cortex (PFC) is a heterogeneous area that is critical to reward-based decision-making. In particular, the dorsal anterior cingulate cortex,…”
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3
Exercise‐induced cortical disinhibition mediates the relationship between fitness and memory in older adults
Published in The Journal of physiology (01-06-2024)“…Regular exercise benefits learning and memory in older adults, but the neural mechanisms mediating these effects remain unclear. Evidence in young adults…”
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4
Ageing attenuates exercise‐enhanced motor cortical plasticity
Published in The Journal of physiology (01-12-2023)“…Cardiorespiratory exercise is known to modulate motor cortical plasticity in young adults, but the influence of ageing on this relationship is unknown. Here,…”
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Choosing increases the value of non-instrumental information
Published in Scientific reports (22-04-2021)“…Curiosity pervades all aspects of human behaviour and decision-making. Recent research indicates that the value of information is determined by its propensity…”
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fMRI Adaptation Reveals Mirror Neurons in Human Inferior Parietal Cortex
Published in Current biology (28-10-2008)“…Mirror neurons, as originally described in the macaque, have two defining properties [1, 2]: They respond specifically to a particular action (e.g., bringing…”
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Associations of body habitus and its changes with incident dementia in older adults
Published in Journal of the American Geriatrics Society (JAGS) (01-04-2024)“…Background This study examined the associations of body mass index (BMI) and waist circumference (WC), as well as their short‐ and long‐term changes over time,…”
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Acute exercise as a modifier of neocortical plasticity and aperiodic activity in the visual cortex
Published in Scientific reports (09-05-2023)“…Long-term potentiation (LTP) is a form of neuroplasticity commonly implicated in mechanistic models of learning and memory. Acute exercise can boost LTP in the…”
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Model‐based and model‐free mechanisms in methamphetamine use disorder
Published in Addiction biology (01-01-2024)“…People with methamphetamine use disorder (MUD) struggle to shift their behaviour from methamphetamine‐orientated habits to goal‐oriented choices. The…”
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Standardised images of novel objects created with generative adversarial networks
Published in Scientific data (02-09-2023)“…An enduring question in cognitive science is how perceptually novel objects are processed. Addressing this issue has been limited by the absence of a…”
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Association of Dual Decline in Cognition and Gait Speed With Risk of Dementia in Older Adults
Published in JAMA network open (02-05-2022)“…Dual decline in gait speed and cognition has been found to be associated with increased dementia risk in previous studies. However, it is unclear if risks are…”
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Are methamphetamine users compulsive? Faulty reinforcement learning, not inflexibility, underlies decision making in people with methamphetamine use disorder
Published in Addiction biology (01-07-2021)“…Methamphetamine use disorder involves continued use of the drug despite negative consequences. Such ‘compulsivity’ can be measured by reversal learning tasks,…”
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D2 receptor blockade eliminates exercise-induced changes in cortical inhibition and excitation
Published in Brain stimulation (01-05-2023)“…Although cardiorespiratory exercise is known to affect cortical excitatory and inhibitory activity, the neurochemical mechanisms driving this effect are poorly…”
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Combination of gait speed and grip strength to predict cognitive decline and dementia
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2022)“…Introduction To determine whether slowed gait and weakened grip strength independently, or together, better identify risk of cognitive decline or dementia…”
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High-intensity acute exercise impacts motor learning in healthy older adults
Published in NPJ science of learning (17-02-2024)“…Healthy aging is associated with changes in motor sequence learning, with some studies indicating decline in motor skill learning in older age. Acute…”
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Lifestyle Enrichment in Later Life and Its Association With Dementia Risk
Published in JAMA network open (03-07-2023)“…Lifestyles enriched with socially and mentally stimulating activities in older age may help build cognitive reserve and reduce dementia risk. To investigate…”
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Selective attention modulates inferior frontal gyrus activity during action observation
Published in NeuroImage (Orlando, Fla.) (01-03-2008)“…Our ability to recognize the actions of others is subserved by a complex network of brain areas, including the inferior frontal gyrus (IFG), inferior parietal…”
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Multidimensional Apathy: The Utility of the Dimensional Apathy Scale in Huntington's Disease
Published in Movement disorders clinical practice (Hoboken, N.J.) (01-04-2021)“…Background Apathy is a disorder of motivation common to Huntington's disease (HD). Recent conceptual frameworks suggest that apathy is not unitary but consists…”
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Grip strength, gait speed, and trajectories of cognitive function in community‐dwelling older adults: A prospective study
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-01-2023)“…Introduction This study investigated whether grip strength and gait speed predict cognitive aging trajectories and examined potential sex‐specific…”
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The role of selective attention in matching observed and executed actions
Published in Neuropsychologia (01-02-2009)“…Substantial evidence suggests that observed actions can engage their corresponding motor representations within the observer. It is currently believed that…”
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