Search Results - "Chong, Suyinn"

Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model by Kaminen-Ahola, Nina, Ahola, Arttu, Maga, Murat, Mallitt, Kylie-Ann, Fahey, Paul, Cox, Timothy C, Whitelaw, Emma, Chong, Suyinn

“…Recent studies have shown that exposure to some nutritional supplements and chemicals in utero can affect the epigenome of the developing mouse embryo,…”
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Epigenetic regulation in male germ cells by Zamudio, Natasha M, Chong, Suyinn, O'Bryan, Moira K

“…In recent years, it has become increasingly clear that epigenetic regulation of gene expression is critical during spermatogenesis. In this review, the…”
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Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise by Whitelaw, Nadia C, Chong, Suyinn, Morgan, Daniel K, Nestor, Colm, Bruxner, Timothy J, Ashe, Alyson, Lambley, Eleanore, Meehan, Richard, Whitelaw, Emma

“…Inbred individuals reared in controlled environments display considerable variance in many complex traits but the underlying cause of this intangible variation…”
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Gene expression in the mouse brain following early pregnancy exposure to ethanol by Zhang, Christine R., Chong, Suyinn

“…Exposure to alcohol during early embryonic or fetal development has been linked with a variety of adverse outcomes, the most common of which are structural and…”
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DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription by Zamudio, Natasha M, Scott, Hamish S, Wolski, Katja, Lo, Chi-Yi, Law, Charity, Leong, Dillon, Kinkel, Sarah A, Chong, Suyinn, Jolley, Damien, Smyth, Gordon K, de Kretser, David, Whitelaw, Emma, O'Bryan, Moira K

“…Previous studies on the epigenetic regulator DNA methyltransferase 3-Like (DNMT3L), have demonstrated it is an essential regulator of paternal imprinting and…”
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Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro by Tagoh, Hiromi, Melnik, Svitlana, Lefevre, Pascal, Chong, Suyinn, Riggs, Arthur D., Bonifer, Constanze

“…In order to gain insights in the true molecular mechanisms involved in cell fate decisions, it is important to study the molecular details of gene activation…”
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How the mouse got its spots by Blewitt, Marnie E., Chong, Suyinn, Whitelaw, Emma

“…One's ultimate phenotype is the result of a combination of genotype and environment, and includes a poorly understood component termed ‘developmental noise’…”
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A Functional Chromatin Domain Does Not Resist X Chromosome Inactivation: Silencing of cLys Correlates with Methylation of a Dual Promoter-Replication Origin by Chong, Suyinn, Kontaraki, Joanna, Bonifer, Constanze, Riggs, Arthur D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulatory effects of GR Exon 1 variants on differential placental glucocorticoid receptor protein isoform in pregnancies complicated with asthma by Saif, Zarqa, Chong, Suyinn, Clifton, Vicki

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Radiological studies of fetal alcohol spectrum disorders in humans and animal models: An updated comprehensive review by Nguyen, Van T, Chong, Suyinn, Tieng, Quang M, Mardon, Karine, Galloway, Graham J, Kurniawan, Nyoman D

“…Abstract Fetal Alcohol Spectrum Disorders encompass a wide range of birth defects in children born to mothers who consumed alcohol during pregnancy. Typical…”
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Transgenerational inheritance of epigenetic states at the murine AxinFu allele occurs after maternal and paternal transmission by Rakyan, Vardhman K, Chong, Suyinn, Champ, Marnie E, Cuthbert, Peter C

“…Phenotypic variation that cannot be explained by genetic or environmental heterogeneity has intrigued geneticists for decades. The molecular basis of this…”
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Epigenetic germline inheritance by Chong, Suyinn, Whitelaw, Emma

“…Our increased knowledge of epigenetic reprogramming supports the idea that epigenetic marks are not always completely cleared between generations. Incomplete…”
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Heritable germline epimutation is not the same as transgenerational epigenetic inheritance by Chong, Suyinn, Youngson, Neil A, Whitelaw, Emma

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Early gestational ethanol exposure in mice: Effects on brain structure, energy metabolism and adiposity in adult offspring by Zhang, Christine R., Kurniawan, Nyoman D., Yamada, Lisa, Fleming, Whitney, Kaminen-Ahola, Nina, Ahola, Arttu, Galloway, Graham, Chong, Suyinn

“…We examined whether an early-life event – ethanol exposure in the initial stages of pregnancy – affected offspring brain structure, energy metabolism, and body…”
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Effects of periconceptional maternal alcohol intake and a postnatal high-fat diet on obesity and liver disease in male and female rat offspring by Gårdebjer, Emelie M, Cuffe, James S M, Ward, Leigh C, Steane, Sarah, Anderson, Stephen T, Dorey, Emily S, Kalisch-Smith, Jacinta I, Pantaleon, Marie, Chong, Suyinn, Yamada, Lisa, Wlodek, Mary E, Bielefeldt-Ohmann, Helle, Moritz, Karen M

“…The effects of maternal alcohol consumption around the time of conception on offspring are largely unknown and difficult to determine in a human population…”
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Tuning In to Noise: Epigenetics and Intangible Variation by Whitelaw, Nadia C., Chong, Suyinn, Whitelaw, Emma

“…In this special issue of Developmental Cell, we discuss the role of chromatin in phenotypic variation as a counterpoint to the reviews on chromatin dynamics in…”
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Modifiers of epigenetic reprogramming show paternal effects in the mouse by Whitelaw, Emma, Chong, Suyinn, Vickaryous, Nicola, Ashe, Alyson, Zamudio, Natasha, Youngson, Neil, Hemley, Sarah, Stopka, Tomas, Skoultchi, Arthur, Matthews, Jacqui, Scott, Hamish S, de Kretser, David, O'Bryan, Moira, Blewitt, Marnie

“…There is increasing evidence that epigenetic information can be inherited across generations in mammals, despite extensive reprogramming both in the gametes…”
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Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission by Rakyan, Vardhman K, Chong, Suyinn, Champ, Marnie E, Cuthbert, Peter C, Morgan, Hugh D, Luu, Keith V K, Whitelaw, Emma

“…Phenotypic variation that cannot be explained by genetic or environmental heterogeneity has intrigued geneticists for decades. The molecular basis of this…”
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Magnetic Resonance Imaging and Micro-Computed Tomography reveal brain morphological abnormalities in a mouse model of early moderate prenatal ethanol exposure by Nguyen, Van T., Tieng, Quang M., Mardon, Karine, Zhang, Christine, Chong, Suyinn, Galloway, Graham J., Kurniawan, Nyoman D.

“…This study investigated the effects of early moderate prenatal ethanol exposure (PEE) on the brain in a mouse model that mimics a scenario in humans, whereby…”
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Early gestational exposure to moderate concentrations of ethanol alters adult behaviour in C57BL/6J mice by Sanchez Vega, Michelle C., Chong, Suyinn, Burne, Thomas H.J.

“…•We examined the effects of a moderate dose ethanol exposure during the first eight days of gestation in mice.•Ethanol-exposed mice showed increased…”
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