Search Results - "Chong, Shin Yen"
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H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress
Published in Nature communications (10-02-2020)“…Transcription-replication conflicts (TRCs) occur when intensive transcriptional activity compromises replication fork stability, potentially leading to gene…”
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Green tea extract promotes DNA repair in a yeast model
Published in Scientific reports (07-03-2019)“…Green tea polyphenols may protect cells from UV damage through antioxidant activities and by stimulating the removal of damaged or cross-linked DNA. Recently,…”
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Histone dynamics during DNA replication stress
Published in Journal of biomedical science (19-06-2021)“…Accurate and complete replication of the genome is essential not only for genome stability but also for cell viability. However, cells face constant threats to…”
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Tangeretin Sensitizes SGS1-Deficient Cells by Inducing DNA Damage
Published in Journal of agricultural and food chemistry (03-07-2013)“…Tangeretin, a polymethoxyflavone found in citrus peel, has been shown to have antiatherogenic, anti-inflammatory, and anticarcinogenic properties. However, the…”
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Induction of GADD45α expression contributes to the anti-proliferative effects of polymethoxyflavones on colorectal cancer cells
Published in Journal of functional foods (01-04-2013)“…Polymethoxyflavones (PMFs), such as nobiletin and tangeretin, have a high cellular uptake rate, on account of their hydrophobicity. Nobiletin has been shown to…”
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Mutation at a distance caused by homopolymeric guanine repeats in Saccharomyces cerevisiae
Published in Science advances (01-05-2016)“…Mutation provides the raw material from which natural selection shapes adaptations. The rate at which new mutations arise is therefore a key factor that…”
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