Search Results - "Chong, Pan"
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CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy
Published in Journal of experimental & clinical cancer research (31-03-2022)“…Adoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and…”
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2
Combination strategies to maximize the benefits of cancer immunotherapy
Published in Journal of hematology and oncology (27-09-2021)“…Abstract Immunotherapies such as immune checkpoint blockade (ICB) and adoptive cell therapy (ACT) have revolutionized cancer treatment, especially in patients…”
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3
Humanized mice in studying efficacy and mechanisms of PD‐1‐targeted cancer immunotherapy
Published in The FASEB journal (01-03-2018)“…Establishment of an in vivo small animal model of human tumor and human immune system interaction would enable preclinical investigations into the mechanisms…”
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4
Human peripheral blood derived mesenchymal stem cells demonstrate similar characteristics and chondrogenic differentiation potential to bone marrow derived mesenchymal stem cells
Published in Journal of orthopaedic research (01-04-2012)“…The use of mesenchymal stem cells (MSCs) for cartilage repair has generated much interest owing to their multipotentiality. However, their significant presence…”
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5
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
Published in Nature communications (14-09-2020)“…Although the efficacy of cancer radiotherapy (RT) can be enhanced by targeted immunotherapy, the immunosuppressive factors induced by radiation on tumor cells…”
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Phase Ib trial of reformulated niclosamide with abiraterone/prednisone in men with castration-resistant prostate cancer
Published in Scientific reports (18-03-2021)“…Niclosamide has preclinical activity against a wide range of cancers. In prostate cancer, it inhibits androgen receptor variant 7 and synergizes with…”
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7
Near-field thermal rectification via an InSb/graphene/3C–SiC-nanowire heterostructure
Published in International journal of thermal sciences (01-12-2023)“…Thermal rectifiers allow asymmetric heat flux when the temperature bias between two terminals is reversed. Based on the near-field radiative heat transfer, the…”
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8
Wavelet Networks in Power Transformers Diagnosis Using Dissolved Gas Analysis
Published in IEEE transactions on power delivery (01-01-2009)“…Wavelet networks (WNs) are an efficient model of nonlinear signal processing developed in recent years. This paper presents a comparative study of WN…”
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9
MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway status
Published in International journal of cancer (01-06-2012)“…MiR‐34a is a downstream effector of p53 that has been shown to target several molecules associated with cell cycle and cell survival pathways. As alterations…”
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10
Increasing cure rates of solid tumors by immune checkpoint inhibitors
Published in Experimental hematology & oncology (16-01-2023)“…Immunotherapy has become the central pillar of cancer therapy. Immune checkpoint inhibitors (ICIs), a major category of tumor immunotherapy, reactivate…”
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11
Broadband directional thermal radiator with flexible intensity–directivity tunability in the whole visible spectrum
Published in Applied physics letters (10-07-2023)“…Controlling spectral and directional distributions of thermal radiation plays an important role in designing functional structures for thermal management. As a…”
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12
Miniature optoelectronic compound eye camera
Published in Nature communications (26-09-2022)“…Inspired by insect compound eyes (CEs) that feature unique optical schemes for imaging, there has recently been growing interest in developing optoelectronic…”
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13
A transformable nanoplatform with multiple therapeutic and immunostimulatory properties for treatment of advanced cancers
Published in Biomaterials (01-08-2023)“…Cancer is a complex pathological phenomenon that needs to be treated from different aspects. Herein, we developed a size/charge dually transformable…”
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14
Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer
Published in Molecular cancer therapeutics (01-08-2017)“…Activation of the androgen receptor (AR) and its splice variants is linked to advanced prostate cancer and drives resistance to antiandrogens. The roles of AR…”
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15
Insights on recent innovations in bladder cancer immunotherapy
Published in Cancer cytopathology (01-09-2022)“…Bladder carcinoma is the most common genitourinary cancer, with a high prevalence and global incidence. In addition to early detection by cytology, the…”
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Comparing the Therapeutic Potential of Stem Cells and their Secretory Products in Regenerative Medicine
Published in Stem cells international (2021)“…Cell therapy involves the transplantation of human cells to replace or repair the damaged tissues and modulate the mechanisms underlying disease initiation and…”
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17
Unlocking the potential of organoids in cancer treatment and translational research: An application of cytologic techniques
Published in Cancer cytopathology (01-02-2024)“…Patient‐derived organoid models hold promise for advancing clinical cancer research, including diagnosis and personalized and precision medicine approaches,…”
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18
Effects of Acid–Base Properties of Ammonium Salt Electrolyte on Electrochemical Surface Activation of Carbon Fibers
Published in Fibers and polymers (01-10-2023)“…Surface activation is an essential process in carbon fiber preparation for surface inertness of carbon fibers. In this study, X-ray photoelectron, Raman…”
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A phase 2 clinical trial of everolimus plus bicalutamide for castration‐resistant prostate cancer
Published in Cancer (15-06-2016)“…BACKGROUND The mammalian target of rapamycin (mTOR) pathway is up‐regulated in castration‐resistant prostate cancer (CRPC). Nevertheless, inhibition of mTOR is…”
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The Phosphatidylinositol 3-Kinase Pathway as a Potential Therapeutic Target in Bladder Cancer
Published in Clinical cancer research (01-11-2017)“…Activation of the PI3K pathway occurs in over 40% of bladder urothelial cancers. The aim of this study is to determine the therapeutic potential, the…”
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