Search Results - "Chong, James J.H."

Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair by Fernandes, Sarah, Chong, James J.H., Paige, Sharon L., Iwata, Mineo, Torok-Storb, Beverly, Keller, Gordon, Reinecke, Hans, Murry, Charles E.

“…Cardiomyocytes derived from human embryonic stem cells (hESC-CMs) can improve the contractility of injured hearts. We hypothesized that mesodermal…”
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Cell Therapy for Left Ventricular Dysfunction: An Overview for Cardiac Clinicians by Chong, James J.H., MBBS, PhD

“…Abstract Cell therapies specifically targeting heart failure could greatly decrease morbidity and burgeoning health care costs worldwide. Due to the great…”
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Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts by Chong, James J. H., Yang, Xiulan, Don, Creighton W., Minami, Elina, Liu, Yen-Wen, Weyers, Jill J., Mahoney, William M., Van Biber, Benjamin, Cook, Savannah M., Palpant, Nathan J., Gantz, Jay A., Fugate, James A., Muskheli, Veronica, Gough, G. Michael, Vogel, Keith W., Astley, Cliff A., Hotchkiss, Charlotte E., Baldessari, Audrey, Pabon, Lil, Reinecke, Hans, Gill, Edward A., Nelson, Veronica, Kiem, Hans-Peter, Laflamme, Michael A., Murry, Charles E.

“…Regeneration of the heart muscle after myocardial infarction with cardiomyocytes derived from human embryonic stem cells is demonstrated in non-human primates,…”
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Adult Cardiac-Resident MSC-like Stem Cells with a Proepicardial Origin by Chong, James J.H., Chandrakanthan, Vashe, Xaymardan, Munira, Asli, Naisana S., Li, Joan, Ahmed, Ishtiaq, Heffernan, Corey, Menon, Mary K., Scarlett, Christopher J., Rashidianfar, Amirsalar, Biben, Christine, Zoellner, Hans, Colvin, Emily K., Pimanda, John E., Biankin, Andrew V., Zhou, Bin, Pu, William T., Prall, Owen W.J., Harvey, Richard P.

“…Colony-forming units – fibroblast (CFU-Fs), analogous to those giving rise to bone marrow (BM) mesenchymal stem cells (MSCs), are present in many organs,…”
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Cardiac regeneration using pluripotent stem cells—Progression to large animal models by Chong, James J.H., Murry, Charles E.

“…Pluripotent stem cells (PSCs) have indisputable cardiomyogenic potential and therefore have been intensively investigated as a potential cardiac regenerative…”
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Recombinant Adeno-Associated Viral Vector-Mediated Gene Transfer of hTBX18 Generates Pacemaker Cells from Ventricular Cardiomyocytes by Farraha, Melad, Rao, Renuka, Igoor, Sindhu, Le, Thi Y. L., Barry, Michael A., Davey, Christopher, Kok, Cindy, Chong, James J.H., Kizana, Eddy

“…Sinoatrial node dysfunction can manifest as bradycardia, leading to symptoms of syncope and sudden cardiac death. Electronic pacemakers are the current…”
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Cardiac Autonomic Neuropathy Is Not Reversed by Euglycemia Following Islet Transplantation by Deshmukh, Tejas, Emerson, Peter, Anderson, Patricia, Kizana, Eddy, O’Connell, Philip J., Holmes-Walker, D. Jane, Chong, James J.H.

“…BACKGROUND:Cardiac autonomic neuropathy (CAN) is a significant cause of morbidity and mortality for people with Type 1 (T1D) and Type 2 (T2D) diabetes. Heart…”
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Growth factor therapy for cardiac repair: an overview of recent advances and future directions by White, Samuel J., Chong, James J. H.

“…Heart disease represents a significant public health burden and is associated with considerable morbidity and mortality at the level of the individual. Current…”
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Letter by Murry et al Regarding Article, “Embryonic Stem Cell–Derived Cardiac Myocytes Are Not Ready for Human Trials” by Murry, Charles E, Chong, James J.H, Laflamme, Michael A

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Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes by Kok, Cindy Y., Tsurusaki, Shinya, Cabanes-Creus, Marti, Igoor, Sindhu, Rao, Renuka, Skelton, Rhys, Liao, Sophia H.Y., Ginn, Samantha L., Knight, Maddison, Scott, Suzanne, Mietzsch, Mario, Fitzsimmons, Rebecca, Miller, Jessica, Mohamed, Tamer M.A., McKenna, Robert, Chong, James J.H., Hill, Adam P., Hudson, James E., Alexander, Ian E., Lisowski, Leszek, Kizana, Eddy

“…Recombinant adeno-associated viruses (rAAVs) have emerged as one of the most promising gene therapy vectors that have been successfully used in pre-clinical…”
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Therapeutic Prospects of Gene Therapy for Atrial Fibrillation by Farraha, Melad, BEng, BMed. Sci, MEng, Chong, James J.H., MBBS, PhD, FRACP, Kizana, Eddy, MBBS, PhD, FRACP

“…Atrial Fibrillation (AF) is one of the most common types of cardiac arrhythmias experienced in clinical practice, increasing the risk of stroke, dementia,…”
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Developmental origins and lineage descendants of endogenous adult cardiac progenitor cells by Chong, James J.H., Forte, Elvira, Harvey, Richard P.

“…Mammalian hearts carry a number of primitive stem cell-like populations, although the magnitude of their contribution to tissue homeostasis and repair remains…”
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Comparison of Left Ventricular Ejection Fraction and Inducible Ventricular Tachycardia in ST-Elevation Myocardial Infarction Treated by Primary Angioplasty Versus Thrombolysis by Chong, James J.H., MD, Ganesan, Anand N., MD, PhD, Eipper, Vicki, Kovoor, Pramesh, MD, PhD

“…Electrophysiologic studies predict the risk for sudden death after myocardial infarction (MI). Although primary angioplasty has become the preferred method of…”
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Supraventricular ectopy and recurrence of atrial fibrillation after electrical cardioversion by Chong, James J H, Kumar, Saurabh, Thomas, Liza, Thomas, Stuart

“…Paroxysmal atrial fibrillation (AF) is usually preceded by a premature atrial complex (PAC). We hypothesized that patients with a high frequency of atrial…”
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Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia by Perdomo, José, Leung, Halina H. L., Ahmadi, Zohra, Yan, Feng, Chong, James J. H., Passam, Freda H., Chong, Beng H.

“…Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to heparins, characterized by thrombocytopenia and often severe thrombosis with…”
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Inflammation: the next target for secondary prevention in coronary artery disease by Kazi, Samia, Chong, James J H, Chow, Clara K

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Ghrelin mediated cardioprotection using in vitro models of oxidative stress by Kok, Cindy Y., Ghossein, George, Igoor, Sindhu, Rao, Renuka, Titus, Tracy, Tsurusaki, Shinya, Chong, James JH, Kizana, Eddy

“…Ghrelin is commonly known as the ‘hunger hormone’ due to its role in stimulating food intake in humans. However, the roles of ghrelin extend beyond regulating…”
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Cardiac Cell Therapy with Pluripotent Stem Cell-Derived Cardiomyocytes: What Has Been Done and What Remains to Do? by Selvakumar, Dinesh, Reyes, Leila, Chong, James J. H.

“…Purpose of Review Exciting pre-clinical data presents pluripotent stem cell-derived cardiomyocytes (PSC-CM) as a novel therapeutic prospect following…”
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NETosis and thrombosis in vaccine-induced immune thrombotic thrombocytopenia by Leung, Halina H. L., Perdomo, Jose, Ahmadi, Zohra, Zheng, Shiying S., Rashid, Fairooj N., Enjeti, Anoop, Ting, Stephen B., Chong, James J. H., Chong, Beng H.

“…Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet serious adverse effect of the adenoviral vector vaccines ChAdOx1 nCoV-19 (AstraZeneca)…”
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Therapeutic Angiogenesis Using Growth Factors After Myocardial Infarction: From Recombinant Proteins to Gene Therapies and Beyond by Deshmukh, Tejas, Chong, James J H

“…Ischaemic heart disease is the primary cause of death worldwide with myocardial infarction (MI) contributing to significant morbidity and mortality. The human…”
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