Search Results - "Chong, Amanda"

Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression by Mitchell, Ruth E, Hartley, April E, Walker, Venexia M, Gkatzionis, Apostolos, Yarmolinsky, James, Bell, Joshua A, Chong, Amanda H W, Paternoster, Lavinia, Tilling, Kate, Smith, George Davey

“…Genetic studies of disease progression can be used to identify factors that may influence survival or prognosis, which may differ from factors that influence…”
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Effects of poly(3-hydroxybutyrate) [P(3HB)] coating on the bacterial communities of artificial structures by Chai, Yee Jean, Syauqi, Taufiq Ahmad, Sudesh, Kumar, Ee, Tan Leng, Ban, Cheah Chee, Kar Mun, Amanda Chong, Anne Strain, Elisabeth Marijke, Merican, Faradina, Rahim, Masazurah A, Md Salleh, Kaharudin, Yin, Chee Su

“…The expanding urbanization of coastal areas has led to increased ocean sprawl, which has had both physical and chemical adverse effects on marine and coastal…”
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Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection by Mentzer, Alexander J., O’Connor, Daniel, Bibi, Sagida, Chelysheva, Irina, Clutterbuck, Elizabeth A., Demissie, Tesfaye, Dinesh, Tanya, Edwards, Nick J., Felle, Sally, Feng, Shuo, Flaxman, Amy L., Karp-Tatham, Eleanor, Li, Grace, Liu, Xinxue, Marchevsky, Natalie, Godfrey, Leila, Makinson, Rebecca, Bull, Maireid B., Fowler, Jamie, Alamad, Bana, Malinauskas, Tomas, Chong, Amanda Y., Sanders, Katherine, Shaw, Robert H., Voysey, Merryn, Snape, Matthew D., Pollard, Andrew J., Lambe, Teresa, Knight, Julian C.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine immunogenicity varies between individuals, and immune responses correlate with vaccine…”
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Pre-admission interventions (prehabilitation) to improve outcome after major elective surgery: a systematic review and meta-analysis by Perry, Rachel, Herbert, Georgia, Atkinson, Charlotte, England, Clare, Northstone, Kate, Baos, Sarah, Brush, Tim, Chong, Amanda, Ness, Andy, Harris, Jessica, Haase, Anne, Shah, Sanjoy, Pufulete, Maria

“…ObjectiveTo determine the benefits and harms of pre-admission interventions (prehabilitation) on postoperative outcomes in patients undergoing major elective…”
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Investigating the effect of sexual behaviour on oropharyngeal cancer risk: a methodological assessment of Mendelian randomization by Gormley, Mark, Dudding, Tom, Kachuri, Linda, Burrows, Kimberley, Chong, Amanda H W, Martin, Richard M, Thomas, Steven J, Tyrrell, Jessica, Ness, Andrew R, Brennan, Paul, Munafò, Marcus R, Pring, Miranda, Boccia, Stefania, Olshan, Andrew F, Diergaarde, Brenda, Hung, Rayjean J, Liu, Geoffrey, Tajara, Eloiza H, Severino, Patricia, Toporcov, Tatiana N, Lacko, Martin, Waterboer, Tim, Brenner, Nicole, Smith, George Davey, Vincent, Emma E, Richmond, Rebecca C

“…Human papilloma virus infection is known to influence oropharyngeal cancer (OPC) risk, likely via sexual transmission. However, sexual behaviour has been…”
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Genetic Analyses of Common Infections in the Avon Longitudinal Study of Parents and Children Cohort by Chong, Amanda H W, Mitchell, Ruth E, Hemani, Gibran, Davey Smith, George, Yolken, Robert H, Richmond, Rebecca C, Paternoster, Lavinia

“…The burden of infections on an individual and public health is profound. Many observational studies have shown a link between infections and the pathogenesis…”
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Mexican Biobank advances population and medical genomics of diverse ancestries by Sohail, Mashaal, Palma-Martínez, María J., Chong, Amanda Y., Quinto-Cortés, Consuelo D., Barberena-Jonas, Carmina, Medina-Muñoz, Santiago G., Ragsdale, Aaron, Delgado-Sánchez, Guadalupe, Cruz-Hervert, Luis Pablo, Ferreyra-Reyes, Leticia, Ferreira-Guerrero, Elizabeth, Mongua-Rodríguez, Norma, Canizales-Quintero, Sergio, Jimenez-Kaufmann, Andrés, Moreno-Macías, Hortensia, Aguilar-Salinas, Carlos A., Auckland, Kathryn, Cortés, Adrián, Acuña-Alonzo, Víctor, Gignoux, Christopher R., Wojcik, Genevieve L., Ioannidis, Alexander G., Fernández-Valverde, Selene L., Hill, Adrian V. S., Tusié-Luna, María Teresa, Mentzer, Alexander J., Novembre, John, García-García, Lourdes, Moreno-Estrada, Andrés

“…Latin America continues to be severely underrepresented in genomics research, and fine-scale genetic histories and complex trait architectures remain hidden…”
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A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy by Chong, Amanda Y., Brenner, Nicole, Jimenez-Kaufmann, Andres, Cortes, Adrian, Hill, Michael, Littlejohns, Thomas J., Gilchrist, James J., Fairfax, Benjamin P., Knight, Julian C., Hodel, Flavia, Fellay, Jacques, McVean, Gil, Moreno-Estrada, Andres, Waterboer, Tim, Hill, Adrian V.S., Mentzer, Alexander J.

“…Infectious agents contribute significantly to the global burden of diseases through both acute infection and their chronic sequelae. We leveraged the UK…”
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Genetic, lifestyle, and health-related characteristics of adults without celiac disease who follow a gluten-free diet: a population-based study of 124,447 participants by Littlejohns, Thomas J, Chong, Amanda Y, Allen, Naomi E, Arnold, Matthew, Bradbury, Kathryn E, Mentzer, Alexander J, Soilleux, Elizabeth J, Carter, Jennifer L

“…The number of gluten-free diet followers without celiac disease (CD) is increasing. However, little is known about the characteristics of these individuals. We…”
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Identification of host–pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank by Mentzer, Alexander J., Brenner, Nicole, Allen, Naomi, Littlejohns, Thomas J., Chong, Amanda Y., Cortes, Adrian, Almond, Rachael, Hill, Michael, Sheard, Simon, McVean, Gil, Collins, Rory, Hill, Adrian V. S., Waterboer, Tim

“…Certain infectious agents are recognised causes of cancer and other chronic diseases. To understand the pathological mechanisms underlying such relationships,…”
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Change in obesity‐related metabolic abnormalities associated with body mass index improvement through life‐style intervention: A meta‐regression by Matson, Rhys IB, Perry, Rachel, Hunt, Linda P, Chong, Amanda HW, Beynon, Rhona, Hamilton‐Shield, Julian, Birch, Laura

“…The reduction in body mass index standard deviation score (BMI‐SDS) associated with improvement in biomarkers relating to metabolic health in obese children is…”
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High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response by Mentzer, Alexander J., Dilthey, Alexander T., Pollard, Martin, Gurdasani, Deepti, Karakoc, Emre, Carstensen, Tommy, Muhwezi, Allan, Cutland, Clare, Diarra, Amidou, da Silva Antunes, Ricardo, Paul, Sinu, Smits, Gaby, Wareing, Susan, Kim, HwaRan, Pomilla, Cristina, Chong, Amanda Y., Brandt, Debora Y. C., Nielsen, Rasmus, Neaves, Samuel, Timpson, Nicolas, Crinklaw, Austin, Lindestam Arlehamn, Cecilia S., Rautanen, Anna, Kizito, Dennison, Parks, Tom, Auckland, Kathryn, Elliott, Kate E., Mills, Tara, Ewer, Katie, Edwards, Nick, Fatumo, Segun, Webb, Emily, Peacock, Sarah, Jeffery, Katie, van der Klis, Fiona R. M., Kaleebu, Pontiano, Vijayanand, Pandurangan, Peters, Bjorn, Sette, Alessandro, Cereb, Nezih, Sirima, Sodiomon, Madhi, Shabir A., Elliott, Alison M., McVean, Gil, Hill, Adrian V. S., Sandhu, Manjinder S.

“…How human genetic variation contributes to vaccine effectiveness in infants is unclear, and data are limited on these relationships in populations with African…”
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Letter to the Editor: Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection by Karp-Tatham, Eleanor, O’Neill, Callum R., Knight, Julian C., Mentzer, Alexander J., Chong, Amanda Y.

“…Research into HLA-B*15:01 association with asymptomatic SARS-CoV-2 infection has so far yielded contradicting results. Using the UK Biobank cohort, we found a…”
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Comparative genome analyses reveal distinct structure in the saltwater crocodile MHC by Jaratlerdsiri, Weerachai, Deakin, Janine, Godinez, Ricardo M, Shan, Xueyan, Peterson, Daniel G, Marthey, Sylvain, Lyons, Eric, McCarthy, Fiona M, Isberg, Sally R, Higgins, Damien P, Chong, Amanda Y, John, John St, Glenn, Travis C, Ray, David A, Gongora, Jaime

“…The major histocompatibility complex (MHC) is a dynamic genome region with an essential role in the adaptive immunity of vertebrates, especially antigen…”
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Materials and Processes of Eco-concrete Mixtures for Artificial Marine Habitats by Mun Chong, Amanda Kar, Ikrami Mutti, Mohd Alif, Cheah, Chee Ban, Yee, Jean Chai, Chee, Su Yin

“…Poor quality habitat profiles of artificial coastal structures for biodiversity growth compared to natural shore have led researchers to utilize ecological…”
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What change in body mass index is associated with improvement in percentage body fat in childhood obesity? A meta-regression by Birch, Laura, Perry, Rachel, Hunt, Linda P, Matson, Rhys, Chong, Amanda, Beynon, Rhona, Shield, Julian PH

“…ObjectiveUsing meta-regression this paper sets out the minimum change in body mass index-SD score (BMI-SDS) required to improve adiposity as percentage body…”
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Evolution and gene capture in ancient endogenous retroviruses - insights from the crocodilian genomes by Chong, Amanda Y, Kojima, Kenji K, Jurka, Jerzy, Ray, David A, Smit, Arian F A, Isberg, Sally R, Gongora, Jaime

“…Crocodilians are thought to be hosts to a diverse and divergent complement of endogenous retroviruses (ERVs) but a comprehensive investigation is yet to be…”
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Imputation Performance in Latin American Populations: Improving Rare Variants Representation With the Inclusion of Native American Genomes by Jiménez-Kaufmann, Andrés, Chong, Amanda Y, Cortés, Adrián, Quinto-Cortés, Consuelo D, Fernandez-Valverde, Selene L, Ferreyra-Reyes, Leticia, Cruz-Hervert, Luis Pablo, Medina-Muñoz, Santiago G, Sohail, Mashaal, Palma-Martinez, María J, Delgado-Sánchez, Gudalupe, Mongua-Rodríguez, Norma, Mentzer, Alexander J, Hill, Adrian V S, Moreno-Macías, Hortensia, Huerta-Chagoya, Alicia, Aguilar-Salinas, Carlos A, Torres, Michael, Kim, Hie Lim, Kalsi, Namrata, Schuster, Stephan C, Tusié-Luna, Teresa, Del-Vecchyo, Diego Ortega, García-García, Lourdes, Moreno-Estrada, Andrés

“…Current Genome-Wide Association Studies (GWAS) rely on genotype imputation to increase statistical power, improve fine-mapping of association signals, and…”
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Inferring the evolution of the major histocompatibility complex of wild pigs and peccaries using hybridisation DNA capture-based sequencing by Lee, Carol, Moroldo, Marco, Perdomo-Sabogal, Alvaro, Mach, Núria, Marthey, Sylvain, Lecardonnel, Jérôme, Wahlberg, Per, Chong, Amanda Y., Estellé, Jordi, Ho, Simon Y. W., Rogel-Gaillard, Claire, Gongora, Jaime

“…The major histocompatibility complex (MHC) is a key genomic model region for understanding the evolution of gene families and the co-evolution between host and…”
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Surveys of endogenous retroviruses (ERVs) in the freshwater crocodile (Crocodylus johnstoni) suggest that ERVs in Crocodylus spp. vary between species by Chong, Amanda Y., Kjeldsen, Shannon R., Gongora, Jaime

“…Endogenous retroviruses (ERVs) are one of many families of transposable elements present in vertebrate genomes. We have examined the ERV complement of the…”
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