Search Results - "Chompret, Agnes"

The Li–Fraumeni syndrome by Chompret, Agnès

“…Li–Fraumeni syndrome (LFS) has been the most common terminology used for the syndrome. It is a rare familial dominantly inherited cancer syndrome characterized…”
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Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy by Apetoh, Lionel, Ghiringhelli, François, Tesniere, Antoine, Obeid, Michel, Ortiz, Carla, Criollo, Alfredo, Mignot, Grégoire, Maiuri, M Chiara, Ullrich, Evelyn, Saulnier, Patrick, Yang, Huan, Amigorena, Sebastian, Ryffel, Bernard, Barrat, Franck J, Saftig, Paul, Levi, Francis, Lidereau, Rosette, Nogues, Catherine, Mira, Jean-Paul, Chompret, Agnès, Joulin, Virginie, Clavel-Chapelon, Françoise, Bourhis, Jean, André, Fabrice, Delaloge, Suzette, Tursz, Thomas, Kroemer, Guido, Zitvogel, Laurence

“…Conventional cancer treatments rely on radiotherapy and chemotherapy. Such treatments supposedly mediate their effects via the direct elimination of tumor…”
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Genetic and environmental factors in cutaneous malignant melanoma by Bressac-de-Paillerets, Brigitte, Avril, Marie-Françoise, Chompret, Agnès, Demenais, Florence

“…Cutaneous malignant melanoma (CMM) is an interesting example of multifactorial disease, where both genetic and environmental factors are involved and interact…”
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Pregnancies, Breast-Feeding, and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study (IBCCS) by Andrieu, Nadine, Goldgar, David E., Easton, Douglas F., Rookus, Matti, Brohet, Richard, Antoniou, Antonis C., Peock, Susan, Evans, Gareth, Eccles, Diana, Douglas, Fiona, Noguès, Catherine, Gauthier-Villars, Marion, Chompret, Agnès, Van Leeuwen, Flora E., Kluijt, Irma, Benitez, Javier, Arver, Brita, Olah, Edith, Chang-Claude, Jenny

“…Background: Multiparity, young age at first childbirth, and breast-feeding are associated with a reduced risk of breast cancer in the general population. The…”
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Geographical Variation in the Penetrance of CDKN2A Mutations for Melanoma by Bishop, D. Timothy, Demenais, Florence, Goldstein, Alisa M., Bergman, Wilma, Bishop, Julia Newton, Paillerets, Brigitte Bressac-de, Chompret, Agnès, Ghiorzo, Paola, Gruis, Nelleke, Hansson, Johan, Harland, Mark, Hayward, Nicholas, Holland, Elizabeth A., Mann, Graham J., Mantelli, Michela, Nancarrow, Derek, Platz, Anton, Tucker, Margaret A.

“…Background: Germline mutations in the CDKN2A gene, which encodes two proteins (p16INK4A and p14ARF), are the most common cause of inherited susceptibility to…”
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Oncogenetic consultation for breast cancer by Chompret, Agnès, Noguès, Catherine, Stoppa-Lyonnet, Dominique

“…Five percent of breast cancers are associated with a genetic predisposition, transmitted as an autosomal dominant trait of either maternal or paternal origin…”
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Patterns of familial aggregation of three melanoma risk factors: great number of naevi, light phototype and high degree of sun exposure by Briollais, Laurent, Chompret, Agnès, Guilloud-Bataille, Michel, Bressac-de Paillerets, Brigitte, Avril, Marie-Françoise, Demenais, Florence

“…Background Besides melanoma susceptibility genes and shared environmental exposures, part of the familial clustering of cutaneous malignant melanoma (CMM)…”
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Melanocortin-1 Receptor (MC1R) Gene Variants and Dysplastic Nevi Modify Penetrance of CDKN2A Mutations in French Melanoma-Prone Pedigrees by CHAUDRU, Valérie, LAUD, Karine, AVRIL, Marie-Francoise, MINIERE, Annie, CHOMPRET, Agnès, BRESSAC-DE PAILLERETS, Brigitte, DEMENAIS, Florence

“…Germline mutations in CDKN2A gene predispose to melanoma with high but incomplete penetrance. Penetrance of CDKN2A gene was found to be significantly…”
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Role of Radiation Dose in the Risk of Secondary Leukemia After a Solid Tumor in Childhood Treated Between 1980 and 1999 by Allard, Aurore, M.Sc, Haddy, Nadia, Ph.D, Le Deley, Marie-Cécile, M.D., Ph.D, Rubino, Carole, Lassalle, Mathilde, M.Sc, Samsaldin, Akthar, Ph.D, Quiniou, Eric, Ph.D, Chompret, Agnès, M.D, Lefkopoulos, Dimitri, Ph.D, Diallo, Ibrahima, de Vathaire, Florent, Ph.D

“…Purpose The purpose of this study was to estimate the risk of secondary leukemia as a function of radiation dose, taking into account heterogeneous radiation…”
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Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations by Brugières, Laurence, Pierron, Gaëlle, Chompret, Agnès, Paillerets, Brigitte Bressac-de, Di Rocco, Federico, Varlet, Pascale, Pierre-Kahn, Alain, Caron, Olivier, Grill, Jacques, Delattre, Olivier

“…Germline SUFU mutations were identified in two families with several children under 3 years of age diagnosed with medulloblastoma. All medulloblastomas in…”
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Significant contribution of germline BRCA2 rearrangements in male breast cancer families by TOURNIER, Isabelle, BRESSAC-DE PAILLERETS, Brigitte, LORTHOLARY, Alain, CHAPPUIS, Pierre, BOURDON, Violaine, BONADONA, Valérie, MAUGARD, Christine, GILBERT, Brigitte, NOGUES, Catherine, FREBOURG, Thierry, TOSI, Mario, SOBOL, Hagay, STOPPA-LYONNET, Dominique, LIDEREAU, Rosette, BARROIS, Michel, MAZOYER, Sylvie, COULET, Florence, HARDOUIN, Agnès, CHOMPRET, Agnès

“…Although screening for large deletions or duplications of the BRCA1 gene is becoming a routine component of the molecular diagnosis of familial breast cancer,…”
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Risk of Secondary Leukemia After a Solid Tumor in Childhood According to the Dose of Epipodophyllotoxins and Anthracyclines: A Case-Control Study by the Société Française d’Oncologie Pédiatrique by LE DELEY, Marie-Cécile, LEBLANC, Thierry, DE VATHAIRE, Florent, VASSAL, Gilles, HILL, Catherine, SHAMSALDIN, Akthar, RAQUIN, Marie-Anne, LACOUR, Brigitte, SOMMELET, Danièle, CHOMPRET, Agnès, CAYUELA, Jean-Michel, BAYLE, Chantal, BERNHEIM, Alain

“…To estimate the risk of secondary leukemia as a function of the dose of epipodophyllotoxins and anthracyclines. We conducted a case-control study of the risk…”
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Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD by PASINI, Barbara, MCWHINNEY, Sarah R, BAUDIN, Eric, CHOMPRET, Agnes, ELLISON, Jay W, BRIERE, Jean-Jacques, RUSTIN, Pierre, GIMENEZ-ROQUEPLO, Anne-Paule, CHARIS ENG, AIDAN CARNEY, J, STRATAKIS, Constantine A, BEI, Thalia, MATYAKHINA, Ludmila, STERGIOPOULOS, Sotirios, MUCHOW, Michael, BOIKOS, Sosipatros A, FERRANDO, Barbara, PACAK, Karel, ASSIE, Guillaume

“…Gastrointestinal stromal tumors (GISTs) may be caused by germline mutations of the KIT and platelet-derived growth factor receptor-alpha (PDGFRA) genes and…”
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Influence of Genes, Nevi, and Sun Sensitivity on Melanoma Risk in a Family Sample Unselected by Family History and in Melanoma-Prone Families by Chaudru, Valérie, Chompret, Agnès, Bressac-de Paillerets, Brigitte, Spatz, Alain, Avril, Marie-Françoise, Demenais, Florence

“…Background: Few family studies have investigated the effects of genetic, environmental, and host factors on melanoma risk, and most have been restricted to…”
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Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients by Kannengiesser, Caroline, Brookes, Sharon, del Arroyo, Anna Gutierrez, Pham, Danielle, Bombled, Johny, Barrois, Michel, Mauffret, Olivier, Avril M, Marie-Françoise, Chompret, Agnès, Lenoir, Gilbert M, Sarasin, Alain, Peters, Gordon, Paillerets, Brigitte Bressac-de

“…Germline mutations of the CDKN2A gene are found in melanoma-prone families and individuals with multiple sporadic melanomas. The encoded protein, p16INK⁴A,…”
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Screening for TP53 rearrangements in families with the Li-Fraumeni syndrome reveals a complete deletion of the TP53 gene by BOUGEARD, Gaëlle, BRUGIERES, Laurence, FREBOURG, Thierry, CHOMPRET, Agnès, GESTA, Paul, CHARBONNIER, Francoise, VALENT, Alexander, MARTIN, Cosette, RAUX, Grégory, FEUNTEUN, Jean, BRESSAC-DE PAILLERETS, Brigitte

“…The absence of detectable germline TP53 mutations in a fraction of families with Li-Fraumeni syndrome (LFS) has suggested the involvement of other genes, but…”
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Patients’ characteristics and rate of Internet use to obtain cancer information by Mancini, Julien, Noguès, Catherine, Adenis, Claude, Berthet, Pascaline, Bonadona, Valérie, Chompret, Agnès, Coupier, Isabelle, Eisinger, François, Fricker, Jean-Pierre, Gauthier-Villars, Marion, Lasset, Christine, Lortholary, Alain, N’Guyen, Tan Dat, Vennin, Philippe, Sobol, Hagay, Stoppa-Lyonnet, Dominique, Julian-Reynier, Claire

“…The aim of this study was to present baseline data on the access to Internet by French breast cancer patients attending genetic clinics and to examine factors…”
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Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors by Linger, Rachel, Dudakia, Darshna, Huddart, Robert, Tucker, Kathy, Friedlander, Michael, Phillips, Kelly-Anne, Hogg, David, Jewett, Michael A. S., Lohynska, Radka, Daugaard, Gedske, Richard, Stéphane, Chompret, Agnes, Stoppa-Lyonnet, Dominique, Bonaïti-Pellié, Catherine, Heidenreich, Axel, Albers, Peter, Olah, Edith, Geczi, Lajos, Bodrogi, Istvan, Daly, Peter A., Guilford, Parry, Fosså, Sophie D., Heimdal, Ketil, Tjulandin, Sergei A., Liubchenko, Ludmila, Stoll, Hans, Weber, Walter, Einhorn, Lawrence, McMaster, Mary, Korde, Larissa, Greene, Mark H., Nathanson, Katherine L., Cortessis, Victoria, Easton, Douglas F., Bishop, D. Timothy, Stratton, Michael R., Rapley, Elizabeth A.

“…A base substitution in the mouse Dnd1 gene resulting in a truncated Dnd protein has been shown to be responsible for germ cell loss and the development of…”
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Impact of an information booklet on satisfaction and decision-making about BRCA genetic testing by Mancini, Julien, Noguès, Catherine, Adenis, Claude, Berthet, Pascaline, Bonadona, Valerie, Chompret, Agnès, Coupier, Isabelle, Eisinger, François, Fricker, Jean-Pierre, Gauthier-Villars, Marion, Lasset, Christine, Lortholary, Alain, N’Guyen, Tan Dat, Vennin, Philippe, Sobol, Hagay, Stoppa-Lyonnet, Dominique, Julian-Reynier, Claire

“…The aim of this study was to assess the impact of a standardized patient information booklet on decisions women make about genetic testing. This French…”
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Radiation and genetic factors in the risk of second malignant neoplasms after a first cancer in childhood by Kony, S J, de Vathaire, F, Chompret, A, Shamsaldim, A, Grimaud, E, Raquin, M A, Oberlin, O, Brugières, L, Feunteun, J, Eschwège, F, Chavaudra, J, Lemerle, J, Bonaïti-Pellié, C

“…Radiotherapy and chemotherapy are associated with an increased risk of second malignant neoplasm (SMN). An association between SMN and familial aggregation has…”
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