Search Results - "Chomic, Robert"
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Adrenal-derived 11-oxygenated 19-carbon steroids are the dominant androgens in classic 21-hydroxylase deficiency
Published in European journal of endocrinology (01-05-2016)“…Abstract Objective To comprehensively characterize androgens and androgen precursors in classic 21-hydroxylase deficiency (21OHD) and to gain insights into the…”
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Profiles of 21-Carbon Steroids in 21-hydroxylase Deficiency
Published in The journal of clinical endocrinology and metabolism (01-06-2015)“…Context: Marked elevations of 17-hydroxyprogesterone (17OHP) are characteristic of classic 21-hydroxylase deficiency (21OHD). Testing of 17OHP provides the…”
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Journal Article -
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Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-04-2016)“…Androgen and estrogen biosynthesis in mammals requires the 17,20-lyase activity of cytochrome P450 17A1 (steroid 17-hydroxylase/17,20-lyase). Maximal…”
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Serum Cortisol-to-Cortisone Ratio and Blood Pressure in Severe Obesity before and after Weight Loss
Published in Cardiorenal medicine (01-12-2015)“…Background/Aims: The pathogenesis of obesity-associated hypertension is poorly understood. Serum cortisol-to-cortisone ratio (F/E ratio) is a marker of…”
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