Search Results - "Choma, Michael A"

Low spatial coherence electrically pumped semiconductor laser for speckle-free full-field imaging by Redding, Brandon, Cerjan, Alexander, Huang, Xue, Lee, Minjoo Larry, Stone, A. Douglas, Choma, Michael A., Cao, Hui

“…The spatial coherence of laser sources has limited their application to parallel imaging and projection due to coherent artifacts, such as speckle. In…”
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Full-field interferometric confocal microscopy using a VCSEL array by Redding, Brandon, Bromberg, Yaron, Choma, Michael A, Cao, Hui

“…We present an interferometric confocal microscope using an array of 1200 vertical cavity surface emitting lasers (VCSELs) coupled to a multimode fiber. Spatial…”
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Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation by Yuan, Shiaulou, Li, Jade, Diener, Dennis R, Choma, Michael A, Rosenbaum, Joel L, Sun, Zhaoxia

“…The cilium serves as a cellular antenna by coordinating upstream environmental cues with numerous downstream signaling processes that are indispensable for the…”
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Resolving directional ambiguity in dynamic light scattering-based transverse motion velocimetry in optical coherence tomography by Huang, Brendan K, Choma, Michael A

“…Dynamic light scattering-based optical coherence tomography approaches have been successfully implemented to measure total transverse (xy) flow speed, but are…”
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Bias in medical AI: Implications for clinical decision-making by Cross, James L., Choma, Michael A., Onofrey, John A.

“…Biases in medical artificial intelligence (AI) arise and compound throughout the AI lifecycle. These biases can have significant clinical consequences,…”
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Speckle-free laser imaging using random laser illumination by Redding, Brandon, Choma, Michael A., Cao, Hui

“…Many imaging applications require increasingly bright illumination sources, motivating the replacement of conventional thermal light sources with bright…”
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Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies by Deniz, Engin, Jonas, Stephan, Khokha, Mustafa K., Choma, Michael A.

“…Congenital heart disease (CHD) is a significant cause of mortality in infants and adults. Currently human genomic analysis has identified a number of candidate…”
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Drosophila as a model for the identification of genes causing adult human heart disease by Wolf, M.J, Amrein, H, Izatt, J.A, Choma, M.A, Reedy, M.C, Rockman, H.A

“…Drosophila melanogaster genetics provides the advantage of molecularly defined P-element insertions and deletions that span the entire genome. Although…”
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Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source by Choma, Michael A, Hsu, Kevin, Izatt, Joseph A

“…The increased sensitivity of spectral domain optical coherence tomography (OCT) has driven the development of a new generation of technologies in OCT,…”
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Microfluidic characterization of cilia-driven fluid flow using optical coherence tomography-based particle tracking velocimetry by Jonas, Stephan, Bhattacharya, Dipankan, Khokha, Mustafa K, Choma, Michael A

“…Motile cilia are cellular organelles that generate directional fluid flow across various epithelial surfaces including the embryonic node and respiratory…”
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Particle streak velocimetry-optical coherence tomography: a novel method for multidimensional imaging of microscale fluid flows by Zhou, Kevin C, Huang, Brendan K, Gamm, Ute A, Bhandari, Vineet, Khokha, Mustafa K, Choma, Michael A

“…We present a new OCT method for flow speed quantification and directional velocimetry: particle streak velocimetry-OCT (PSV-OCT). PSV-OCT generates…”
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Physiological homology between Drosophila melanogaster and vertebrate cardiovascular systems by Choma, Michael A, Suter, Melissa J, Vakoc, Benjamin J, Bouma, Brett E, Tearney, Guillermo J

“…The physiology of the Drosophila melanogaster cardiovascular system remains poorly characterized compared with its vertebrate counterparts. Basic measures of…”
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Low-spatial-coherence high-radiance broadband fiber source for speckle free imaging by Redding, Brandon, Ahmadi, Peyman, Mokan, Vadim, Seifert, Martin, Choma, Michael A, Cao, Hui

“…We design and demonstrate a fiber-based amplified spontaneous emission (ASE) source with low spatial coherence, low temporal coherence, and high power per…”
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Spatial coherence of random laser emission by Redding, Brandon, Choma, Michael A, Cao, Hui

“…We experimentally studied the spatial coherence of random laser emission from dye solutions containing nanoparticles. The spatial coherence, measured in a…”
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Multi-modal and multiscale imaging approaches reveal novel cardiovascular pathophysiology in Drosophila melanogaster by Weismann, Constance G, Blice-Baum, Anna, Tong, Tangji, Li, Joyce, Huang, Brendan K, Jonas, Stephan M, Cammarato, Anthony, Choma, Michael A

“…Establishing connections between changes in linear DNA sequences and complex downstream mesoscopic pathology remains a major challenge in biology. Herein, we…”
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Microscale imaging of cilia-driven fluid flow by Huang, Brendan K, Choma, Michael A

“…Cilia-driven fluid flow is important for multiple processes in the body, including respiratory mucus clearance, gamete transport in the oviduct, right–left…”
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High-speed line-field confocal holographic microscope for quantitative phase imaging by Liu, Changgeng, Knitter, Sebastian, Cong, Zhilong, Sencan, Ikbal, Cao, Hui, Choma, Michael A

“…We present a high-speed and phase-sensitive reflectance line-scanning confocal holographic microscope (LCHM). We achieved rapid confocal imaging using a fast…”
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Noise analysis of spectrometers based on speckle pattern reconstruction by Redding, Brandon, Popoff, Sebastien M, Bromberg, Yaron, Choma, Michael A, Cao, Hui

“…Speckle patterns produced by a disordered medium or a multimode fiber can be used as a fingerprint to uniquely identify the input light frequency…”
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Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography by Deniz, Engin, Jonas, Stephan, Hooper, Michael, N. Griffin, John, Choma, Michael A., Khokha, Mustafa K.

“…Birth defects affect 3% of children in the United States. Among the birth defects, congenital heart disease and craniofacial malformations are major causes of…”
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Speckle-free laser imaging using random laser illumination by Redding, Brandon, Choma, Michael A, Cao, Hui

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