Search Results - "Cholanians, Aram B"
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Modulating NRF2 in Disease: Timing Is Everything
Published in Annual review of pharmacology and toxicology (06-01-2019)“…The transcription factor nuclear factor erythroid 2 (NF-E2)-related factor 2 (NRF2) is a central regulator of redox, metabolic, and protein homeostasis that…”
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2
The Rodent Forced Swim Test Measures Stress-Coping Strategy, Not Depression-like Behavior
Published in ACS chemical neuroscience (17-05-2017)“…The forced swim test (FST) measures coping strategy to an acute inescapable stress and thus provides unique insight into the neural limb of the stress…”
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Increased O-GlcNAcylation of SNAP29 Drives Arsenic-Induced Autophagic Dysfunction
Published in Molecular and cellular biology (01-06-2018)“…Environmental exposure to arsenic is linked to adverse health effects, including cancer and diabetes. Pleiotropic cellular effects are observed with arsenic…”
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Concurrent Inhibition of Vesicular Monoamine Transporter 2 Does Not Protect Against 3,4-Methylenedioxymethamphetamine (Ecstasy) Induced Neurotoxicity
Published in Toxicological sciences (01-07-2019)“…Abstract 3, 4-Methylenedioxymethamphetamine (MDMA) is a hallucinogenic amphetamine derivative. The acute effects of MDMA are hyperthermia, hyperactivity, and…”
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Glial cell response to 3,4-(+/-)-methylenedioxymethamphetamine and its metabolites
Published in Toxicological sciences (01-03-2014)“…3,4-(±)-Methylenedioxymethamphetamine (MDMA) and 3,4-(±)-methylenedioxyamphetamine (MDA), a primary metabolite of MDMA, are phenylethylamine derivatives that…”
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Vesicular monoamine transporter 2 and the acute and long-term response to 3,4-(±)-methylenedioxymethamphetamine
Published in Toxicological sciences (01-01-2015)“…3,4-(±)-Methylenedioxymethamphetamine (MDMA, Ecstasy) is a ring-substituted amphetamine derivative with potent psychostimulant properties. The…”
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From the Cover: Arsenic Induces Accumulation of α-Synuclein: Implications for Synucleinopathies and Neurodegeneration
Published in Toxicological sciences (01-10-2016)“…Synucleinopathies, including Parkinson's disease (PD), are neurodegenerative diseases characterized by accumulation of α-synuclein (SYN), a small neuronal…”
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Serotonin reuptake transporter deficiency modulates the acute thermoregulatory and locomotor activity response to 3,4-(±)-methylenedioxymethamphetamine, and attenuates depletions in serotonin levels in SERT-KO rats
Published in Toxicological sciences (01-06-2014)“…3,4-(±)-Methylenedioxymethamphetamine (MDMA) is a ring-substituted amphetamine derivative with potent psychostimulant properties. The neuropharmacological…”
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9
Catechol-O-Methyltransferase and 3,4-(±)-Methylenedioxymethamphetamine Toxicity
Published in Toxicological sciences (01-05-2014)“…Editor's Highlight: Ecstasy, Molly, Mandy, X. The street names for methylenedioxymethamphetamine (MDMA), as well as its euphoric properties, are well known to…”
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Abstract 6631: Association between poliovirus receptor (PVR) expression in tumor and exclusion of immune cells expressing T cell immunoreceptor with Ig and ITIM domain (TIGIT) from tumor area
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Context: TIGIT has grown to be an increasingly important target for immunotherapy of cancer. However, it is unclear if there is an association between…”
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Dopamine induced post-translational modifications of alpha-synuclein and the role of arsenic in the development of Parkinson's disease and other synucleinopathies
Published 01-01-2016“…Synucleinopathies are a family of neurodegenerative diseases, with the distinctive pathological feature of Lewy bodies, which include Parkinson’s disease. Lewy…”
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