Search Results - "Choi, Younho"

Autophagy during viral infection — a double-edged sword by Choi, Younho, Bowman, James W., Jung, Jae U.

“…Autophagy is a powerful tool that host cells use to defend against viral infection. Double-membrane vesicles, termed autophagosomes, deliver trapped viral…”
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SERPINB1-mediated checkpoint of inflammatory caspase activation by Choi, Youn Jung, Kim, Stephanie, Choi, Younho, Nielsen, Travis B., Yan, Jun, Lu, Alvin, Ruan, Jianbin, Lee, Hye-Ra, Wu, Hao, Spellberg, Brad, Jung, Jae U.

“…Inflammatory caspases (caspase-1, caspase-4, caspase-5 and caspase-11 (caspase-1/-4/-5/-11)) mediate host defense against microbial infections, processing…”
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Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets by Kim, Young-Il, Yu, Kwang-Min, Koh, June-Young, Kim, Eun-Ha, Kim, Se-Mi, Kim, Eun Ji, Casel, Mark Anthony B., Rollon, Rare, Jang, Seung-Gyu, Song, Min-Suk, Park, Su-Jin, Jeong, Hye Won, Kim, Eung-Gook, Lee, Ok-Jun, Kim, Yong-Dae, Choi, Younho, Lee, Shin-Ae, Choi, Youn Jung, Park, Su-Hyung, Jung, Jae U., Choi, Young Ki

“…While the seroprevalence of SARS-CoV-2 in healthy people does not differ significantly among age groups, those aged 65 years or older exhibit strikingly higher…”
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Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets by Park, Su-Jin, Yu, Kwang-Min, Kim, Young-Il, Kim, Se-Mi, Kim, Eun-Ha, Kim, Seong-Gyu, Kim, Eun Ji, Casel, Mark Anthony B, Rollon, Rare, Jang, Seung-Gyu, Lee, Min-Hyeok, Chang, Jae-Hyung, Song, Min-Suk, Jeong, Hye Won, Choi, Younho, Chen, Weiqiang, Shin, Woo-Jin, Jung, Jae U, Choi, Young Ki

“…Due to the urgent need of a therapeutic treatment for coronavirus (CoV) disease 2019 (COVID-19) patients, a number of FDA-approved/repurposed drugs have been…”
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Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway by Seo, Gil Ju, Yang, Aerin, Tan, Brandon, Kim, Sungyoon, Liang, Qiming, Choi, Younho, Yuan, Weiming, Feng, Pinghui, Park, Hee-Sung, Jung, Jae U.

“…Upon DNA stimulation, cyclic GMP-AMP synthase (cGAS) synthesizes the second messenger cyclic GMP-AMP (cGAMP) that binds to the STING, triggering antiviral…”
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Identification and Characterization of a Novel Flagellum-Dependent Salmonella-Infecting Bacteriophage, iEPS5 by Choi, Younho, Shin, Hakdong, Lee, Ju-Hoon, Ryu, Sangryeol

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Receptor diversity and host interaction of bacteriophages infecting Salmonella enterica serovar Typhimurium by Shin, Hakdong, Lee, Ju-Hoon, Kim, Hyeryen, Choi, Younho, Heu, Sunggi, Ryu, Sangryeol

“…Salmonella enterica subspecies enterica serovar Typhimurium is a gram-negative pathogen causing salmonellosis. Salmonella Typhimurium-targeting bacteriophages…”
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TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice by Zeng, Jianxiong, Wang, Yaoming, Luo, Zhifei, Chang, Lin-Chun, Yoo, Ji Seung, Yan, Huan, Choi, Younho, Xie, Xiaochun, Deverman, Benjamin E., Gradinaru, Viviana, Gupton, Stephanie L., Zlokovic, Berislav V., Zhao, Zhen, Jung, Jae U.

“…Excessive and unresolved neuroinflammation is a key component of the pathological cascade in brain injuries such as ischemic stroke. Here, we report that…”
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Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie bandavirus in aged ferrets by Kim, Dokyun, Kim, Eunha, Kim, Semi, Chung, Youseung, Lai, Chih-Jen, Cha, Inho, Cho, Sung-Dong, Choi, Yunseo, Dai, Xinghong, Kim, Stephanie, Kang, Seokmin, Kwak, Mi-Jeong, Liu, Ziyi, Choi, Younho, Park, Su-Hyung, Choi, Young Ki, Jung, Jae U

“…(DBV) is an emerging tick-borne virus that causes severe fever with thrombocytopenia syndrome (SFTS) in infected patients. Human SFTS symptoms progress from…”
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Molecular Signatures of Inflammatory Profile and B-Cell Function in Patients with Severe Fever with Thrombocytopenia Syndrome by Park, Angela, Park, Su-Jin, Jung, Kyle L, Kim, Se Mi, Kim, Eun-Ha, Kim, Young-Il, Foo, Suan-Sin, Kim, Sunghyun, Kim, Seong-Gyu, Yu, Kwang-Min, Choi, Younho, Kim, Ji Yeun, Baek, Yun Hee, Song, Min-Suk, Kim, Seung Ryul, Kim, Seok-Yong, Jeong, Hye Won, Kim, Sung-Han, Jung, Jae U, Choi, Young Ki

“…Dabie bandavirus (severe fever with thrombocytopenia syndrome virus [SFTSV]) induces an immunopathogenic disease with a high fatality rate; however, the…”
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Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation by Choi, Youn Jung, Yoo, Ji-Seung, Jung, Kyle, Rice, Logan, Kim, Dokyun, Zlojutro, Violetta, Frimel, Matthew, Madden, Evan, Choi, Un Yung, Foo, Suan-Sin, Choi, Younho, Jiang, Zhongyi, Johnson, Holly, Kwak, Mi-Jeong, Kang, Seokmin, Hong, Brian, Seo, Gil Ju, Kim, Stephanie, Lee, Shin-Ae, Amini-Bavil-Olyaee, Samad, Maazi, Hadi, Akbari, Omid, Asosingh, Kewal, Jung, Jae U.

“…Lung mast cells are important in host defense, and excessive proliferation or activation of these cells can cause chronic inflammatory disorders like asthma…”
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Plasmid-encoded MCP is involved in virulence, motility, and biofilm formation of Cronobacter sakazakii ATCC 29544 by Choi, Younho, Kim, Seongok, Hwang, Hyelyeon, Kim, Kwang-Pyo, Kang, Dong-Hyun, Ryu, Sangryeol

“…The aim of this study was to elucidate the function of the plasmid-borne mcp (methyl-accepting chemotaxis protein) gene, which plays pleiotropic roles in…”
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TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice by Zeng, Jianxiong, Wang, Yaoming, Luo, Zhifei, Chang, Lin-Chun, Yoo, Ji Seung, Yan, Huan, Choi, Younho, Xie, Xiaochun, Deverman, Benjamin E., Gradinaru, Viviana, Gupton, Stephanie L., Zlokovic, Berislav V., Zhao, Zhen, Jung, Jae U.

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The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target by Wang, Wenjie, Shin, Woo-Jin, Zhang, Bojie, Choi, Younho, Yoo, Ji-Seung, Zimmerman, Maxwell I., Frederick, Thomas E., Bowman, Gregory R., Gross, Michael L., Leung, Daisy W., Jung, Jae U., Amarasinghe, Gaya K.

“…Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%–30% case mortality rates and is related to the Heartland virus (HRTV)…”
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Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation by Choi, Youn Jung, Kim, Stephanie, Choi, Younho, Nielsen, Travis B., Yan, Jun, Lu, Alvin, Ruan, Jianbin, Lee, Hye-Ra, Wu, Hao, Spellberg, Brad, Jung, Jae U.

“…In the version of this article initially published, the label (CASP4-C 285 A-HA) above the second and fifth lanes in the right blot in Fig. 1e is incorrect;…”
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Expression of STM4467-Encoded Arginine Deiminase Controlled by the STM4463 Regulator Contributes to Salmonella enterica Serovar Typhimurium Virulence by CHOI, Younho, CHOI, Jeongjoon, GROISMAN, Eduardo A, KANG, Dong-Hyun, SHIN, Dongwoo, RYU, Sangryeol

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Complete Genome Sequence of Cronobacter sakazakii Temperate Bacteriophage phiES15 by LEE, Ju-Hoon, CHOI, Younho, SHIN, Hakdong, LEE, Junghyun, RYU, Sangryeol

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Complete Genome Sequence of the Opportunistic Food-Borne Pathogen Cronobacter sakazakii ES15 by Shin, Hakdong, Lee, Ju-Hoon, Choi, Younho, Ryu, Sangryeol

“…Cronobacter sakazakii is an emerging pathogen associated with several outbreaks of food-borne illness in premature infants. To characterize its physiology and…”
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Severe Fever with Thrombocytopenia Syndrome Virus NSs Interacts with TRIM21 To Activate the p62-Keap1-Nrf2 Pathway by Choi, Younho, Jiang, Zhongyi, Shin, Woo-Jin, Jung, Jae U

“…Nuclear factor erythroid 2-related factor 2 (Nrf2) dissociates from its inhibitor, Keap1, upon stress signals and subsequently induces an antioxidant response…”
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SFTSV Gn‐Head mRNA vaccine confers efficient protection against lethal viral challenge by Kim, Dokyun, Lai, Chih‐Jen, Cha, Inho, Kang, Seokmin, Yang, Wan‐Shan, Choi, Younho, Jung, Jae U.

“…Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick‐borne virus, causing thrombocytopenia and hemorrhagic fever, with a fatality rate…”
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