Search Results - "Choi, Wonjae E."
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The Vacuum Assisted Negative Pressure Isolation Hood (VANISH) System: Novel Application of the Stryker Neptune™ Suction Machine to Create COVID-19 Negative Pressure Isolation Environments
Published in Curēus (Palo Alto, CA) (14-05-2020)“…Coronavirus disease 2019 (COVID-19) may remain viable in the air for up to three hours, placing health care workers in close proximity to aerosolizing…”
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Structural Asymmetry and Half-Site Reactivity in the T to R Allosteric Transition of the Insulin Hexamer
Published in Biochemistry (Easton) (08-11-1994)“…The zinc-insulin hexamer, the storage form of insulin in the pancreas, is an allosteric protein capable of undergoing transitions between three distinct…”
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Carboxylate Ions Are Strong Allosteric Ligands for the HisB10 Sites of the R-State Insulin Hexamer
Published in Biochemistry (Easton) (12-08-1997)“…The insulin hexamer is an allosteric protein which displays positive and negative cooperativity and half-site reactivity that is modulated by strong homotropic…”
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Specificity of the PTB Domain of Shc for β Turn-forming Pentapeptide Motifs Amino-terminal to Phosphotyrosine
Published in The Journal of biological chemistry (04-08-1995)“…Shc phosphorylation in cells following growth factor, insulin, cytokine, and lymphocyte receptor activation leads to its association with Grb2 and activation…”
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Ligand Binding to Wild-type and E-B13Q Mutant Insulins: A Three-state Allosteric Model System Showing Half-site Reactivity
Published in Journal of molecular biology (27-01-1995)“…By using ultra-violet and visible absorbance in conjunction with high field 1H-nuclear magnetic resonance spectroscopy, the insulin hexamer has been shown to…”
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Allosteric transition of the insulin hexamer is modulated by homotropic and heterotropic interactions
Published in Biochemistry (Easton) (02-11-1993)“…The allosteric behavior of the Co(II)-substituted insulin hexamer has been investigated using electronic spectroscopy to study the binding of different…”
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Spectroscopic evidence for preexisting T- and R-state insulin hexamer conformations
Published in Proteins, structure, function, and bioinformatics (01-12-1996)“…The insulin hexamer is an allosteric protein exhibiting both positive and negative cooperative homotropic interactions and positive cooperative heterotropic…”
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Specificity of the PTB Domain of Shc for Turn-forming Pentapeptide Motifs Amino-terminal to Phosphotyrosine
Published in The Journal of biological chemistry (04-08-1995)“…Shc phosphorylation in cells following growth factor, insulin, cytokine, and lymphocyte receptor activation leads to its association with Grb2 and activation…”
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Journal Article