Search Results - "Choi, Song Hyen"

Effects of DA-9801 on the inflammation and apoptosis induced by angiotensin II in human dermal microvascular endothelial cells by Hong, Oak-Kee, Lee, Seong-Su, Yoo, Soon Jib, Choi, Song-Hyen, Lee, Min-Kyung, Cha, Bong-Yun, Kim, Mee-Kyoung, Baek, Ki-Hyun, Song, Ki-Ho, Kwon, Hyuk-Sang

“…DA-9801, a plant-based drug used for the treatment of diabetic neuropathy, is known to improve angiotensin II (Ang II)-induced vascular endothelial cell…”
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Novel botanical drug DA-9803 prevents deficits in Alzheimer's mouse models by Pagnier, Guillaume J, Kastanenka, Ksenia V, Sohn, Miwon, Choi, Sangzin, Choi, Song-Hyen, Soh, HyeYeon, Bacskai, Brian J

“…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by deposition of amyloid plaques and disruption of neural circuitry, leading to…”
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New reliable scoring system, Toyama mouse score, to evaluate locomotor function following spinal cord injury in mice by Shigyo, Michiko, Tanabe, Norio, Kuboyama, Tomoharu, Choi, Song-Hyen, Tohda, Chihiro

“…Among the variety of methods used to evaluate locomotor function following a spinal cord injury (SCI), the Basso Mouse Scale score (BMS) has been widely used…”
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The complete mitochondrial genome of Wolfiporia cocos (Polypolales: Polyporaceae) by Lee, Sae Hyun, Lee, Hyun-Oh, Park, Hyun-Seung, Ryu, Hyun Joon, Kim, Jung Woo, Choi, Song-Hyen, Park, Jee Young, Yang, Tae-Jin

“…Wolfiporia cocos have been used as diuretic, sedative, and tonic medicine. Although its medicinal effects were reported, its genomic information is rare. In…”
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PAR-1622 is a selective peroxisome proliferator-activated receptor γ partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention by Kim, Mi-Kyung, Chae, Yu Na, Kim, Hae Sun, Choi, Song-hyen, Son, Moon Ho, Kim, Soon Hoe, Kim, Jin Kwan, Moon, Ho Sang, Park, Sang Kuk, Shin, Young Ah, Kim, Jae Gyu, Lee, Chun Ho, Lim, Joong In, Shin, Chang Yell

“…Peroxisome proliferator-activated receptor (PPAR) γ is known to be a key regulator of insulin resistance. PAR-1622 is a novel small molecule compound…”
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Prevention and treatment effect of evogliptin on hepatic steatosis in high-fat-fed animal models by Kim, Mi-Kyung, Chae, Yu Na, Ahn, Gook-Jun, Shin, Chang Yell, Choi, Song-hyen, Yang, Eun Kyoung, Sohn, Yong Sung, Son, Moon-Ho

“…Dipeptidyl peptidase 4 (DPP4) is an adipokine that interrupts insulin signaling. The resulting insulin resistance exacerbates hepatic steatosis. We previously…”
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DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes by Kim, Mi-Kyung, Chae, Yu Na, Kim, Ha Dong, Yang, Eun Kyoung, Cho, Eun Jung, Choi, Song-hyen, Cheong, Ye-Hwang, Kim, Hae-Sun, Kim, Heung Jae, Jo, Yeong Woo, Son, Moon-Ho, Kim, Soon-Hoe, Shin, Chang Yell

“…To characterize the pharmacodynamic profile of DA-1229, a novel dipeptidyl peptidase (DPP) 4 inhibitor. Enzyme inhibition assays against DPP4, DPP8 and DPP9…”
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A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesis by Cho, Jae Min, Jang, Hye Won, Cheon, Hwanju, Jeong, Yeon Taek, Kim, Do-Hoon, Lim, Yu-Mi, Choi, Song-hyen, Yang, Eun-kyoung, Shin, Chang-Yell, Son, Moon Ho, Kim, Soon Hoe, Kim, Heung-Jae, Lee, Myung-Shik

“…Abstract We studied the effect of a novel dipeptidyl peptidase IV (DPP IV) inhibitor, DA-1229, on blood glucose profile and pancreatic β-cell mass in…”
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Discovery of DA-1229: A potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes by Kim, Heung Jae, Kwak, Woo Young, Min, Jong Pil, Lee, Jae Young, Yoon, Tae Hyun, Kim, Ha Dong, Shin, Chang Yell, Kim, Mi Kyung, Choi, Song Hyen, Kim, Hae Sun, Yang, Eun Kyoung, Cheong, Ye Hwang, Chae, Yu Na, Park, Kyung Jin, Jang, Ji Myun, Choi, Soo Jung, Son, Moon Ho, Kim, Soon Hoe, Yoo, Moohi, Lee, Bong Jin

“…The synthesis and SAR studies of β-amino amide DPP-4 inhibitor 5f are reported. A series of β-amino amide containing substituted piperazine-2-one derivatives…”
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Stress-induced decrease of granule cell proliferation in adult rat hippocampus: assessment of granule cell proliferation using high doses of bromodeoxyuridine before and after restraint stress by Kim, Sung-Jin, Lee, Keum-Ju, Shin, You-Chan, Choi, Song-Hyen, Do, Eunju, Kim, Sangduk, Chun, Boe-Gwun, Lee, Min-Soo, Shin, Kyung-Ho

“…Stress is known to inhibit granule cell proliferation in the hippocampus. However, recent studies suggest that the commonly used dose of bromodeoxyuridine…”
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PAM-1616, a selective peroxisome proliferator-activated receptor γ modulator with preserved anti-diabetic efficacy and reduced adverse effects by Kim, Mi-Kyung, Chae, Yu Na, Choi, Song-hyen, Moon, Ho Sang, Son, Moon-Ho, Bae, Myung-Ho, Choi, Hyun-ho, Hur, Youn, Kim, Eunkyung, Park, Yoo Hoi, Park, Chan Sun, Kim, Jae Gyu, Lim, Joong In, Shin, Chang Yell

“…Peroxisome proliferator-activated receptor (PPAR) γ is known to be a key regulator of insulin resistance. PAM-1616 is a novel, non-thiazolidinedione small…”
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Chronic mild stress decreases survival, but not proliferation, of new-born cells in adult rat hippocampus by Lee, Kuem-Ju, Kim, Sung-Jin, Kim, Suk-Won, Choi, Song-Hyen, Shin, You-Chan, Park, Sang-Ha, Moon, Bo-Hyun, Cho, Eujin, Lee, Min-Soo, Choi, Sang-Hyun, Chun, Boe-Gwun, Shin, Kyung-Ho

“…New-born cells continue to proliferate and survive to become mature granule cells in adult rat hippocampus. Although this process, known as neurogenesis, is…”
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Effects of repeated tianeptine treatment on CRF mRNA expression in non-stressed and chronic mild stress-exposed rats by Kim, Sung-Jin, Park, Sang-Ha, Choi, Song-hyen, Moon, Bo-Hyun, Lee, Kuem-Ju, Kang, Seung Woo, Lee, Min-Soo, Choi, Sang-Hyun, Chun, Boe-Gwun, Shin, Kyung-Ho

“…Accumulating evidence suggests that dysregulation of corticotropin-releasing factor (CRF) may play a role in depression and that this dysregulation may be…”
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Lamotrigine prevents MK801-induced alterations in early growth response factor-1 mRNA levels and immunoreactivity in the rat brain by Park, Sang-Ha, Seo, Young Ho, Moon, Bo-Hyun, Choi, Song-hyen, Kang, Seungwoo, Lee, Kuem-Ju, Choi, Sang-Hyun, Lee, Min-Soo, Chun, Boe-Gwun, Shin, Kyung-Ho

“…MK801 (dizocilpine) induces selective neurotoxic effects in the retrosplenial cortex, ranging from neuronal vacuolization to irreversible neurodegeneration…”
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Effects of Repeated Citalopram Treatments on Chronic Mild Stress- Induced Growth Associated Protein-43 mRNA Expression in Rat Hippocampus by Park, Sang-Ha, Choi, Song-Hyen, Lee, Ji-Min, Kang, Seung-Woo, Shin, You-Chan, Kim, Hyun-Ju, Kim, Hyun-Jung, Shin, Seung-Keon, Lee, Min-Soo, Shin, Kyung-Ho

“…Although growth associated protein-43 (GAP-43) is known to playa significant role in the regulation of axonal growth and the formation of new neuronal…”
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Doxapram increases corticotropin-releasing factor immunoreactivity and mRNA expression in the rat central nucleus of the amygdala by Choi, Song-hyen, Kim, Sung-Jin, Park, Sang-Ha, Moon, Bo-Hyun, Do, Eunju, Chun, Boe-Gwun, Lee, Min-Soo, Shin, Kyung-Ho

“…Doxapram causes panic anxiety in humans. To determine whether doxapram alters corticotropin-releasing factor (CRF) expression in the central nucleus of the…”
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Effects of Repeated Citalopram Treatments on Chronic Mild Stress-Induced Growth Associated Protein-43 mRNA Expression in Rat Hippocampus by Park, Sang-Ha, Choi, Song-hyen, Lee, Jimin, Kang, Seungwoo, Shin, You-Chan, Kim, Hyun-Ju, Kim, Hyun Jung, Shin, Seung Keon, Lee, Min-Soo, Shin, Kyung-Ho

“…Although growth associated protein-43 (GAP-43) is known to play a significant role in the regulation of axonal growth and the formation of new neuronal…”
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