Search Results - "Choi, Philip Y"
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Australian and New Zealand approach to diagnosis and management of vaccine‐induced immune thrombosis and thrombocytopenia
Published in Medical journal of Australia (20-09-2021)Get full text
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Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
Published in The New England journal of medicine (15-07-2021)“…To the Editor: Greinacher et al. (April 9) 1 report on the development of platelet-activating antibodies against platelet factor 4 (PF4) after ChAdOx1 nCoV-19…”
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Platelets mediate the clearance of senescent red blood cells by forming prophagocytic platelet-cell complexes
Published in Blood (08-02-2024)“…•Senescent RBCs are bound to platelets, forming P-RBC complexes that are selectively consumed by erythrophagocytes.•A sufficient supply of platelets is…”
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Novel scientific approaches and future research directions in understanding ITP
Published in Platelets (Edinburgh) (02-04-2020)“…Diagnosis of immune thrombocytopenia (ITP) and prediction of response to therapy remain significant and constant challenges in hematology. In patients who…”
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The molecular basis of immune-based platelet disorders
Published in Clinical science (1979) (13-11-2020)“…Platelets have a predominant role in haemostasis, the maintenance of blood volume and emerging roles as innate immune cells, in wound healing and in…”
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A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia
Published in Blood advances (14-06-2022)“…Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe prothrombotic complication of adenoviral vaccines, including the ChAdOx1 nCoV-19…”
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Rilzabrutinib, an Oral BTK Inhibitor, in Immune Thrombocytopenia
Published in The New England journal of medicine (14-04-2022)“…Sixty patients with ITP were enrolled in a phase 1–2 trial of the Bruton’s tyrosine kinase inhibitor rilzabrutinib for increasing platelet count. During 24…”
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SkM‐ing information from traumatized tissue
Published in Journal of thrombosis and haemostasis (01-06-2022)Get full text
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R2 and R2 MRI assessment of liver iron content in an undifferentiated diagnostic population with hyperferritinaemia, and impact on clinical decision making
Published in European journal of radiology (01-02-2021)“…•R2* is accurate in hyperferritinaemia, and highly correlated with R2 (Ferriscan®).•R2 and R2* MRI results altered clinical management in >44 % of patients…”
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The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters
Published in Journal of thrombosis and haemostasis (01-08-2021)Get full text
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Consensus guidelines for the management of adult immune thrombocytopenia in Australia and New Zealand
Published in Medical journal of Australia (17-01-2022)“…Introduction The absence of high quality evidence for basic clinical dilemmas in immune thrombocytopenic purpura (ITP) underlines the need for contemporary…”
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Response to COVID‐19 vaccination in patients on cancer therapy: Analysis in a SARS‐CoV‐2‐naïve population
Published in Asia-Pacific journal of clinical oncology (01-06-2024)“…Background Cancer patients have increased morbidity and mortality from COVID‐19, but may respond poorly to vaccination. The Evaluation of COVID‐19 Vaccination…”
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Long-term treatment with rilzabrutinib in patients with immune thrombocytopenia
Published in Blood advances (09-04-2024)“…•With extended treatment, responses with rilzabrutinib were durable as a monotherapy and with the use of concomitant ITP medication.•Oral rilzabrutinib was…”
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Immune thrombocytopenia: antiplatelet autoantibodies inhibit proplatelet formation by megakaryocytes and impair platelet production in vitro
Published in Haematologica (Roma) (01-05-2015)“…Primary immune thrombocytopenia is an autoimmune disease mediated by antiplatelet autoantibodies that cause platelet destruction and suppression of platelet…”
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15
High‐dose intravenous flucloxacillin may affect warfarin therapy
Published in Medical journal of Australia (01-06-2011)Get full text
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Perinephric haematopoiesis
Published in Medical journal of Australia (18-02-2008)Get full text
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Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
Published in The New England journal of medicine (15-07-2021)Get full text
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Platelets Bind Senescent Red Blood Cells and Mediate Their Clearance from the Circulation
Published in Blood (15-11-2022)Get full text
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Platelets mediate the clearance of senescent red blood cells by forming pro-phagocytic platelet-cell complexes
Published in Blood (22-11-2023)“…In humans approximately 0.1-0.3% of circulating red blood cells (RBC) are present as platelet-RBC (P-RBC) complexes, and 1-2% in mice. Excessive P-RBC…”
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Physicochemical surface interactions of nanoimprint lithography resists and imprinted pore membranes
Published 01-01-2010“…This dissertation begins by presenting the use of inorganic copolymer imprint resists, namely siloxane graft and block copolymers. These new materials are…”
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Dissertation